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Chen Chun Weng
Life Science
University of Science and Technology of China
Anhui
Language: English, Chinese
Big Data
Quantitative Analysis
Biomolecules
Allosteric Regulation
Signal Transduction
Cancer
Protein Interactions
Kras
Computational Biology
Structural Biology
Areas of Focus
- Quantitative biological big data mining, processing, and analysis
- Allosteric regulation mechanisms of biomolecules
- Signal transduction and cancer
Work Experience
- 2014-2019 - University of Science and Technology of China - PhD Student
- 2019-2020 - University of Science and Technology of China - Postdoctoral Researcher
- 2020-2024 - Centre for Genomic Regulation, Spain - Postdoctoral Researcher
Academic Background & Achievements
- 2014-2019 PhD in Genetics: University of Science and Technology of China
- 2019-2020 Postdoctoral Research: University of Science and Technology of China
- 2020-2024 Postdoctoral Research: Centre for Genomic Regulation, Spain
Publications
- The energetic and allosteric landscape for KRAS inhibition, Weng, C., Faure, A.J., Escobedo, A., & Lehner, B., 2023
- The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans, Weng, C.*, Kosalka, J.*, Berkyurek, A.C.*, Stempor, P., Feng, X., Mao, H., Zeng, C., Li, W.J., Yan, Y.H., Dong, M.Q., Morero, N. R., Zuliani, C., Barabas, O., Ahringer, J., Guang, S., Miska, E. A., 2019
- Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation, Zeng, C.*, Weng, C.*, Wang, X.*, Yan, Y.H.*, Li, W.J., Xu, D., Hong, M., Liao, S., Dong, M.Q., Feng, X., et al., 2019
- CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA, Wang, Y.*, Weng, C.*, Chen, X., Zhou, X., Huang, X., Yan, Y., & Zhu, C., 2020
- A chromodomain protein mediates heterochromatin-directed piRNA expression, Huang, X.*, Cheng, P.*, Weng, C., Xu, Z., Zeng, C., Xu, Z., Chen, X., Zhu, C., Guang, S., & Feng, X., 2021
- Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA, Zhu, C.*, Yan, Q.*, Weng, C., Hou, X., Mao, H., Liu, D., Feng, X., and Guang, S., 2018
- A Cytoplasmic Argonaute Protein Promotes the Inheritance of RNAi, Xu, F.*, Feng, X.*, Chen, X., Weng, C., Yan, Q., Xu, T., Hong, M., and Guang, S., 2018
- The Nrde Pathway Mediates Small-RNA-Directed Histone H3 Lysine 27 Trimethylation in Caenorhabditis elegans, Mao, H.*, Zhu, C.*, Zong, D., Weng, C., Yang, X., Huang, H., Liu, D., Feng, X., and Guang, S., 2015
- Association of decreased expression of the macrophage scavenger receptor MARCO with tumor progression and poor prognosis in human hepatocellular carcinoma, Sun, H., Song, J., Weng, C., Xu, J., Huang, M., Huang, Q., Sun, R., Xiao, W., & Sun, C., 2017
- The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore, Sun, C., Xu, J., Song, J., Liu, C., Wang, J., Weng, C., Sun, H., Wei, H., Xiao, W., Sun, R., & Tian, Z., 2015
