Professor | Wei Xiong | Asia Growth Partners

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Name	Wei Xiong
Contact Information	wxiong@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

Upload Avatar (500 x 500)

Name

Wei Xiong

Contact Information

wxiong@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	2001 - Bachelor of Science: Peking University, School of Life Sciences 2006 - Doctor of Science: Peking University, School of Life Sciences Recipient of the National Science Fund for Distinguished Young Scholars Recipient of the National High-Level Talent Special Support Program for Scientific and Technological Innovation Leading Talents
Work Experience	2006-2013 - Postdoctoral Research: National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH, USA 2013-present - Executive Dean: School of Life Sciences, University of Science and Technology of China
Awards	Outstanding Research Principal Award, University of Science and Technology of China Excellent Mentor Award, Chinese Academy of Sciences Tang Lixin Excellent Scholar Award

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

2001 - Bachelor of Science: Peking University, School of Life Sciences
2006 - Doctor of Science: Peking University, School of Life Sciences
Recipient of the National Science Fund for Distinguished Young Scholars
Recipient of the National High-Level Talent Special Support Program for Scientific and Technological Innovation Leading Talents

Work Experience

2006-2013 - Postdoctoral Research: National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH, USA
2013-present - Executive Dean: School of Life Sciences, University of Science and Technology of China

Awards

Outstanding Research Principal Award, University of Science and Technology of China
Excellent Mentor Award, Chinese Academy of Sciences
Tang Lixin Excellent Scholar Award

