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Bo Zhang
College of Chemical Biology and Biotechnology
Peking University
Guangdong
Language: English, Chinese
Synapse
Formation
Maintenance
Molecular
Basis
Neurological
Psychiatric
Diseases
Structure
Function
Areas of Focus
- Molecular basis of synapse formation and maintenance, and the role of synaptic structure/function disorders in neurological and psychiatric diseases.
Work Experience
- 2020.05 - Present: Distinguished Researcher, Shenzhen Bay Laboratory
- 2019.01 - Present: Distinguished Researcher, Peking University Shenzhen Graduate School
- 2017.09 - 2018.12: Basic Research Scientist, Stanford University
- 2011.09 - 2017.08: Postdoctoral Researcher, Stanford University/Howard Hughes Medical Institute
Academic Background & Achievements
- 2020.05 - Present: Distinguished Researcher, Shenzhen Bay Laboratory
- 2019.01 - Present: Distinguished Researcher, Peking University Shenzhen Graduate School
- 2017.09 - 2018.12: Basic Research Scientist, Stanford University
- 2011.09 - 2017.08: Postdoctoral Researcher, Stanford University/Howard Hughes Medical Institute
- 2005.09 - 2011.07: Ph.D., Peking University
- 2001.09 - 2005.07: Bachelor's, Central University for Nationalities
Publications
- Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number., Qin, L., Liu, Z., Guo, S., Han, Y., Wang, X., Ren, W., Chen, J., Zhen, H., Nie, C., Xing, K., Chen, T., Südhof TC, Sun, Y., Zhang, B., 2024
- Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus., Lloyd, B.A., Han, Y., Roth, R., Zhang, B., Aoto, J., 2023
- Cocaine increases quantal norepinephrine secretion through NET-dependent PKC activation in locus coeruleus neurons., Zhu, F., Liu, L., Li, J., Liu, B., Wang, Q., Jiao R., Xu, Y., Wang, L., Sun, S., Sun, X., Younus, M., Wang, C., Hokfel, T., Zhang, B., Gu, H., Xu, Z., Zhou, Z., 2022
- Neuroligin-3 confines AMPA-receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses., Han, Y., Cao, R., Qin, L., Chen, L., Tang, A., Südhof, TC, Zhang, B., 2022
- Functional mosaic organization of neuroligins in neuronal circuits., Qin, L., Guo, S., Han, Y., Wang, X., Zhang, B., 2020
- Autism-associated Neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses., Zhang, B., Gokce, O., Hale, D., Brose, N., Südhof, TC., 2018
- Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held., Zhang, B., Seigneur, E., Wei, P., Gokce, O., Morgan, J., Südhof, TC., 2017
- Neuroligins are selectively essential for NMDA-receptor signaling in cerebellar stellate interneurons., Zhang, B., Südhof, TC., 2016
- Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses., Zhang, B., Chen, L., Maxeiner, S., Lee, S., Gokce, O., Südhof, TC., 2015
Awards
- 2023: Shenzhen Government Special Allowance Expert
- 2022: Advanced Individual in Reform and Innovation, Guangming District, Shenzhen
- 2020: National Natural Science Foundation of China Excellent Young Scientists Fund
- 2019: Guangdong Pearl River Talent Plan - Introduced Young Top Talent
