Professor | Zang Jianye | Asia Growth Partners

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Name	Zang Jianye
Contact Information	zangjy@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Zang Jianye

Contact Information

zangjy@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	1998 - Bachelor of Science in Materials Science and Engineering: University of Science and Technology of China 2003 - Doctor of Science in Structural Biology: University of Science and Technology of China
Work Experience	2003-2007 - Postdoctoral Research: National Jewish Health Center, University of Colorado Health Sciences Center Current - Professor: School of Life Sciences, University of Science and Technology of China

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

1998 - Bachelor of Science in Materials Science and Engineering: University of Science and Technology of China
2003 - Doctor of Science in Structural Biology: University of Science and Technology of China

Work Experience

2003-2007 - Postdoctoral Research: National Jewish Health Center, University of Colorado Health Sciences Center
Current - Professor: School of Life Sciences, University of Science and Technology of China

Areas of Focus	Regulation and function of chromatin modification Molecular mechanisms of pathogenic microorganism infection
Publications	Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides, Hang, T., Chen, W., Wu, M., Zhan, L., Wang, C., Jia, N., Zhang, X* and Zang, J., 2019 Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein, Fang, T., Chen, W., Sheng, Y., Yuan, S., Tang, Q., Li, G., Huang, G., Su, J., Zhang, X., Zang, J.* and Liu, Y., 2019 Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail, Wang, C., Zhan, L., Wu, M., Ma, R., Yao, J., Xiong, Y., Pan, Y., Guan, S., Zhang, X. and Zang, J., 2018 Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion, Tian, T., Wang, C., Wu, M., Zhang, X. and Zang, J., 2018 Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore, Tian, T., Li, X., Liu, Y., Wang, C., Liu, X., Bi, G., Zhang, X., Yao, X., Zhou, Z. H., and Zang, J., 2018 Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis, Zhou, X., Zheng, F., Wang, C., Wu, M., Zhang, X., Wang, Q., Yao, X., Fu, C., Zhang, X. and Zang, J., 2017 Structure of the JmjC-domain-containing protein JMJD5, Wang, H., Zhou, X., Wu, M., Wang, C., Zhang, X., Tao, Y., Chen, N., and Zang, J., 2013 Structural Insights into Histone Demethylase NO66 in Interaction with Osteoblast-specific Transcription Factor Osterix and Gene Repression, Tao, Y., Wu, M., Zhou, X., Yin, W., Hu, B., de Crombrugghe, B., Sinha, K.M.* and Zang, J., 2013 Structural Basis for Phosphorylated Autoinducer-2 Modulation of the Oligomerization State of the Global Transcription Regulator LsrR from Escherichia coli, Wu, M., Tao, Y., Liu, X. and Zang, J., 2013 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation, Bian, C., Xu, C., Ruan, J., Lee, K. K., Burke, T. L., Tempel, W., Barsyte, D., Li, J., Wu, M., Zhou, B. O., Fleharty, B. E., Paulson, A., Allali-Hassani, A., Zhou, J. Q., Mer, G., Grant, P. A., Workman, J. L., Zang, J. & Min, J.*, 2011

Areas of Focus

Regulation and function of chromatin modification
Molecular mechanisms of pathogenic microorganism infection

Publications

Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides, Hang, T., Chen, W., Wu, M., Zhan, L., Wang, C., Jia, N., Zhang, X* and Zang, J.*, 2019
Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein, Fang, T., Chen, W., Sheng, Y., Yuan, S., Tang, Q., Li, G., Huang, G., Su, J., Zhang, X.*, Zang, J.* and Liu, Y.*, 2019
Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail, Wang, C., Zhan, L., Wu, M., Ma, R., Yao, J., Xiong, Y., Pan, Y., Guan, S., Zhang, X.* and Zang, J.*, 2018
Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion, Tian, T., Wang, C., Wu, M., Zhang, X.* and Zang, J.*, 2018
Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore, Tian, T., Li, X., Liu, Y., Wang, C., Liu, X., Bi, G., Zhang, X.*, Yao, X.*, Zhou, Z. H.*, and Zang, J.*, 2018
Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis, Zhou, X., Zheng, F., Wang, C., Wu, M., Zhang, X., Wang, Q., Yao, X., Fu, C., Zhang, X.* and Zang, J.*, 2017
Structure of the JmjC-domain-containing protein JMJD5, Wang, H., Zhou, X., Wu, M., Wang, C., Zhang, X., Tao, Y., Chen, N., and Zang, J.*, 2013
Structural Insights into Histone Demethylase NO66 in Interaction with Osteoblast-specific Transcription Factor Osterix and Gene Repression, Tao, Y., Wu, M., Zhou, X., Yin, W., Hu, B., de Crombrugghe, B., Sinha, K.M.* and Zang, J.*, 2013
Structural Basis for Phosphorylated Autoinducer-2 Modulation of the Oligomerization State of the Global Transcription Regulator LsrR from Escherichia coli, Wu, M., Tao, Y., Liu, X. and Zang, J.*, 2013
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation, Bian, C., Xu, C., Ruan, J., Lee, K. K., Burke, T. L., Tempel, W., Barsyte, D., Li, J., Wu, M., Zhou, B. O., Fleharty, B. E., Paulson, A., Allali-Hassani, A., Zhou, J. Q., Mer, G., Grant, P. A., Workman, J. L.*, Zang, J.* & Min, J.*, 2011

Chromatin Modification Regulation Function Molecular Mechanism Pathogen Microorganism Infection Biology

Yue Lou - Shanghai Normal University

Quanhua Wang - Shanghai Normal University

Weihua Huang - Shanghai Normal University

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