Areas of Focus	Neural circuit mechanisms of perception and related diseases Development of novel neurochemical technologies Research on neurodegenerative diseases using single-cell mass spectrometry Regulation mechanisms of ligand-gated ion channels
Publications	ACE2-expressing cerebral vascular endothelial cells and post COVID-19 patients, Jieping Lu, Xin Zuo, Aoling Cai, Fang Xiao, Zhenyu Xu, Rui Wang, Chenjian Miao, Chen Yang, Xingxing Zheng, Jie Wang, Xiaoling Ding, Wei Xiong, 2024 LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination, Xiaolin Lian, Meng Gong, Zhikai Wang, Jie Wang, Weiwei Guo, Aoling Cai, Zhenye Yang, Xing Liu, Fuqiang Xu, Wei Xiong, Chuanhai Fu, Xiangting Wang, 2024 From gut microbiota to brain: implications on binge eating disorders, Weiwei Guo, Wei Xiong, 2024 PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury, Qianping Zhang, Tiantian Sun, Fan Yu, Wei Liu, Jin Gao, Jinyu Chen, Hao Zheng, Jinming Liu, Chenjian Miao, Huanyi Guo, Wu Tian, Meihui Su, Yingjie Guo, Xi Liu, Yandong Pei, Zhuofei Wang, Shang Chen, Chenglong Mu, Sin Man Lam, Guanghou Shui, Zongjin Li, Zhongbo Yu, Yan Zhang, Guo Chen, Congcong Lu, Adam C. Midgley, Changhua Li, Xin Bian, Xudong Liao, Yong Wang, Wei Xiong, Hongying Zhu, Yanjun Li, Quan Chen, 2024 Microbiota-Gut-Brain Axis Drives Overeating Disorders, Sijia Fan, Weiwei Guo, Dan Xiao, Mengyuan Guan, Tiepeng Liao, Sufang Peng, Airong Feng, Ziyi Wang, Hao Yin, Min Li, Jue Chen, Wei Xiong, 2023 Advances in mass spectrometry-based multi-scale metabolomic methodologies and their applications in biological and clinical investigations, Ziyi Wang, Hongying Zhu, Wei Xiong, 2023 The cannabinoid dehydroxylcannabidiol suppresses neuropathic pain by upregulating a spinal glycine receptor-mediated compensation mechanism, Jing Xia, Dan Xiao, Heyi Luo, Jin Jin, Siyuan Ge, Xianglian Wang, Guichang Zou, Wei Xiong, 2023 A super-resolution strategy for mass spectrometry imaging via transfer learning, Tiepeng Liao, Zihao Ren, Zhaoliang Chai, Man Yuan, Chenjian Miao, Junjie Li, Qi Chen, Zhilin Li, Ziyi Wang, Lin Yi, Siyuan Ge, Wenwei Qian, Zilei Wang, Wei Xiong, Hongying Zhu, 2023 Coordinated activity of a central pathway drives associative opioid analgesic tolerance, Yiwen Hou, Guichang Zou, Xianglian Wang, Hui Guo, Xiao Ma, Xingyu Cheng, Zhiyong Xie, Xin Zuo, Jing Xia, Huanhuan Mao, Man Yuan, Qi Chen, Peng Cao, Yupeng Yang, Li Zhang, Wei Xiong, 2023 Fat shapes fate: unlock the destiny of a cell with single-cell metabolomics, Ziyi Wang, Fei Sun, Wei Xiong, 2022 A midbrain-reticulotegmental circuit underlies exaggerated startle under fear emotions, Weiwei Guo, Sijia Fan, Dan Xiao, Chen He, Mengyuan Guan, Wei Xiong, 2022 Combined alcohol and cannabinoid exposure leads to synergistic toxicity by affecting cerebellar Purkinje cells, Guichang Zou, Jing Xia, Heyi Luo, Dan Xiao, Jin Jin, Chenjian Miao, Xin Zuo, Qianqian Gao, Zhi Zhang, Tian Xue, Yezi You, Ye Zhang, Li Zhang, Wei Xiong, 2022 A Brainstem reticulotegmental neural ensemble drives acoustic startle reflexes, Weiwei Guo, Sijia Fan, Dan Xiao, Hui Dong, Guangwei Xu, Zhikun Wan, Yuqian Ma, Zhen Wang, Tian Xue, Yifeng Zhou, Yulong Li, Wei Xiong, 2021 Metabolomic profiling of single enlarged lysosomes, Hongying Zhu, Qianqian Li, Tiepeng Liao, Xiang Yin, Qi Chen, Ziyi Wang, Meifang Dai, Lin Yi, Siyuan Ge, Chenjian Miao, Wenping Zeng, Lili