Professor | Li Xu | Asia Growth Partners

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Name	Li Xu
Contact Information	sachem@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Li Xu

Contact Information

sachem@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	2001 - Bachelor of Science: University of Science and Technology of China 2007 - Doctor of Science in Structural Biology: University of Science and Technology of China
Work Experience	2003 - Present: Teaching at the School of Life Sciences, University of Science and Technology of China 2010 - Received Anhui Provincial Outstanding Youth Science Fund 2014 - Present: Associate Professor at the School of Life Sciences, University of Science and Technology of China 2017 - Present: Deputy Director of the National Life Science Experimental Teaching Demonstration Center, University of Science and Technology of China 2018 - Supervisor at Anhui Biochemistry and Molecular Biology Society 2019 - Youth Committee Member of the Teaching Professional Committee of the Chinese Society of Biochemistry and Molecular Biology 2020 - Youth Committee Member of the Chinese Crystallographic Society 2020 - Deputy Secretary of the Party Branch of the School of Life Sciences, University of Science and Technology of China 2021 - Member of the Party Committee of the School of Life Sciences and Medicine, University of Science and Technology of China
Awards	2010: Anhui Provincial Outstanding Youth Science Fund

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

2001 - Bachelor of Science: University of Science and Technology of China
2007 - Doctor of Science in Structural Biology: University of Science and Technology of China

Work Experience

2003 - Present: Teaching at the School of Life Sciences, University of Science and Technology of China
2010 - Received Anhui Provincial Outstanding Youth Science Fund
2014 - Present: Associate Professor at the School of Life Sciences, University of Science and Technology of China
2017 - Present: Deputy Director of the National Life Science Experimental Teaching Demonstration Center, University of Science and Technology of China
2018 - Supervisor at Anhui Biochemistry and Molecular Biology Society
2019 - Youth Committee Member of the Teaching Professional Committee of the Chinese Society of Biochemistry and Molecular Biology
2020 - Youth Committee Member of the Chinese Crystallographic Society
2020 - Deputy Secretary of the Party Branch of the School of Life Sciences, University of Science and Technology of China
2021 - Member of the Party Committee of the School of Life Sciences and Medicine, University of Science and Technology of China

Awards

2010: Anhui Provincial Outstanding Youth Science Fund

Areas of Focus	Structural basis of protein-nucleic acid interactions Regulatory mechanisms of Staphylococcus aureus biofilm formation Cyanobacterial metabolic pathway modification and industrial application Enzyme discovery, modification, and industrial application
Publications	Interface switch mediates signal transmission in a two-component system, Wang M, Guo Q, Zhu K, Fang B, Yang Y, Teng M, Li X, Tao Y, 2020 Structural and Functional Basis of Difructose Anhydride III Hydrolase, Which Sequentially Converts Inulin Using the Same Catalytic Residue, Yu S, Shen H, Cheng Y, Zhu Y, Li X, Mu W, 2018 Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode, Liu Z, Chen P, Wang X, Cai G, Niu L, Teng M, Li X, 2014 Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate, Shao Z, Yan W, Peng J, Zuo X, Zou Y, Li F, Gong D, Ma R, Wu J, Shi Y, Zhang Z, Teng M, Li X, Gong Q, 2014 The structural mechanism for the nucleoside tri- and di-phosphate hydrolysis activity of Ntdp from Staphylococcus aureus, Wang Z, Shen H, He B, Teng M, Guo Q, Li X, 2021 Caulobacter crescentus β sliding clamp employs a noncanonical regulatory model of DNA replication, Jiang X, Zhang L, An J, Wang M, Teng M, Guo Q, Li X, 2020 Antibiotic binding releases autoinhibition of the TipA multidrug-resistance transcriptional regulator, Jiang X, Zhang L, Teng M, Li X, 2020 Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation, Zhang W, Zeng F, Liu Y, Zhao Y, Lv H, Niu L, Teng M, Li X, 2013 A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions, Wang Q, Bian X, Zeng L, Pan F, Liu L, Liang J, Wang L, Zhou K, Lee W, Xiang Y, Li S, Teng M, Li X, Guo X, Zhang Y, 2020 Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins, Zhu Y, Wu B, Zhang X, Fan X, Niu L, Li X, Wang J, Teng M, 2015

Areas of Focus

Structural basis of protein-nucleic acid interactions
Regulatory mechanisms of Staphylococcus aureus biofilm formation
Cyanobacterial metabolic pathway modification and industrial application
Enzyme discovery, modification, and industrial application

Publications

Interface switch mediates signal transmission in a two-component system, Wang M, Guo Q, Zhu K, Fang B, Yang Y, Teng M, Li X*, Tao Y*, 2020
Structural and Functional Basis of Difructose Anhydride III Hydrolase, Which Sequentially Converts Inulin Using the Same Catalytic Residue, Yu S, Shen H, Cheng Y, Zhu Y, Li X*, Mu W*, 2018
Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode, Liu Z, Chen P, Wang X, Cai G, Niu L, Teng M*, Li X*, 2014
Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate, Shao Z, Yan W, Peng J, Zuo X, Zou Y, Li F, Gong D, Ma R, Wu J, Shi Y, Zhang Z, Teng M, Li X*, Gong Q*, 2014
The structural mechanism for the nucleoside tri- and di-phosphate hydrolysis activity of Ntdp from Staphylococcus aureus, Wang Z, Shen H, He B, Teng M*, Guo Q*, Li X*, 2021
Caulobacter crescentus β sliding clamp employs a noncanonical regulatory model of DNA replication, Jiang X, Zhang L, An J, Wang M, Teng M*, Guo Q*, Li X*, 2020
Antibiotic binding releases autoinhibition of the TipA multidrug-resistance transcriptional regulator, Jiang X*, Zhang L, Teng M, Li X*, 2020
Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation, Zhang W, Zeng F, Liu Y, Zhao Y, Lv H, Niu L, Teng M*, Li X*, 2013
A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions, Wang Q, Bian X, Zeng L, Pan F, Liu L, Liang J, Wang L, Zhou K, Lee W, Xiang Y, Li S, Teng M, Li X*, Guo X*, Zhang Y*, 2020
Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins, Zhu Y, Wu B, Zhang X, Fan X, Niu L, Li X*, Wang J*, Teng M*, 2015

Protein Nucleic Acid Interaction Structure Biofilm Regulation Staphylococcus Aureus Cyanobacteria Metabolic Pathway Enzyme

Luyan Ma - University of Chinese Academy of Sciences

Jiaohong Zhao - Shanghai Normal University

Zhihui He - Shanghai Normal University

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