Upload Avatar (500 x 500)
Xuejuan Wang
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: English, Chinese
Dna
Double-Strand Breaks
Signal Transduction
Molecular Mechanisms
Meiotic Synaptonemal Complexes
Dynamic Assembly
Cryogenic Electron Microscopy
Genomic Stability
Kinase Regulation
Biomolecular Complexes
Areas of Focus
- Molecular mechanisms of early signal transduction in DNA double-strand breaks (DSB) and dynamic assembly of meiotic synaptonemal complexes
Work Experience
- 2010 - Present: Research Assistant, Assistant Researcher, Specially Appointed Associate Researcher, and Researcher at University of Science and Technology of China
Academic Background & Achievements
- Bachelor's degree: Fudan University
- Master's degree: San Diego State University
- Doctorate: Nanjing Agricultural University
- Published 10 papers as first/corresponding author in high-impact journals like Science, Nature Communications, and Cell Research
Publications
- Structural basis of allosteric regulation of Tel1/ATM kinase, Xin, J., Xu, Z., Wang, X., Tian Y., Zhang, Z. and Cai, G., 2019
- Structure and Functional Interactions of INO80 Actin/Arp Module, Zhang, X., Wang, X., Zhang, Z. and Cai, G., 2018
- Modulation of Fatty Acid Synthase by ATR checkpoint kinase Rad3, Qiu, S., Liu, S., Zaoti, Z., Wang, X., Cai, G., 2019
- Preparation of endogenous TopBP1/Dpb11 and effect on central checkpoint kinase Mec1- Ddc2 (human ATR-ATRIP homolog), Wu, T., Zhang, Z., Wang, X., 2019
- Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex, Wang, X., Ahmad, S., Zhang, Z., Côté, J., Cai, G., 2018
- Architecture of SWI/SNF chromatin remodeling complex, Zhang, Z., Wang, X., Xin, J., Ding, Z., Liu, S., Fang, Q., Yang, N., Xu, R., Cai, G., 2018
- 3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP, Wang, X., Ran, T., Zhang, X., Xin, J., Zhang, Z., Wu, T., Wang, W. and Cai, G., 2017
- Structure of the intact ATM/Tel1 kinase, Wang, X., Chu, H., Lv, M., Zhang, Z., Qiu, S., Liu, H., Shen, X., Wang, W., Cai, G., 2016
- Redefining the Modular Organization of the Core Mediator Complex, Wang, X., Sun, Q., Ding, Z., Ji, J., Wang, J., Kong, X., Yang J.H., and Cai, G., 2014
- Structural flexibility and functional interaction of mediator Cdk8 module, Wang, X., Wang, J., Ding, Z., Ji, J., Sun, Q., and Cai, G., 2013
- Structural insight into precursor tRNA processing by yeast ribonuclease P, Lan, P., Tan, M., Zhang, Y., Niu, S., Chen, J., Shi, S., Qiu, S., Wang, X., Peng, X., Cai, G., Cheng, H., Wu, J., Li, G., Lei, M., 2018
Awards
- 2019: National Natural Science Foundation of China 'Outstanding Youth Science Fund' project
- 2019: Anhui Province 'Outstanding Youth' project funding
