Upload Avatar (500 x 500)
Li Xu
Life Science
University of Science and Technology of China
Anhui
Language: Chinese, English
Protein
Nucleic Acid
Interaction
Structure
Biofilm
Regulation
Staphylococcus Aureus
Cyanobacteria
Metabolic Pathway
Enzyme
Areas of Focus
- Structural basis of protein-nucleic acid interactions
- Regulatory mechanisms of Staphylococcus aureus biofilm formation
- Cyanobacterial metabolic pathway modification and industrial application
- Enzyme discovery, modification, and industrial application
Work Experience
- 2003 - Present: Teaching at the School of Life Sciences, University of Science and Technology of China
- 2010 - Received Anhui Provincial Outstanding Youth Science Fund
- 2014 - Present: Associate Professor at the School of Life Sciences, University of Science and Technology of China
- 2017 - Present: Deputy Director of the National Life Science Experimental Teaching Demonstration Center, University of Science and Technology of China
- 2018 - Supervisor at Anhui Biochemistry and Molecular Biology Society
- 2019 - Youth Committee Member of the Teaching Professional Committee of the Chinese Society of Biochemistry and Molecular Biology
- 2020 - Youth Committee Member of the Chinese Crystallographic Society
- 2020 - Deputy Secretary of the Party Branch of the School of Life Sciences, University of Science and Technology of China
- 2021 - Member of the Party Committee of the School of Life Sciences and Medicine, University of Science and Technology of China
Academic Background & Achievements
- 2001 - Bachelor of Science: University of Science and Technology of China
- 2007 - Doctor of Science in Structural Biology: University of Science and Technology of China
Publications
- Interface switch mediates signal transmission in a two-component system, Wang M, Guo Q, Zhu K, Fang B, Yang Y, Teng M, Li X*, Tao Y*, 2020
- Structural and Functional Basis of Difructose Anhydride III Hydrolase, Which Sequentially Converts Inulin Using the Same Catalytic Residue, Yu S, Shen H, Cheng Y, Zhu Y, Li X*, Mu W*, 2018
- Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode, Liu Z, Chen P, Wang X, Cai G, Niu L, Teng M*, Li X*, 2014
- Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate, Shao Z, Yan W, Peng J, Zuo X, Zou Y, Li F, Gong D, Ma R, Wu J, Shi Y, Zhang Z, Teng M, Li X*, Gong Q*, 2014
- The structural mechanism for the nucleoside tri- and di-phosphate hydrolysis activity of Ntdp from Staphylococcus aureus, Wang Z, Shen H, He B, Teng M*, Guo Q*, Li X*, 2021
- Caulobacter crescentus β sliding clamp employs a noncanonical regulatory model of DNA replication, Jiang X, Zhang L, An J, Wang M, Teng M*, Guo Q*, Li X*, 2020
- Antibiotic binding releases autoinhibition of the TipA multidrug-resistance transcriptional regulator, Jiang X*, Zhang L, Teng M, Li X*, 2020
- Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation, Zhang W, Zeng F, Liu Y, Zhao Y, Lv H, Niu L, Teng M*, Li X*, 2013
- A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions, Wang Q, Bian X, Zeng L, Pan F, Liu L, Liang J, Wang L, Zhou K, Lee W, Xiang Y, Li S, Teng M, Li X*, Guo X*, Zhang Y*, 2020
- Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins, Zhu Y, Wu B, Zhang X, Fan X, Niu L, Li X*, Wang J*, Teng M*, 2015
Awards
- 2010: Anhui Provincial Outstanding Youth Science Fund
