Professor | Guoliang Cui | Asia Growth Partners

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Name	Guoliang Cui
Contact Information	gcui@ustc.edu.cn
Language ability	Chinese, English, German
Province	Anhui

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Name

Guoliang Cui

Contact Information

gcui@ustc.edu.cn

Language ability

Chinese, English, German

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2001-2005 Bachelor's Degree: Shandong University 2005-2010 Doctorate: Shanghai Institute of Nutrition, Chinese Academy of Sciences
Work Experience	2010-2012 - GlaxoSmithKline China R&D Center - Research Fellow 2012-2016 - Yale University, USA - Postdoctoral Researcher 2016-2021 - German Cancer Research Center (DKFZ) - Tenure-track Researcher 2021-2023 - German Cancer Research Center (DKFZ) - Permanent Researcher, Head of Division 2023-2024 - Hefei Comprehensive National Science Center - Senior Researcher 2024-present - University of Science and Technology of China - Professor
Awards	2016: Helmholtz Young Investigator Award by Helmholtz Association 2020: Georges-Köhler Award by German Society for Immunology 2021: Lloyd J. Old STAR Award by Cancer Research Institute, New York 2021: EMBO Young Investigator Program (EMBO YIP) 2022: ERC Consolidator Award by European Research Council 2024: National Distinguished Young Scholar

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2001-2005 Bachelor's Degree: Shandong University
2005-2010 Doctorate: Shanghai Institute of Nutrition, Chinese Academy of Sciences

Work Experience

2010-2012 - GlaxoSmithKline China R&D Center - Research Fellow
2012-2016 - Yale University, USA - Postdoctoral Researcher
2016-2021 - German Cancer Research Center (DKFZ) - Tenure-track Researcher
2021-2023 - German Cancer Research Center (DKFZ) - Permanent Researcher, Head of Division
2023-2024 - Hefei Comprehensive National Science Center - Senior Researcher
2024-present - University of Science and Technology of China - Professor

Awards

2016: Helmholtz Young Investigator Award by Helmholtz Association
2020: Georges-Köhler Award by German Society for Immunology
2021: Lloyd J. Old STAR Award by Cancer Research Institute, New York
2021: EMBO Young Investigator Program (EMBO YIP)
2022: ERC Consolidator Award by European Research Council
2024: National Distinguished Young Scholar

Areas of Focus	Metabolic mechanisms of T cell differentiation Development of novel immunotherapeutic drug targets for cancer and infection
Publications	Serine enrichment in tumor promotes regulatory T cell accumulation through sphinganine., Sicong Ma, Roger Sandhoff, Xiu Luo, Fuwei Shang, Qiaozhen Shi, Zhaolong Li, Jingxia Wu, Yanan Ming, Frank Schwarz, Alaa Madi, Nina Weisshaar, Alessa Mieg, Marvin Hering, Xin Yan, Kerstin Mohr, Nora ten Bosch, Zhe Li, Gernot Poschet, Hans-Reimer Rodewald, Nina Papavasiliou, Xi Wang, Pu Gao & Guoliang Cui, 2024 The malate shuttle detoxifies ammonia in exhausted T cells by producing 2-ketoglutarate., Nina Weisshaar, Sicong Ma, Yanan Ming, Alaa Madi, Alessa Mieg, Marvin Hering, Ferdinand Zettl, Kerstin Mohr, Nora Ten Bosch, Diana Stichling, Michael Buettner, Gernot Poschet, Glynis Klinke, Michael Schulz, Nina Kunze-Rohrbach, Carolin Kerber, Isabel Madeleine Klein, Jingxia Wu, Xi Wang & Guoliang Cui, 2023 Rgs16 promotes antitumor CD8+ T cell exhaustion., Nina Weisshaar, Jingxia Wu, Yanan Ming, Alaa Madi, Agnes Hotz-Wagenblatt, Sicong Ma, Alessa Mieg, Marvin Hering, Ferdinand Zettl, Kerstin Mohr, Tilo Schlimbach, Nora Ten Bosch, Franziska Hertel, Lisann Müller, Hannah Byren, Mona Wang, Helena Borgers, Mareike Munz, Lukas Schmitt, Franciscus van der Hoeven, Ulrich Kloz, Rafael Carretero, Nikolai Schleußner, Rene-Filip Jackstadt, Ilse Hofmann & Guoliang Cui, 2022 Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors., Shihao Xu, Omkar Chaudhary, Patricia Rodríguez-Morales, Xiaoli Sun, Dan Chen, Roberta Zappasodi, Ziyan Xu, Antonio F. M. Pinto, April Williams, Isabell Schulze, Yagmur Farsakoglu, Siva Karthik Varanasi, Jun Siong Low, Wenxi Tang, Haiping Wang, Bryan McDonald, Victoria Tripple, Michael Downes, Ronald M. Evans, Nada A. Abumrad, Taha Merghoub, Jedd D. Wolchok, Maxim N. Shokhirev, Ping-Chih Ho, Joseph L. Witztum, Brinda Emu, Guoliang Cui & Susan M. Kaech, 2021 Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness., Jingxia Wu, Sicong Ma, Roger Sandhoff, Yanan Ming, Agnes Hotz-Wagenblatt, Vincent Timmerman, Nathalie Bonello-Palot, Beate Schlotter-Weigel, Michaela Auer-Grumbach, Pavel Seeman, Wolfgang N. Löscher, Markus Reindl, Florian Weiss, Eric Mah, Nina Weisshaar, Alaa Madi, Kerstin Mohr, Tilo Schlimbach, Rubí M. H. Velasco Cárdenas, Jonas Koeppel, Florian Grünschläger, Lisann Müller, Maren Baumeister, Britta Brügger, Michael Schmitt, Guido Wabnitz, Yvonne Samstag & Guoliang Cui, 2019