Qu, Zhenyu Ju, Guangming Huang, Chunlei Cang, Wei Xiong, 2021 Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice, Yujun Guo, Guichang Zou, Keke Qi, Jin Jin, Lei Yao, Yang Pan, Wei Xiong, 2021 Structural basis of GABARAP-mediated GABAA receptor trafficking and functions on GABAergic synaptic transmission, Jin Ye, Guichang Zou, Ruichi Zhu, Chao Kong, Chenjian Miao, Mingjie Zhang, Jianchao Li, Wei Xiong, Chao Wang, 2021 Cholesterol regulates cannabinoid analgesia through glycine receptors, Lei Yao, Chengyuan Liu, Ning Wang, Feng Du, Sijia Fan, Yujun Guo, Li Zhang, Yang Pan, Wei Xiong, 2020 Membrane cholesterol dependence of cannabinoid modulation of glycine receptor, Lei Yao, Marta Wells, Xiongwu Wu, Yan Xu, Li Zhang, Wei Xiong, 2020 Cannabinoids Rescue Cocaine-Induced Seizures by Restoring Brain Glycine Receptor Dysfunction, Guichang Zou, Xin Zuo, Kai Chen, Yushu Ge, Xiaoqun Wang, Guangwei Xu, Huan Wang, Chenjian Miao, Zhenyu Xu, Shuangshuang Tian, Zhen Wang, Yifeng Zhou, Wei Wei, Guangming Huang, Dan Liu, Wei Xiong, 2020 The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia, Guichang Zou, Jing Xia, Qianqian Han, Dan Liu, Wei Xiong, 2020 Mass Spectrometry Imaging of Brain Cholesterol and Metabolites with Trifluoroacetic Acid-Enhanced Desorption Electrospray Ionization, Xiaoqun Wang, Yiwen Hou, Zhuanghao Hou, Wei Xiong, Guangming Huang, 2019 Imaging of Polar and Nonpolar Species Using Compact Desorption Electrospray Ionization/Postphotoionization Mass Spectrometry, Chengyuan Liu, Keke Qi, Lei Yao, Ying Xiong, Xuan Zhang, Jianye Zang, Changlin Tian, Minggao Xu, Jiuzhong Yang, Zhenkun Lin, Yongmei Lv, Wei Xiong, Yang Pan, 2019 Human Hyperekplexic Mutations in Glycine Receptors Disinhibit the Brainstem by Hijacking GABAA Receptors, Guichang Zou, Qi Chen, Kai Chen, Xin Zuo, Yushu Ge, Yiwen Hou, Tao Pan, Huilin Pan, Dan Liu, Li Zhang, Wei Xiong, 2019 Moderate UV exposure enhances learning and memory by promoting a novel glutamate biosynthetic pathway in the brain, Hongying Zhu, Ning Wang, Lei Yao, Qi Chen, Ran Zhang, Junchao Qian, Yiwen Hou, Weiwei Guo, Sijia Fan, Siling Liu, Qiaoyun Zhao, Feng Du, Xin Zuo, Yujun Guo, Yan Xu, Jiali Li, Tian Xue, Kai Zhong, Xiaoyuan Song, Guangming Huang, Wei Xiong, 2018 Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia, Jieping Lu, Sijia Fan, Guichang Zou, Yiwen Hou, Tao Pan, Weiwei Guo, Lei Yao, Feng Du, GE Homanics, Dan Liu, Li Zhang, Wei Xiong, 2018 Single-neuron identification of chemical constituents, physiological changes, and metabolism using mass spectrometry, Hongying Zhu, Guichang Zou, Ning Wang, Meihui Zhuang, Wei Xiong, Guangming Huang, 2017 Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease, Wei Xiong, Shao-Rui Chen, Liming He, Kejun Cheng, Yi-Lin Zhao, Hong Chen, De-Pei Li, Gregg E. Homanics, John Peever, Kenner C. Rice, Ling-gang Wu, Hui-Lin Pan, Li Zhang, 2014 Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors, Wei Xiong, Tanxing Cui, Kejun Cheng, Fei Yang, Shao-Rui Chen, Dan Willenbring, Yun Guan, Hui-Lin Pan, Ke Ren, Yan Xu, Li Zhang, 2012 A Common Molecular Basis for Exogenous and Endogenous Cannabinoid Potentiation of Glycine Receptors, Wei Xiong, Xiongwu Wu, David M. Lovinger, Li Zhang, 2012 Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia, Wei Xiong, KeJun Chen, Tanxing Cui, Grzegorz Godlewski, Kenner Rice, Yan Xu, Li Zhang, 2011

