Professor | Qinghua Shi | Asia Growth Partners

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Name	Qinghua Shi
Contact Information	qshi@ustc.edu.cn
Language ability	English, Chinese, German
Province	Anhui

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Name

Qinghua Shi

Contact Information

qshi@ustc.edu.cn

Language ability

English, Chinese, German

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	1994-09 to 1998-10: PhD from German National Research Center for Environment and Health and Nanjing Normal University National Outstanding Youth Fund recipient Chief Scientist of National Major Scientific Research Program
Work Experience	1998-11 to 2001-12: Postdoctoral Fellow at University of Calgary, Canada 2002-01 to 2004-12: Research Fellow at Harvard Medical School, USA 2004-12 to present: Professor and PI at University of Science and Technology of China
Awards	National Outstanding Youth Fund recipient Chief Scientist of National Major Scientific Research Program

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

1994-09 to 1998-10: PhD from German National Research Center for Environment and Health and Nanjing Normal University
National Outstanding Youth Fund recipient
Chief Scientist of National Major Scientific Research Program

Work Experience

1998-11 to 2001-12: Postdoctoral Fellow at University of Calgary, Canada
2002-01 to 2004-12: Research Fellow at Harvard Medical School, USA
2004-12 to present: Professor and PI at University of Science and Technology of China

Awards

National Outstanding Youth Fund recipient
Chief Scientist of National Major Scientific Research Program

Areas of Focus	Molecular basis of human sperm and egg development disorders Molecular regulation of meiosis Directed differentiation of stem cells into sperm Molecular mechanisms of follicle formation and initiation of development Pathways and fate of tumor cells
Publications	A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation., Fan S, Y Wang, H Jiang, X Jiang, J Zhou, Y Jiao, J Ye, Z Xu, Y Wang, X Xie, H Zhang, Y Li, W Liu, X Zhang, H Ma, B Shi, Y Zhang, M Zubair, W Shah, Z Xu, B Xu and Shi Q (史庆华), 2023 RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes., Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, Jiang H, Fan S, Zhang H, Shi B, Zhang B, Jiang X, Li Y, Zhou J, Xu J, Zhang X, Hou X, Yin H, Zhang Y, and Shi Q (史庆华), 2022 Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans., Fan S, Y Jiao, R Khan, X Jiang, A R Javed, A Ali, H Zhang, J Zhou, M Naeem, G Murtaza, Y Li, G Yang, Q Zaman, M Zubair, H Guan, X Zhang, H Ma, H Jiang, H Ali, S Dil, W Shah, N Ahmad, Y Zhang and Shi Q (史庆华), 2021 A DNAH17 Missense Variant Causes Flagella Destabilization and Asthenozoospermia., Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao JN, Zhou JT, Li Y……Zhang Y, Shi Q (史庆华), 2020 A homozygous FANCM frameshift pathogenic variant causes male infertility., Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y , Shi Q (史庆华), 2019 RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice., Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y , Shi Q (史庆华), 2017 DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data., Zhang Y, Zang Q, Zhang H, Ban R, Yang Y, Iqbal F, Li A, Shi Q (史庆华), 2016 DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data., Zhang Y, Yu Z, Ban R, Zhang H, Iqbal F, Zhao A, Li A , Shi Q (史庆华), 2015 SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining., Zhang Y, Zhong L, Xu B, Yang Y, Ban R, Zhu J, Cooke HJ, Hao Q, Shi Q (史庆华), 2013 Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines., Shi Q (史庆华), King RW, 2005

Areas of Focus

Molecular basis of human sperm and egg development disorders
Molecular regulation of meiosis
Directed differentiation of stem cells into sperm
Molecular mechanisms of follicle formation and initiation of development
Pathways and fate of tumor cells

Publications

A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation., Fan S, Y Wang, H Jiang, X Jiang, J Zhou, Y Jiao, J Ye, Z Xu, Y Wang, X Xie, H Zhang, Y Li, W Liu, X Zhang, H Ma, B Shi, Y Zhang, M Zubair, W Shah, Z Xu*, B Xu* and Shi Q (史庆华)*, 2023
RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes., Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, Jiang H, Fan S, Zhang H, Shi B, Zhang B, Jiang X, Li Y, Zhou J, Xu J, Zhang X, Hou X, Yin H, Zhang Y*, and Shi Q (史庆华)*, 2022
Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans., Fan S, Y Jiao, R Khan, X Jiang, A R Javed, A Ali, H Zhang, J Zhou, M Naeem, G Murtaza, Y Li, G Yang, Q Zaman, M Zubair, H Guan, X Zhang, H Ma, H Jiang, H Ali, S Dil, W Shah, N Ahmad, Y Zhang and Shi Q (史庆华)*, 2021
A DNAH17 Missense Variant Causes Flagella Destabilization and Asthenozoospermia., Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao JN, Zhou JT, Li Y……Zhang Y*, Shi Q (史庆华)*, 2020
A homozygous FANCM frameshift pathogenic variant causes male infertility., Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y *, Shi Q (史庆华)*, 2019
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice., Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y *, Shi Q (史庆华)*, 2017
DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data., Zhang Y, Zang Q, Zhang H, Ban R, Yang Y, Iqbal F, Li A*, Shi Q (史庆华)*, 2016
DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data., Zhang Y, Yu Z, Ban R, Zhang H, Iqbal F, Zhao A, Li A *, Shi Q (史庆华)*, 2015
SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining., Zhang Y, Zhong L, Xu B, Yang Y, Ban R, Zhu J, Cooke HJ, Hao Q, Shi Q (史庆华)*, 2013
Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines., Shi Q (史庆华), King RW*, 2005

Sperm Egg Molecular Meiosis Stem Cells Differentiation Follicle Tumor Pathways Fate

Jun Xu - Peking University

Cheng-Ran Xu - Peking University

Shuping Peng - Central South University

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