Areas of Focus

Metabolic mechanisms of T cell differentiation
Development of novel immunotherapeutic drug targets for cancer and infection

Publications

Serine enrichment in tumor promotes regulatory T cell accumulation through sphinganine., Sicong Ma, Roger Sandhoff, Xiu Luo, Fuwei Shang, Qiaozhen Shi, Zhaolong Li, Jingxia Wu, Yanan Ming, Frank Schwarz, Alaa Madi, Nina Weisshaar, Alessa Mieg, Marvin Hering, Xin Yan, Kerstin Mohr, Nora ten Bosch, Zhe Li, Gernot Poschet, Hans-Reimer Rodewald, Nina Papavasiliou, Xi Wang, Pu Gao & Guoliang Cui, 2024
The malate shuttle detoxifies ammonia in exhausted T cells by producing 2-ketoglutarate., Nina Weisshaar, Sicong Ma, Yanan Ming, Alaa Madi, Alessa Mieg, Marvin Hering, Ferdinand Zettl, Kerstin Mohr, Nora Ten Bosch, Diana Stichling, Michael Buettner, Gernot Poschet, Glynis Klinke, Michael Schulz, Nina Kunze-Rohrbach, Carolin Kerber, Isabel Madeleine Klein, Jingxia Wu, Xi Wang & Guoliang Cui, 2023
Rgs16 promotes antitumor CD8+ T cell exhaustion., Nina Weisshaar, Jingxia Wu, Yanan Ming, Alaa Madi, Agnes Hotz-Wagenblatt, Sicong Ma, Alessa Mieg, Marvin Hering, Ferdinand Zettl, Kerstin Mohr, Tilo Schlimbach, Nora Ten Bosch, Franziska Hertel, Lisann Müller, Hannah Byren, Mona Wang, Helena Borgers, Mareike Munz, Lukas Schmitt, Franciscus van der Hoeven, Ulrich Kloz, Rafael Carretero, Nikolai Schleußner, Rene-Filip Jackstadt, Ilse Hofmann & Guoliang Cui, 2022
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors., Shihao Xu, Omkar Chaudhary, Patricia Rodríguez-Morales, Xiaoli Sun, Dan Chen, Roberta Zappasodi, Ziyan Xu, Antonio F. M. Pinto, April Williams, Isabell Schulze, Yagmur Farsakoglu, Siva Karthik Varanasi, Jun Siong Low, Wenxi Tang, Haiping Wang, Bryan McDonald, Victoria Tripple, Michael Downes, Ronald M. Evans, Nada A. Abumrad, Taha Merghoub, Jedd D. Wolchok, Maxim N. Shokhirev, Ping-Chih Ho, Joseph L. Witztum, Brinda Emu, Guoliang Cui & Susan M. Kaech, 2021
Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness., Jingxia Wu, Sicong Ma, Roger Sandhoff, Yanan Ming, Agnes Hotz-Wagenblatt, Vincent Timmerman, Nathalie Bonello-Palot, Beate Schlotter-Weigel, Michaela Auer-Grumbach, Pavel Seeman, Wolfgang N. Löscher, Markus Reindl, Florian Weiss, Eric Mah, Nina Weisshaar, Alaa Madi, Kerstin Mohr, Tilo Schlimbach, Rubí M. H. Velasco Cárdenas, Jonas Koeppel, Florian Grünschläger, Lisann Müller, Maren Baumeister, Britta Brügger, Michael Schmitt, Guido Wabnitz, Yvonne Samstag & Guoliang Cui, 2019

T Cells Metabolism Differentiation Cancer Infection Immunotherapy Drug Targets Gene Knockout Mouse Models Biomarkers

Lemin Zheng - Peking University

Yan Liu - Wuhan University

Zeng Zhaoyang - Central South University

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