Areas of Focus
- Regulation and function of chromatin modification
- Molecular mechanisms of pathogenic microorganism infection
Work Experience
- 2003-2007 - Postdoctoral Research: National Jewish Health Center, University of Colorado Health Sciences Center
- Current - Professor: School of Life Sciences, University of Science and Technology of China
Academic Background & Achievements
- 1998 - Bachelor of Science in Materials Science and Engineering: University of Science and Technology of China
- 2003 - Doctor of Science in Structural Biology: University of Science and Technology of China
Publications
- Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides, Hang, T., Chen, W., Wu, M., Zhan, L., Wang, C., Jia, N., Zhang, X* and Zang, J.*, 2019
- Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein, Fang, T., Chen, W., Sheng, Y., Yuan, S., Tang, Q., Li, G., Huang, G., Su, J., Zhang, X.*, Zang, J.* and Liu, Y.*, 2019
- Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail, Wang, C., Zhan, L., Wu, M., Ma, R., Yao, J., Xiong, Y., Pan, Y., Guan, S., Zhang, X.* and Zang, J.*, 2018
- Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion, Tian, T., Wang, C., Wu, M., Zhang, X.* and Zang, J.*, 2018
- Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore, Tian, T., Li, X., Liu, Y., Wang, C., Liu, X., Bi, G., Zhang, X.*, Yao, X.*, Zhou, Z. H.*, and Zang, J.*, 2018
- Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis, Zhou, X., Zheng, F., Wang, C., Wu, M., Zhang, X., Wang, Q., Yao, X., Fu, C., Zhang, X.* and Zang, J.*, 2017
- Structure of the JmjC-domain-containing protein JMJD5, Wang, H., Zhou, X., Wu, M., Wang, C., Zhang, X., Tao, Y., Chen, N., and Zang, J.*, 2013
- Structural Insights into Histone Demethylase NO66 in Interaction with Osteoblast-specific Transcription Factor Osterix and Gene Repression, Tao, Y., Wu, M., Zhou, X., Yin, W., Hu, B., de Crombrugghe, B., Sinha, K.M.* and Zang, J.*, 2013
- Structural Basis for Phosphorylated Autoinducer-2 Modulation of the Oligomerization State of the Global Transcription Regulator LsrR from Escherichia coli, Wu, M., Tao, Y., Liu, X. and Zang, J.*, 2013
- Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation, Bian, C., Xu, C., Ruan, J., Lee, K. K., Burke, T. L., Tempel, W., Barsyte, D., Li, J., Wu, M., Zhou, B. O., Fleharty, B. E., Paulson, A., Allali-Hassani, A., Zhou, J. Q., Mer, G., Grant, P. A., Workman, J. L.*, Zang, J.* & Min, J.*, 2011