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Qinghua Shi
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: English, Chinese, German
Sperm
Egg
Molecular
Meiosis
Stem Cells
Differentiation
Follicle
Tumor
Pathways
Fate
Areas of Focus
- Molecular basis of human sperm and egg development disorders
- Molecular regulation of meiosis
- Directed differentiation of stem cells into sperm
- Molecular mechanisms of follicle formation and initiation of development
- Pathways and fate of tumor cells
Work Experience
- 1998-11 to 2001-12: Postdoctoral Fellow at University of Calgary, Canada
- 2002-01 to 2004-12: Research Fellow at Harvard Medical School, USA
- 2004-12 to present: Professor and PI at University of Science and Technology of China
Academic Background & Achievements
- 1994-09 to 1998-10: PhD from German National Research Center for Environment and Health and Nanjing Normal University
- National Outstanding Youth Fund recipient
- Chief Scientist of National Major Scientific Research Program
Publications
- A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation., Fan S, Y Wang, H Jiang, X Jiang, J Zhou, Y Jiao, J Ye, Z Xu, Y Wang, X Xie, H Zhang, Y Li, W Liu, X Zhang, H Ma, B Shi, Y Zhang, M Zubair, W Shah, Z Xu*, B Xu* and Shi Q (史庆华)*, 2023
- RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes., Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, Jiang H, Fan S, Zhang H, Shi B, Zhang B, Jiang X, Li Y, Zhou J, Xu J, Zhang X, Hou X, Yin H, Zhang Y*, and Shi Q (史庆华)*, 2022
- Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans., Fan S, Y Jiao, R Khan, X Jiang, A R Javed, A Ali, H Zhang, J Zhou, M Naeem, G Murtaza, Y Li, G Yang, Q Zaman, M Zubair, H Guan, X Zhang, H Ma, H Jiang, H Ali, S Dil, W Shah, N Ahmad, Y Zhang and Shi Q (史庆华)*, 2021
- A DNAH17 Missense Variant Causes Flagella Destabilization and Asthenozoospermia., Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao JN, Zhou JT, Li Y……Zhang Y*, Shi Q (史庆华)*, 2020
- A homozygous FANCM frameshift pathogenic variant causes male infertility., Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y *, Shi Q (史庆华)*, 2019
- RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice., Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y *, Shi Q (史庆华)*, 2017
- DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data., Zhang Y, Zang Q, Zhang H, Ban R, Yang Y, Iqbal F, Li A*, Shi Q (史庆华)*, 2016
- DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data., Zhang Y, Yu Z, Ban R, Zhang H, Iqbal F, Zhao A, Li A *, Shi Q (史庆华)*, 2015
- SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining., Zhang Y, Zhong L, Xu B, Yang Y, Ban R, Zhu J, Cooke HJ, Hao Q, Shi Q (史庆华)*, 2013
- Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines., Shi Q (史庆华), King RW*, 2005
Awards
- National Outstanding Youth Fund recipient
- Chief Scientist of National Major Scientific Research Program
