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Xuan Zhang
Life Science
University of Science and Technology of China
Anhui
Language: English, Chinese
Centromere
Kinetochore
Assembly
Regulation
Histone
Post-Translational
Modification
Recognition
Staphylococcus Aureus
Pathogenic
Areas of Focus
- Centromere-kinetochore assembly and regulation mechanisms
- Recognition and regulation mechanisms of histone post-translational modifications
- Pathogenic mechanisms of Staphylococcus aureus
Work Experience
- 2011-2015 - Postdoctoral Research: Cornell University, Department of Biochemistry
- 2015-2019 - Special Associate Researcher: School of Life Sciences, University of Science and Technology of China
- 2019-Present - Associate Professor: School of Life Sciences, University of Science and Technology of China
Academic Background & Achievements
- 2005 - Bachelor of Science: Anhui University
- 2010 - Doctor of Science: University of Science and Technology of China
- Published in journals like Nature Communications, JACS, PNAS, Cell Research
Publications
- Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein, Fang Tiantian, Chen Wanbiao, Sheng Yaping, Yuan Siming, Tang Qiaowei, Li Gongyu, Huang Guangming, Su Jihu, Zhang Xuan, Zang Jianye, Liu Yangzhong, 2019
- Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides, Hang Tianrong, Chen Wanbiao, Wu Minhao, Zhan Li, Wang Chengliang, Jia Nan, Zhang Xuan, Zang Jianye, 2019
- Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore, Tian Tian, Li Xiaorun, Liu Yingying, Wang Chengliang, Liu Xing, Bi Guoqiang, Zhang Xuan, Yao Xiaobiao, Zhou Z.Hong, Zang Jianye, 2018
- Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis, Zhou Xing, Zheng Fan, Wang Chengliang, Wu Minhao, Zhang Xiaozhen, Wang Qian, Yao Xuebiao, Fu Chuanhai, Zhang Xuan, Zang Jianye, 2017
- Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion, Zhang Yingjie, Wu Minhao, Hang Tianrong, Wang Chengliang, Yang Ye, Pan Wenmin, Zang Jianye, Zhang Min, Zhang Xuan, 2017
- From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis, Eser Bekir E., Zhang Xuan, Chanani Prem K., Begley Tadhg P., Ealick Steven E., 2016
- Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis, Sasaki Eita, Zhang Xuan, Sun He G., Lu Mei-Yeh Jade, Liu Tsung-lin, Ou Albert, Li Jeng-yi, Chen Yu-hsiang, Ealick Steven E., Liu Hung-wen, 2014
