Professor | Ruan Ke | Asia Growth Partners

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Name	Ruan Ke
Contact Information	kruan@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Ruan Ke

Contact Information

kruan@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	Bachelor's and Master's Degree: Peking University, College of Chemistry and Molecular Engineering Ph.D.: Johns Hopkins University

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

Bachelor's and Master's Degree: Peking University, College of Chemistry and Molecular Engineering
Ph.D.: Johns Hopkins University

Areas of Focus	Drug discovery and development Protein-ligand interactions NMR spectroscopy applications
Publications	Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the limit of NMR Intermediate Exchange, Gao J, Liang E, Ma R, Li F, Liu Y, Liu J, Jiang L, Li C, Dai H, Wu J, Su X, He W, Ruan K, 2017 Repurposing low–molecular-weight drugs against the main protease of severe acute respiratory syndrome coronavirus 2, Gao J, Zhang L, Liu X, Li F, Ma R, Zhu Z, Zhang J, Wu J, Shi Y, Pan Y, Ge Y, Ruan K, 2020 Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1, Lv M, Gao J, Li M, Ma R, Li F, Liu Y, Liu M, Zhang J, Yao X, Wu J, Shi Y, Tang Y, Pan Y, Zhang Z, Ruan K, 2020 Ligand Proton Pseudocontact Shifts Determined from Paramagnetic Relaxation Dispersion in the Limit of NMR Intermediate Exchange, Xu D, Li B, Gao J, Liu Z, Niu X, Nshogoza G, Zhang J, Wu J, Su XC, He W, Ma R, Yang D, Ruan K, 2018 Dynamic Nature of CTCF Tandem 11 Zinc Fingers in Multivalent Recognition of DNA As Revealed by NMR Spectroscopy, Xu D, Ma R, Zhang J, Liu Z, Wu B, Peng J, Zhai Y, Gong Q, Shi Y, Wu J, Wu Q, Zhang Z, Ruan K, 2018

Areas of Focus

Drug discovery and development
Protein-ligand interactions
NMR spectroscopy applications

Publications

Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the limit of NMR Intermediate Exchange, Gao J, Liang E, Ma R, Li F, Liu Y, Liu J, Jiang L, Li C, Dai H, Wu J, Su X, He W, Ruan K, 2017
Repurposing low–molecular-weight drugs against the main protease of severe acute respiratory syndrome coronavirus 2, Gao J, Zhang L, Liu X, Li F, Ma R, Zhu Z, Zhang J, Wu J, Shi Y, Pan Y, Ge Y, Ruan K, 2020
Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1, Lv M, Gao J, Li M, Ma R, Li F, Liu Y, Liu M, Zhang J, Yao X, Wu J, Shi Y, Tang Y, Pan Y, Zhang Z, Ruan K, 2020
Ligand Proton Pseudocontact Shifts Determined from Paramagnetic Relaxation Dispersion in the Limit of NMR Intermediate Exchange, Xu D, Li B, Gao J, Liu Z, Niu X, Nshogoza G, Zhang J, Wu J, Su XC, He W, Ma R, Yang D, Ruan K, 2018
Dynamic Nature of CTCF Tandem 11 Zinc Fingers in Multivalent Recognition of DNA As Revealed by NMR Spectroscopy, Xu D, Ma R, Zhang J, Liu Z, Wu B, Peng J, Zhai Y, Gong Q, Shi Y, Wu J, Wu Q, Zhang Z, Ruan K, 2018

Drug Discovery Protein Modification Nmr Spectroscopy Ligand Recognition Molecular Mechanism Covid-19 Clinical Research Protein Dynamics Fragment-Based Screening Lead Compound

Meichun Deng - Central South University

Meichun Deng - Central South University

Qiansen Zhang - East China Normal University

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