Professor | Chen Chun Weng | Asia Growth Partners

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Name	Chen Chun Weng
Contact Information	wcc9294@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Chen Chun Weng

Contact Information

wcc9294@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	2014-2019 PhD in Genetics: University of Science and Technology of China 2019-2020 Postdoctoral Research: University of Science and Technology of China 2020-2024 Postdoctoral Research: Centre for Genomic Regulation, Spain
Work Experience	2014-2019 - University of Science and Technology of China - PhD Student 2019-2020 - University of Science and Technology of China - Postdoctoral Researcher 2020-2024 - Centre for Genomic Regulation, Spain - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

2014-2019 PhD in Genetics: University of Science and Technology of China
2019-2020 Postdoctoral Research: University of Science and Technology of China
2020-2024 Postdoctoral Research: Centre for Genomic Regulation, Spain

Work Experience

2014-2019 - University of Science and Technology of China - PhD Student
2019-2020 - University of Science and Technology of China - Postdoctoral Researcher
2020-2024 - Centre for Genomic Regulation, Spain - Postdoctoral Researcher

Areas of Focus	Quantitative biological big data mining, processing, and analysis Allosteric regulation mechanisms of biomolecules Signal transduction and cancer
Publications	The energetic and allosteric landscape for KRAS inhibition, Weng, C., Faure, A.J., Escobedo, A., & Lehner, B., 2023 The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans, Weng, C., Kosalka, J., Berkyurek, A.C., Stempor, P., Feng, X., Mao, H., Zeng, C., Li, W.J., Yan, Y.H., Dong, M.Q., Morero, N. R., Zuliani, C., Barabas, O., Ahringer, J., Guang, S., Miska, E. A., 2019 Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation, Zeng, C., Weng, C., Wang, X., Yan, Y.H., Li, W.J., Xu, D., Hong, M., Liao, S., Dong, M.Q., Feng, X., et al., 2019 CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA, Wang, Y., Weng, C., Chen, X., Zhou, X., Huang, X., Yan, Y., & Zhu, C., 2020 A chromodomain protein mediates heterochromatin-directed piRNA expression, Huang, X., Cheng, P., Weng, C., Xu, Z., Zeng, C., Xu, Z., Chen, X., Zhu, C., Guang, S., & Feng, X., 2021 Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA, Zhu, C., Yan, Q., Weng, C., Hou, X., Mao, H., Liu, D., Feng, X., and Guang, S., 2018 A Cytoplasmic Argonaute Protein Promotes the Inheritance of RNAi, Xu, F., Feng, X., Chen, X., Weng, C., Yan, Q., Xu, T., Hong, M., and Guang, S., 2018 The Nrde Pathway Mediates Small-RNA-Directed Histone H3 Lysine 27 Trimethylation in Caenorhabditis elegans, Mao, H., Zhu, C.*, Zong, D., Weng, C., Yang, X., Huang, H., Liu, D., Feng, X., and Guang, S., 2015 Association of decreased expression of the macrophage scavenger receptor MARCO with tumor progression and poor prognosis in human hepatocellular carcinoma, Sun, H., Song, J., Weng, C., Xu, J., Huang, M., Huang, Q., Sun, R., Xiao, W., & Sun, C., 2017 The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore, Sun, C., Xu, J., Song, J., Liu, C., Wang, J., Weng, C., Sun, H., Wei, H., Xiao, W., Sun, R., & Tian, Z., 2015

Areas of Focus

Quantitative biological big data mining, processing, and analysis
Allosteric regulation mechanisms of biomolecules
Signal transduction and cancer

Publications

The energetic and allosteric landscape for KRAS inhibition, Weng, C., Faure, A.J., Escobedo, A., & Lehner, B., 2023
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans, Weng, C.*, Kosalka, J.*, Berkyurek, A.C.*, Stempor, P., Feng, X., Mao, H., Zeng, C., Li, W.J., Yan, Y.H., Dong, M.Q., Morero, N. R., Zuliani, C., Barabas, O., Ahringer, J., Guang, S., Miska, E. A., 2019
Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation, Zeng, C.*, Weng, C.*, Wang, X.*, Yan, Y.H.*, Li, W.J., Xu, D., Hong, M., Liao, S., Dong, M.Q., Feng, X., et al., 2019
CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA, Wang, Y.*, Weng, C.*, Chen, X., Zhou, X., Huang, X., Yan, Y., & Zhu, C., 2020
A chromodomain protein mediates heterochromatin-directed piRNA expression, Huang, X.*, Cheng, P.*, Weng, C., Xu, Z., Zeng, C., Xu, Z., Chen, X., Zhu, C., Guang, S., & Feng, X., 2021
Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA, Zhu, C.*, Yan, Q.*, Weng, C., Hou, X., Mao, H., Liu, D., Feng, X., and Guang, S., 2018
A Cytoplasmic Argonaute Protein Promotes the Inheritance of RNAi, Xu, F.*, Feng, X.*, Chen, X., Weng, C., Yan, Q., Xu, T., Hong, M., and Guang, S., 2018
The Nrde Pathway Mediates Small-RNA-Directed Histone H3 Lysine 27 Trimethylation in Caenorhabditis elegans, Mao, H.*, Zhu, C.*, Zong, D., Weng, C., Yang, X., Huang, H., Liu, D., Feng, X., and Guang, S., 2015
Association of decreased expression of the macrophage scavenger receptor MARCO with tumor progression and poor prognosis in human hepatocellular carcinoma, Sun, H., Song, J., Weng, C., Xu, J., Huang, M., Huang, Q., Sun, R., Xiao, W., & Sun, C., 2017
The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore, Sun, C., Xu, J., Song, J., Liu, C., Wang, J., Weng, C., Sun, H., Wei, H., Xiao, W., Sun, R., & Tian, Z., 2015

Big Data Quantitative Analysis Biomolecules Allosteric Regulation Signal Transduction Cancer Protein Interactions Kras Computational Biology Structural Biology

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