Upload Avatar (500 x 500)
Zhixiang Xu
Brain Science Research Institute
Fudan University
Shanghai
Language: English, Chinese
Neuroimmune Cells
Microglia
Physiological States
Pathological States
Autism
Neuroimmunology
Transgenic Mice
Drosophila
Molecular Mechanisms
Cellular Mechanisms
Areas of Focus
- Function of neuroimmune cells (microglia) in physiological and pathological states
- Neuroimmunological basis of autism
Work Experience
- 2013-2020 - Postdoctoral Research: Scripps Research Institute, Department of Neurobiology
- 2020-present - Group Leader: Fudan University, Institute of Brain Science
Academic Background & Achievements
- 2008 - Bachelor's Degree: Huazhong University of Science and Technology, Tongji Medical College, School of Pharmacy
- 2013 - Doctorate: University of Chinese Academy of Sciences
- Published research in journals such as Nature Communications and Cell Metabolism
Publications
- HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury., Huang YC, Meng S, Wu BW, Shi H, Wang YN, Xiang JK, Li JY, Shi ZY, Wu G, Lyu YC, Jia X, Hu J, Xu ZX*, Gao YQ*, 2023
- Dissecting the neurovascular unit in physiology and Alzheimer's disease: Functions, imaging tools and genetic mouse models., Li TT, Li DY, Wei QY, Shi MH, Xiang JK, Gao RW*, Chen C*, Xu ZX*, 2023
- Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations., Xu ZX, Kim GH, Tan JW, Riso AE, Sun Y, Xu EY, Liao GY, Xu HF, Lee SH, Do NY, Lee CH, Clipperton-Allen AE, Kwon S, Page DT, Lee KJ, Xu BJ*, 2020
- Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling., Xu ZX, Tan JW, Xu HF, Hill CJ, Ostrovskaya O, Martemyanow KA, Xu BJ*, 2019
- Activation of anxiogenic circuits instigates resistance to diet-induced obesity via increased energy expenditure., Xie XY, Yang HL, An JJ, Houtz J, Tan JW, Xu HF, Liao GY, Xu ZX, Xu BJ*, 2019
