Professor | Xuebiao Yao | Asia Growth Partners

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Name	Xuebiao Yao
Contact Information	yaoxb@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

Upload Avatar (500 x 500)

Name

Xuebiao Yao

Contact Information

yaoxb@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	1995 - Ph.D. in Cell and Molecular Biology: University of California, Berkeley Recipient of the National Science Fund for Distinguished Young Scholars Head of the Innovation Group on Centromere Dynamic Assembly and Regulation
Work Experience	1997 - Assistant Professor, Department of Physiology, Medical College of Wisconsin Director of the Key Laboratory of Cell Dynamics, Ministry of Education Director of the Key Laboratory of Chemical Biology, Anhui Province
Awards	Giannini Scholar Award GCC Distinguished Scientist Award ACS Research Scholar Award

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

1995 - Ph.D. in Cell and Molecular Biology: University of California, Berkeley
Recipient of the National Science Fund for Distinguished Young Scholars
Head of the Innovation Group on Centromere Dynamic Assembly and Regulation

Work Experience

1997 - Assistant Professor, Department of Physiology, Medical College of Wisconsin
Director of the Key Laboratory of Cell Dynamics, Ministry of Education
Director of the Key Laboratory of Chemical Biology, Anhui Province

Awards

Giannini Scholar Award
GCC Distinguished Scientist Award
ACS Research Scholar Award

Areas of Focus	Mechanisms of cell renewal quality control Mechanisms of inflammation and cell plasticity regulation
Publications	Phase separation of EB1 guides microtubule plus-end dynamics., Song X, Yang F, Yang T, Wang Y, Ding M, Li L, Xu P, Liu S, Dai M, Chi C, Xiang S, Xu C, Li D, Wang Z, Li L, Hill DL, Fu C, Yuan K, Li P, Zang J, Hou Z, Jiang K, Shi Y, Liu X, Yao X., 2023 Structural insights into human CCAN complex assembled onto DNA., Tian T, Chen L, Dou Z, Yang Z, Gao X, Yuan X, Wang C, Liu R, Shen Z, Gui P, Teng M, Meng X, Hill DL, Li L, Zhang X, Liu X, Sun L, Zang J, Yao X., 2022 Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis., Song X, Yang F, Liu X, Xia P, Yin W, Wang Z, Wang Y, Yuan X, Dou Z, Jiang K, Ma M, Hu B, Zhang R, Xu C, Zhang Z, Ruan K, Tian R, Li L, Liu T, Hill DL, Zang J, Liu X, Li J, Cheng J, Yao X., 2021 Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation., Xu L, Ali M, Duan W, Yuan X, Garba F, Mullen M, Sun B, Poser I, Duan H, Lu J, Tian R, Ge Y, Chu L, Pan W, Wang D, Hyman A, Green H, Li L, Dou Z, Liu D, Liu X, Yao X., 2021 Phase separation drives decision making in cell division., Liu X, Liu X, Wang H, Dou Z, Ruan K, Hill DL, Li L, Shi Y, Yao X., 2020 BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules., Huang Y, Lin L, Liu X, Ye S, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y, Zhang J, Yang Z, Liu X, Yang Z, Zang J, Teng M, Wang Z, Ruan K, Ding X, Li L, Cleveland DW, Zhang R, Yao X., 2019 NDP52 tunes cortical actin interaction with astral microtubules for accurate spindle orientation., Yu H, Yang F, Dong P, Liao S, Liu WR, Zhao G, Qin B, Dou Z, Liu Z, Liu W, Zang J, Lippincott-Schwartz J, Liu X, Yao X., 2019 Gastric parietal cell physiology and Helicobacter pylori-induced disease., Yao X, Smolka AJ., 2019 Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation., Mo F, Zhuang X, Liu X, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, Yao X., 2016 Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment., Dou Z, Liu X, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL, Yao X., 2015 Phosphorylation of the Bin, Amphiphysin, and RSV161/167 (BAR) domain of ACAP4 regulates membrane tubulation., Zhao X, Wang D, Liu X, Liu L, Song Z, Zhu T, Adams G, Gao X, Tian R, Huang Y, Chen R, Wang F, Liu D, Yu X, Chen Y, Chen Z, Teng M, Ding X, Yao X., 2013 In focus: molecular and cell biology research in China., Yao X, Li D, Pei G., 2013 EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis., Xia P, Wang Z, Liu X, Wu B, Wang J, Ward T, Zhang L, Ding X, Gibbons G, Shi Y, Yao X., 2012 The structure of the FANCM-MHF complex reveals physical features for functional assembly., Tao Y, Jin C, Li X, Qi S, Chu L, Niu L, Yao X, Teng M., 2012 CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3., Chen J, Yao Y, Gong C, Yu F, Su S, Chen J, Liu B, Deng H, Wang F, Lin L, Yao H, Su F, Anderson KS, Liu Q, Ewen ME, Yao X, Song E., 2011 Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin., Ding X, Yan F, Yao P, Yang Z, Wan W, Wang X, Liu J, Gao X, Abrieu A, Zhu T, Zhang J, Dou Z, Yao X., 2010 TIP150 interacts with and targets MCAK at the microtubule plus ends., Jiang K, Wang J, Liu J, Ward T, Wordeman L, Davidson A, Wang F, Yao X., 2009 Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4., Fang Z, Miao Y, Ding X, Deng H, Liu S, Wang F, Zhou R, Watson C, Fu C, Hu Q, Lillard JW Jr, Powell M, Chen Y, Forte JG, Yao X., 2006

