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Yan Jiang
Brain Science Research Institute
Fudan University
Shanghai
Language: English, Chinese
Epigenetics
Brain Development
Neuroscience
Gene Expression
Chromatin
Dna Methylation
Histone Modification
Genomic Editing
Neurodevelopmental Disorders
Molecular Mechanisms
Areas of Focus
- Epigenetic regulation mechanisms in brain development and diseases
Work Experience
- 2010-2012 - UT Southwestern Medical Center - Postdoctoral Training
- 2012-2018 - Icahn School of Medicine at Mount Sinai - Lecturer, Research Assistant Professor
- 2018-present - Fudan University Brain Science Institute - Researcher
Academic Background & Achievements
- 2009 - PhD: University of Massachusetts Medical School
- 2010 - NARSAD Young Investigator Award
Publications
- Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions, Chandrasekaran S, Espeso-Gil S, Loh YHE, Javidfar B, Kassim B, Zhu YY, Zhang Y, Dong YH, Bicks LK, Li HX, Rajarajan P, Peter CJ, Sun DJ, Agullo-Pascual E, Iskhakova M, Estill M, Lesch BJ, Shen L, Jiang Y*, Akbarian S*, 2021
- 3D genome organization in the central nervous system, implications for neuropsychological disorders, Sun D, Weng J, Dong Y, Jiang Y*, 2021
- A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons, Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, Borrman T, Wiseman J, Bell A, Bannon MJ, Roussos P, Crary JF, Weng Z, Marenco S, Lipska B, Tsankova NM, Huckins L, Jiang Y*, Akbarian S*, 2020
- Epigenetic mechanism of SETDB1 in brain: implications for neuropsychiatric disorders, Zhu Y, Sun D, Jakovcevski M, Jiang Y*, 2020
- The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain, Jiang Y#, Loh YHE#, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, Julia TCW, Safaie BM, Morishita H, Roussos P, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S*, 2017
Awards
- 2010 - NARSAD Young Investigator Award
