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Minjie Shen
Brain Science Research Institute
Fudan University
Shanghai
Language: English, Chinese
Neurodevelopment
Molecular Mechanisms
Genetic Regulation
Protein Dysfunction
Cellular Function
Transgenic Mice
Human Neurons
Molecular Biology
Cell Biology
Pharmacology
Areas of Focus
- Molecular mechanisms of neurodevelopmental disorders
- Molecular targeted therapy and translational research for neurodevelopmental disorders
Work Experience
- 2016-2023 - University of Wisconsin-Madison - Postdoctoral Research
- 2023-Present - Fudan University Brain Science Institute - Group Leader, Independent PI
Academic Background & Achievements
- 2011 - Medical Bachelor's Degree: Fudan University
- 2016 - PhD in Pharmacology: Fudan University
- Achievement: Published in journals like Nature Neuroscience, Neuron, Molecular Psychiatry
Publications
- Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development., Shen M, Sirois CL, Guo Y, Li M, Dong Q, Méndez-Albelo NM, Gao Y, Khullar S, Kissel L, Sandoval SO, Wolkoff NE, Huang SX, Xu Z, Bryan JE, Contractor AM, Korabelnikov T, Glass IA, Doherty D; Birth Defects Research Laboratory; Levine JE, Sousa AMM, Chang Q, Bhattacharyya A, Wang D, Werling DM, Zhao X*, 2023
- FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors., Shen M, Guo Y, Dong Q, Gao Y, Stockton ME, Li M, Kannan S, Korabelnikov T, Schoeller KA, Sirois CL, Zhou C, Le J, Wang D, Chang Q, Sun QQ, Zhao X*, 2021
- Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice., Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya, A, van Praag H, Zhao X*, 2019
- GRK5 Regulates Social Behavior Via Suppression of mTORC1 Signaling in Medial Prefrontal Cortex., Niu B#, Liu P#, Shen M#, Liu C, Wang L, Wang F, Ma L*, 2018
- Mesolimbic leptin signaling negatively regulates cocaine-conditioned reward., Shen M, Jiang C, Liu P, Wang F, Ma L*, 2016
Awards
- FRAXA Research Foundation Grant (2019-2021)