Areas of Focus

Mechanisms of cell renewal quality control
Mechanisms of inflammation and cell plasticity regulation

Publications

Phase separation of EB1 guides microtubule plus-end dynamics., Song X, Yang F, Yang T, Wang Y, Ding M, Li L, Xu P, Liu S, Dai M, Chi C, Xiang S, Xu C, Li D, Wang Z, Li L, Hill DL, Fu C, Yuan K, Li P, Zang J, Hou Z, Jiang K, Shi Y, Liu X, Yao X., 2023
Structural insights into human CCAN complex assembled onto DNA., Tian T, Chen L, Dou Z, Yang Z, Gao X, Yuan X, Wang C, Liu R, Shen Z, Gui P, Teng M, Meng X, Hill DL, Li L, Zhang X, Liu X, Sun L, Zang J, Yao X., 2022
Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis., Song X, Yang F, Liu X, Xia P, Yin W, Wang Z, Wang Y, Yuan X, Dou Z, Jiang K, Ma M, Hu B, Zhang R, Xu C, Zhang Z, Ruan K, Tian R, Li L, Liu T, Hill DL, Zang J, Liu X, Li J, Cheng J, Yao X., 2021
Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation., Xu L, Ali M, Duan W, Yuan X, Garba F, Mullen M, Sun B, Poser I, Duan H, Lu J, Tian R, Ge Y, Chu L, Pan W, Wang D, Hyman A, Green H, Li L, Dou Z, Liu D, Liu X, Yao X., 2021
Phase separation drives decision making in cell division., Liu X, Liu X, Wang H, Dou Z, Ruan K, Hill DL, Li L, Shi Y, Yao X., 2020
BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules., Huang Y, Lin L, Liu X, Ye S, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y, Zhang J, Yang Z, Liu X, Yang Z, Zang J, Teng M, Wang Z, Ruan K, Ding X, Li L, Cleveland DW, Zhang R, Yao X., 2019
NDP52 tunes cortical actin interaction with astral microtubules for accurate spindle orientation., Yu H, Yang F, Dong P, Liao S, Liu WR, Zhao G, Qin B, Dou Z, Liu Z, Liu W, Zang J, Lippincott-Schwartz J, Liu X, Yao X., 2019
Gastric parietal cell physiology and Helicobacter pylori-induced disease., Yao X, Smolka AJ., 2019
Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation., Mo F, Zhuang X, Liu X, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, Yao X., 2016
Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment., Dou Z, Liu X, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL, Yao X., 2015
Phosphorylation of the Bin, Amphiphysin, and RSV161/167 (BAR) domain of ACAP4 regulates membrane tubulation., Zhao X, Wang D, Liu X, Liu L, Song Z, Zhu T, Adams G, Gao X, Tian R, Huang Y, Chen R, Wang F, Liu D, Yu X, Chen Y, Chen Z, Teng M, Ding X, Yao X., 2013
In focus: molecular and cell biology research in China., Yao X, Li D, Pei G., 2013
EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis., Xia P, Wang Z, Liu X, Wu B, Wang J, Ward T, Zhang L, Ding X, Gibbons G, Shi Y, Yao X., 2012
The structure of the FANCM-MHF complex reveals physical features for functional assembly., Tao Y, Jin C, Li X, Qi S, Chu L, Niu L, Yao X, Teng M., 2012
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3., Chen J, Yao Y, Gong C, Yu F, Su S, Chen J, Liu B, Deng H, Wang F, Lin L, Yao H, Su F, Anderson KS, Liu Q, Ewen ME, Yao X, Song E., 2011
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin., Ding X, Yan F, Yao P, Yang Z, Wan W, Wang X, Liu J, Gao X, Abrieu A, Zhu T, Zhang J, Dou Z, Yao X., 2010
TIP150 interacts with and targets MCAK at the microtubule plus ends., Jiang K, Wang J, Liu J, Ward T, Wordeman L, Davidson A, Wang F, Yao X., 2009
Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4., Fang Z, Miao Y, Ding X, Deng H, Liu S, Wang F, Zhou R, Watson C, Fu C, Hu Q, Lillard JW Jr, Powell M, Chen Y, Forte JG, Yao X., 2006

Cell Renewal Quality Control Mechanisms Inflammation Cell Plasticity Regulation Dynamics Protein Chromosome Molecular

Jun Qin - University of Chinese Academy of Sciences

Yuangao Wang - University of Chinese Academy of Sciences

Chuanhai Fu - University of Science and Technology of China

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