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Yu Yang
Basic Medical Sciences
Peking Union Medical College
Beijing
Language: English, Chinese
Neural Development
Gene Expression
Transcriptional Regulation
Post-Transcriptional Regulation
Neurogenesis
Rna Processing
Molecular Biology
Biochemistry
Cell Biology
Bioinformatics
Areas of Focus
- Gene expression regulation during neural development
Work Experience
- 2019-present - Chinese Academy of Medical Sciences, Institute of Basic Medical Sciences - Associate Researcher
- 2014-2019 - Sloan Kettering Institute, Eric Lai Lab - Postdoctoral Researcher
Publications
- Unanticipated broad phylogeny of BEN DNA-binding domains revealed by structural homology searches, Pan, A., Zeng, Y., Liu, J., Zhou, M., Lai, E.C., and Yu, Y., 2023
- Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins, Zheng L, Liu J., Niu L, Kamran M, Yang AWH, Jolma A, Dai Q, Hughes TR, Patel DJ, Zhang L, Prasanth SG, Yu, Y., Ren A, Lai EC, 2022
- Regulation of embryonic and adult neurogenesis by Ars2, Yu, Y., Andreu-Agullo, C., Liu, B., Barboza, L., Toth, M., Lai, E., 2020
- Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation, Yu, Y., Chen, Y., Kim, B., Wang H, Zhao C, He X, Liu L, Liu W, Wu LM, Mao M, Chan JR, Wu J, Lu QR., 2013
- XPO5 promotes primary miRNA processing independently of RanGTP, Wang JJ, Lee J., Riemondy K., Yu Y, Marquez S., Lai E., and Yi R, 2020
- TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex, Lv X, Ren SQ, Zhang XJ, Shen Z, Ghosh T, Xianyu A, Gao P, Li Z, Lin S, Yu Y, Zhang Q, Groszer M, Shi SH, 2019
- The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma, He X, Zhang L, Chen Y, Remke M, Shih D, Lu F, Wang H, Deng Y, Yu Y, Xia Y, Wu X, Ramaswamy V, Hu T, Wang F, Zhou W, Burns DK, Kim SH, Kool M, Pfister SM, Weinstein LS, Pomeroy SL, Gilbertson RJ, Rubin JB, Hou Y, Wechsler-Reya R, Taylor MD, Lu QR, 2014
- Unwrapping myelination by microRNAs, He, X., Yu, Y., Awatramani, R., and Lu, Q.R., 2012
- Shaping the oligodendrocyte identity by epigenetic control, Yu, Y., Casaccia, P., and Lu, Q.R., 2010
- MicroRNA-mediated control of oligodendrocyte differentiation, Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QR., 2010