Areas of Focus

Neural circuit mechanisms of perception and related diseases
Development of novel neurochemical technologies
Research on neurodegenerative diseases using single-cell mass spectrometry
Regulation mechanisms of ligand-gated ion channels

Publications

ACE2-expressing cerebral vascular endothelial cells and post COVID-19 patients, Jieping Lu, Xin Zuo, Aoling Cai, Fang Xiao, Zhenyu Xu, Rui Wang, Chenjian Miao, Chen Yang, Xingxing Zheng, Jie Wang, Xiaoling Ding, Wei Xiong, 2024
LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination, Xiaolin Lian, Meng Gong, Zhikai Wang, Jie Wang, Weiwei Guo, Aoling Cai, Zhenye Yang, Xing Liu, Fuqiang Xu, Wei Xiong, Chuanhai Fu, Xiangting Wang, 2024
From gut microbiota to brain: implications on binge eating disorders, Weiwei Guo, Wei Xiong, 2024
PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury, Qianping Zhang, Tiantian Sun, Fan Yu, Wei Liu, Jin Gao, Jinyu Chen, Hao Zheng, Jinming Liu, Chenjian Miao, Huanyi Guo, Wu Tian, Meihui Su, Yingjie Guo, Xi Liu, Yandong Pei, Zhuofei Wang, Shang Chen, Chenglong Mu, Sin Man Lam, Guanghou Shui, Zongjin Li, Zhongbo Yu, Yan Zhang, Guo Chen, Congcong Lu, Adam C. Midgley, Changhua Li, Xin Bian, Xudong Liao, Yong Wang, Wei Xiong, Hongying Zhu, Yanjun Li, Quan Chen, 2024
Microbiota-Gut-Brain Axis Drives Overeating Disorders, Sijia Fan, Weiwei Guo, Dan Xiao, Mengyuan Guan, Tiepeng Liao, Sufang Peng, Airong Feng, Ziyi Wang, Hao Yin, Min Li, Jue Chen, Wei Xiong, 2023
Advances in mass spectrometry-based multi-scale metabolomic methodologies and their applications in biological and clinical investigations, Ziyi Wang, Hongying Zhu, Wei Xiong, 2023
The cannabinoid dehydroxylcannabidiol suppresses neuropathic pain by upregulating a spinal glycine receptor-mediated compensation mechanism, Jing Xia, Dan Xiao, Heyi Luo, Jin Jin, Siyuan Ge, Xianglian Wang, Guichang Zou, Wei Xiong, 2023
A super-resolution strategy for mass spectrometry imaging via transfer learning, Tiepeng Liao, Zihao Ren, Zhaoliang Chai, Man Yuan, Chenjian Miao, Junjie Li, Qi Chen, Zhilin Li, Ziyi Wang, Lin Yi, Siyuan Ge, Wenwei Qian, Zilei Wang, Wei Xiong, Hongying Zhu, 2023
Coordinated activity of a central pathway drives associative opioid analgesic tolerance, Yiwen Hou, Guichang Zou, Xianglian Wang, Hui Guo, Xiao Ma, Xingyu Cheng, Zhiyong Xie, Xin Zuo, Jing Xia, Huanhuan Mao, Man Yuan, Qi Chen, Peng Cao, Yupeng Yang, Li Zhang, Wei Xiong, 2023
Fat shapes fate: unlock the destiny of a cell with single-cell metabolomics, Ziyi Wang, Fei Sun, Wei Xiong, 2022
A midbrain-reticulotegmental circuit underlies exaggerated startle under fear emotions, Weiwei Guo, Sijia Fan, Dan Xiao, Chen He, Mengyuan Guan, Wei Xiong, 2022
Combined alcohol and cannabinoid exposure leads to synergistic toxicity by affecting cerebellar Purkinje cells, Guichang Zou, Jing Xia, Heyi Luo, Dan Xiao, Jin Jin, Chenjian Miao, Xin Zuo, Qianqian Gao, Zhi Zhang, Tian Xue, Yezi You, Ye Zhang, Li Zhang, Wei Xiong, 2022
A Brainstem reticulotegmental neural ensemble drives acoustic startle reflexes, Weiwei Guo, Sijia Fan, Dan Xiao, Hui Dong, Guangwei Xu, Zhikun Wan, Yuqian Ma, Zhen Wang, Tian Xue, Yifeng Zhou, Yulong Li, Wei Xiong, 2021
Metabolomic profiling of single enlarged lysosomes, Hongying Zhu, Qianqian Li, Tiepeng Liao, Xiang Yin, Qi Chen, Ziyi Wang, Meifang Dai, Lin Yi, Siyuan Ge, Chenjian Miao, Wenping Zeng, Lili Qu, Zhenyu Ju, Guangming Huang, Chunlei Cang, Wei Xiong, 2021
Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice, Yujun Guo, Guichang Zou, Keke Qi, Jin Jin, Lei Yao, Yang Pan, Wei Xiong, 2021
