Professor | Yajun Duan | Asia Growth Partners

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Name	Yajun Duan
Contact Information	yajunduan@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

Upload Avatar (500 x 500)

Name

Yajun Duan

Contact Information

yajunduan@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2000-2004 Bachelor of Science in Biological Sciences: Nankai University 2004-2009 Doctor of Science in Biochemistry and Molecular Biology: Nankai University Published over 100 SCI papers with 1443 citations
Work Experience	2009-2015 - Nankai University - Lecturer, Associate Researcher 2015-2021 - Hefei University of Technology - Professor 2021-present - University of Science and Technology of China - Professor
Awards	Tianjin Innovative Talent Promotion Plan - Outstanding Young Scientific Talent National Natural Science Foundation of China - Excellent Young Scientists Fund Second Prize in Natural Science of Higher Education Scientific Research Outstanding Achievement Award Third Prize in Chinese Medical Science and Technology Award

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2000-2004 Bachelor of Science in Biological Sciences: Nankai University
2004-2009 Doctor of Science in Biochemistry and Molecular Biology: Nankai University
Published over 100 SCI papers with 1443 citations

Work Experience

2009-2015 - Nankai University - Lecturer, Associate Researcher
2015-2021 - Hefei University of Technology - Professor
2021-present - University of Science and Technology of China - Professor

Awards

Tianjin Innovative Talent Promotion Plan - Outstanding Young Scientific Talent
National Natural Science Foundation of China - Excellent Young Scientists Fund
Second Prize in Natural Science of Higher Education Scientific Research Outstanding Achievement Award
Third Prize in Chinese Medical Science and Technology Award

Areas of Focus	Cardiovascular disease research Metabolic-driven atherosclerotic cardiovascular disease
Publications	Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia., Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, Chen S, Yang Y, Li J, Zhang S, Yin Z, Liang Y, Yan T, Yu M, Feng K, Zhao D, Yang X, Zhang X, Ma L, Iwakiri Y, Chen L, Tang X, Chen Y, Chen H, Duan Y., 2024 Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage., Gong K, Xue C, Feng Z, Pan R, Wang M, Chen S, Chen Y, Guan Y, Dai L, Zhang S, Jiang L, Li L, Wang B, Yin Z, Ma L, Iwakiri Y, Tang J, Liao C, Chen H, Duan Y., 2024 Liver ChREBP deficiency inhibits fructose-induced insulin resistance in pregnant mice and female offspring., Jiaqi Li, Shuang Zhang, Yuyao Sun, Jian Li, Zian Feng, Huaxin Li, Mengxue Zhang, Tengteng Yan, Jihong Han, Yajun Duan., 2024 Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms., Yang Y, Feng K, Yuan L, Liu Y, Zhang M, Guo K, Yin Z, Wang W, Zhou S, Sun H, Yan K, Yan X, Wang X, Duan Y, Hu Y, Han J., 2023 Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics., Duan Y, Gong K, Xu S, Zhang F, Meng X, Han J., 2022 NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity., Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, Wei Z, Yang X, Chen Y, Li X, Liao C, Han J, Miao QR, Duan Y., 2021 Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances LXR anti-tumorigenic actions and removes LXR-induced lipogenesis., Feng K, Ma C, Liu Y, Yang X, Yang Z, Chen Y, Xu T, Yang C, Zhang S, Li Q, Wei Z, Zhao D, Zeng P, Han J, Gao J, Chen Y, Duan Y., 2021 Reduction of Nogo-B expression deficiency protects mice against high-carbohydrate diet-induced hepatic metabolic disorders by regulating ChREBP and insulin activity., Zhang S, Guo F, Yu M, Yang X, Yao Z, Li Q, Wei Z, Feng K, Zeng P, Zhao D, Li X, Zhu Y, Miao QR, Iwakiri Y, Chen Y, Han J, Duan Y., 2020 Rosiglitazone alleviates a-naphthylisothiocyanate-induced intrahepatic cholestasis in mice – The role of circulating 15d-PGJ2 and Nogo., Zhang S, Yu M, Guo F, Yang X, Chen Y, Ma C, Li Q, Wei Z, Li X, Wang H, Hu H, Zhang Y, Kong D, Miao Q, Hu W, Hajjar DP, Zhu Y, Han J, Duan Y., 2020 Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression., Wang D, Yang X, Chen Y, Gong K, Yu M, Gao Y, Wu X, Hu H, Liao C, Han J, Duan Y., 2020

Areas of Focus

Cardiovascular disease research
Metabolic-driven atherosclerotic cardiovascular disease

Publications

Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia., Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, Chen S, Yang Y, Li J, Zhang S, Yin Z, Liang Y, Yan T, Yu M, Feng K, Zhao D, Yang X, Zhang X, Ma L, Iwakiri Y, Chen L, Tang X, Chen Y, Chen H, Duan Y., 2024
Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage., Gong K, Xue C, Feng Z, Pan R, Wang M, Chen S, Chen Y, Guan Y, Dai L, Zhang S, Jiang L, Li L, Wang B, Yin Z, Ma L, Iwakiri Y, Tang J, Liao C, Chen H, Duan Y., 2024
Liver ChREBP deficiency inhibits fructose-induced insulin resistance in pregnant mice and female offspring., Jiaqi Li, Shuang Zhang, Yuyao Sun, Jian Li, Zian Feng, Huaxin Li, Mengxue Zhang, Tengteng Yan, Jihong Han, Yajun Duan., 2024
Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms., Yang Y, Feng K, Yuan L, Liu Y, Zhang M, Guo K, Yin Z, Wang W, Zhou S, Sun H, Yan K, Yan X, Wang X, Duan Y, Hu Y, Han J., 2023
Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics., Duan Y, Gong K, Xu S, Zhang F, Meng X, Han J., 2022
NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity., Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, Wei Z, Yang X, Chen Y, Li X, Liao C, Han J, Miao QR, Duan Y., 2021
Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances LXR anti-tumorigenic actions and removes LXR-induced lipogenesis., Feng K, Ma C, Liu Y, Yang X, Yang Z, Chen Y, Xu T, Yang C, Zhang S, Li Q, Wei Z, Zhao D, Zeng P, Han J, Gao J, Chen Y, Duan Y., 2021
Reduction of Nogo-B expression deficiency protects mice against high-carbohydrate diet-induced hepatic metabolic disorders by regulating ChREBP and insulin activity., Zhang S, Guo F, Yu M, Yang X, Yao Z, Li Q, Wei Z, Feng K, Zeng P, Zhao D, Li X, Zhu Y, Miao QR, Iwakiri Y, Chen Y, Han J, Duan Y., 2020
Rosiglitazone alleviates a-naphthylisothiocyanate-induced intrahepatic cholestasis in mice – The role of circulating 15d-PGJ2 and Nogo., Zhang S, Yu M, Guo F, Yang X, Chen Y, Ma C, Li Q, Wei Z, Li X, Wang H, Hu H, Zhang Y, Kong D, Miao Q, Hu W, Hajjar DP, Zhu Y, Han J, Duan Y., 2020
Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression., Wang D, Yang X, Chen Y, Gong K, Yu M, Gao Y, Wu X, Hu H, Liao C, Han J, Duan Y., 2020

Cardiovascular Disease Research Metabolism Atherosclerosis Organ Interaction Mechanism Clinical Prevention Treatment

Er Dan Dong - Peking University

Xian Wang - Peking University

Kong Wei - Peking University

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