Professor | Xuan Zhang | Asia Growth Partners

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Name	Xuan Zhang
Contact Information	xuanzbin@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Xuan Zhang

Contact Information

xuanzbin@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	2005 - Bachelor of Science: Anhui University 2010 - Doctor of Science: University of Science and Technology of China Published in journals like Nature Communications, JACS, PNAS, Cell Research
Work Experience	2011-2015 - Postdoctoral Research: Cornell University, Department of Biochemistry 2015-2019 - Special Associate Researcher: School of Life Sciences, University of Science and Technology of China 2019-Present - Associate Professor: School of Life Sciences, University of Science and Technology of China

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

2005 - Bachelor of Science: Anhui University
2010 - Doctor of Science: University of Science and Technology of China
Published in journals like Nature Communications, JACS, PNAS, Cell Research

Work Experience

2011-2015 - Postdoctoral Research: Cornell University, Department of Biochemistry
2015-2019 - Special Associate Researcher: School of Life Sciences, University of Science and Technology of China
2019-Present - Associate Professor: School of Life Sciences, University of Science and Technology of China

Areas of Focus	Centromere-kinetochore assembly and regulation mechanisms Recognition and regulation mechanisms of histone post-translational modifications Pathogenic mechanisms of Staphylococcus aureus
Publications	Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein, Fang Tiantian, Chen Wanbiao, Sheng Yaping, Yuan Siming, Tang Qiaowei, Li Gongyu, Huang Guangming, Su Jihu, Zhang Xuan, Zang Jianye, Liu Yangzhong, 2019 Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides, Hang Tianrong, Chen Wanbiao, Wu Minhao, Zhan Li, Wang Chengliang, Jia Nan, Zhang Xuan, Zang Jianye, 2019 Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore, Tian Tian, Li Xiaorun, Liu Yingying, Wang Chengliang, Liu Xing, Bi Guoqiang, Zhang Xuan, Yao Xiaobiao, Zhou Z.Hong, Zang Jianye, 2018 Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis, Zhou Xing, Zheng Fan, Wang Chengliang, Wu Minhao, Zhang Xiaozhen, Wang Qian, Yao Xuebiao, Fu Chuanhai, Zhang Xuan, Zang Jianye, 2017 Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion, Zhang Yingjie, Wu Minhao, Hang Tianrong, Wang Chengliang, Yang Ye, Pan Wenmin, Zang Jianye, Zhang Min, Zhang Xuan, 2017 From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis, Eser Bekir E., Zhang Xuan, Chanani Prem K., Begley Tadhg P., Ealick Steven E., 2016 Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis, Sasaki Eita, Zhang Xuan, Sun He G., Lu Mei-Yeh Jade, Liu Tsung-lin, Ou Albert, Li Jeng-yi, Chen Yu-hsiang, Ealick Steven E., Liu Hung-wen, 2014

Areas of Focus

Centromere-kinetochore assembly and regulation mechanisms
Recognition and regulation mechanisms of histone post-translational modifications
Pathogenic mechanisms of Staphylococcus aureus

Publications

Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein, Fang Tiantian, Chen Wanbiao, Sheng Yaping, Yuan Siming, Tang Qiaowei, Li Gongyu, Huang Guangming, Su Jihu, Zhang Xuan, Zang Jianye, Liu Yangzhong, 2019
Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides, Hang Tianrong, Chen Wanbiao, Wu Minhao, Zhan Li, Wang Chengliang, Jia Nan, Zhang Xuan, Zang Jianye, 2019
Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore, Tian Tian, Li Xiaorun, Liu Yingying, Wang Chengliang, Liu Xing, Bi Guoqiang, Zhang Xuan, Yao Xiaobiao, Zhou Z.Hong, Zang Jianye, 2018
Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis, Zhou Xing, Zheng Fan, Wang Chengliang, Wu Minhao, Zhang Xiaozhen, Wang Qian, Yao Xuebiao, Fu Chuanhai, Zhang Xuan, Zang Jianye, 2017
Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion, Zhang Yingjie, Wu Minhao, Hang Tianrong, Wang Chengliang, Yang Ye, Pan Wenmin, Zang Jianye, Zhang Min, Zhang Xuan, 2017
From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis, Eser Bekir E., Zhang Xuan, Chanani Prem K., Begley Tadhg P., Ealick Steven E., 2016
Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis, Sasaki Eita, Zhang Xuan, Sun He G., Lu Mei-Yeh Jade, Liu Tsung-lin, Ou Albert, Li Jeng-yi, Chen Yu-hsiang, Ealick Steven E., Liu Hung-wen, 2014

Centromere Kinetochore Assembly Regulation Histone Post-Translational Modification Recognition Staphylococcus Aureus Pathogenic

Shanjin Huang - Tsinghua University

Yan Kaige - Southern University of Science and Technology

Shanjin Huang - Tsinghua University

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