Structural basis of GABARAP-mediated GABAA receptor trafficking and functions on GABAergic synaptic transmission, Jin Ye, Guichang Zou, Ruichi Zhu, Chao Kong, Chenjian Miao, Mingjie Zhang, Jianchao Li, Wei Xiong, Chao Wang, 2021
Cholesterol regulates cannabinoid analgesia through glycine receptors, Lei Yao, Chengyuan Liu, Ning Wang, Feng Du, Sijia Fan, Yujun Guo, Li Zhang, Yang Pan, Wei Xiong, 2020
Membrane cholesterol dependence of cannabinoid modulation of glycine receptor, Lei Yao, Marta Wells, Xiongwu Wu, Yan Xu, Li Zhang, Wei Xiong, 2020
Cannabinoids Rescue Cocaine-Induced Seizures by Restoring Brain Glycine Receptor Dysfunction, Guichang Zou, Xin Zuo, Kai Chen, Yushu Ge, Xiaoqun Wang, Guangwei Xu, Huan Wang, Chenjian Miao, Zhenyu Xu, Shuangshuang Tian, Zhen Wang, Yifeng Zhou, Wei Wei, Guangming Huang, Dan Liu, Wei Xiong, 2020
The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia, Guichang Zou, Jing Xia, Qianqian Han, Dan Liu, Wei Xiong, 2020
Mass Spectrometry Imaging of Brain Cholesterol and Metabolites with Trifluoroacetic Acid-Enhanced Desorption Electrospray Ionization, Xiaoqun Wang, Yiwen Hou, Zhuanghao Hou, Wei Xiong, Guangming Huang, 2019
Imaging of Polar and Nonpolar Species Using Compact Desorption Electrospray Ionization/Postphotoionization Mass Spectrometry, Chengyuan Liu, Keke Qi, Lei Yao, Ying Xiong, Xuan Zhang, Jianye Zang, Changlin Tian, Minggao Xu, Jiuzhong Yang, Zhenkun Lin, Yongmei Lv, Wei Xiong, Yang Pan, 2019
Human Hyperekplexic Mutations in Glycine Receptors Disinhibit the Brainstem by Hijacking GABAA Receptors, Guichang Zou, Qi Chen, Kai Chen, Xin Zuo, Yushu Ge, Yiwen Hou, Tao Pan, Huilin Pan, Dan Liu, Li Zhang, Wei Xiong, 2019
Moderate UV exposure enhances learning and memory by promoting a novel glutamate biosynthetic pathway in the brain, Hongying Zhu, Ning Wang, Lei Yao, Qi Chen, Ran Zhang, Junchao Qian, Yiwen Hou, Weiwei Guo, Sijia Fan, Siling Liu, Qiaoyun Zhao, Feng Du, Xin Zuo, Yujun Guo, Yan Xu, Jiali Li, Tian Xue, Kai Zhong, Xiaoyuan Song, Guangming Huang, Wei Xiong, 2018
Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia, Jieping Lu, Sijia Fan, Guichang Zou, Yiwen Hou, Tao Pan, Weiwei Guo, Lei Yao, Feng Du, GE Homanics, Dan Liu, Li Zhang, Wei Xiong, 2018
Single-neuron identification of chemical constituents, physiological changes, and metabolism using mass spectrometry, Hongying Zhu, Guichang Zou, Ning Wang, Meihui Zhuang, Wei Xiong, Guangming Huang, 2017
Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease, Wei Xiong, Shao-Rui Chen, Liming He, Kejun Cheng, Yi-Lin Zhao, Hong Chen, De-Pei Li, Gregg E. Homanics, John Peever, Kenner C. Rice, Ling-gang Wu, Hui-Lin Pan, Li Zhang, 2014
Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors, Wei Xiong, Tanxing Cui, Kejun Cheng, Fei Yang, Shao-Rui Chen, Dan Willenbring, Yun Guan, Hui-Lin Pan, Ke Ren, Yan Xu, Li Zhang, 2012
A Common Molecular Basis for Exogenous and Endogenous Cannabinoid Potentiation of Glycine Receptors, Wei Xiong, Xiongwu Wu, David M. Lovinger, Li Zhang, 2012
Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia, Wei Xiong, KeJun Chen, Tanxing Cui, Grzegorz Godlewski, Kenner Rice, Yan Xu, Li Zhang, 2011

Neural Circuits Perception Cognitive Disorders Epilepsy Chronic Pain Depression Addiction Neurochemical Technology Single-Cell Mass Spectrometry Ion Channels

Bo Chen - University of Chinese Academy of Sciences

Xiaochu Zhang - University of Science and Technology of China

Qian Song - Xi'an Jiaotong University

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