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Xiaohu Zheng
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: Chinese, English
Nk Cells
Tumor
Immune Microenvironment
Inflammation
Immune Intervention
Synthetic Biology
Immunotherapy
Molecular Creation
Cancer
Autoimmune
Areas of Focus
- NK cells and tumor immune microenvironment
- Discovery of tumor/autoimmune inflammation immune intervention targets
- Creation of new molecules for immunotherapy using synthetic biology concepts
Academic Background & Achievements
- 2015 - PhD: University of Science and Technology of China
- National Excellent Young Scientist
- Anhui Province Outstanding Young Scientist
- Chief Scientist of the Chinese Academy of Sciences Leading Project
Publications
- Tumors evade immune cytotoxicity by altering the surface topology of NK cells., Xiaohu Zheng, Zhuanghao Hou, Yeben Qian, Yongwei Zhang, Quanwei Cui, Xuben Wang, Yiqing Shen, Zhenbang Liu, Yonggang Zhou, Binqing Fu, Rui Sun, Zhigang Tian, Guangming Huang, Haiming Wei, 2023
- J Hematol Oncol., Dong Wang, Xiaohui Li, Defeng Jiao, Ying Cai, Liting Qian, Yiqing Shen, Yichen Lu, Yonggang Zhou, Binqing Fu, Rui Sun, Zhigang Tian, Xiaohu Zheng, Haiming Wei, 2023
- Immunomagnetic microscopy of tumor tissues using quantum sensors in diamond., Sanyou Chen, Wanhe Li, Xiaohu Zheng, Pei Yu, Pengfei Wang, Ziting Sun, Yao Xu, Defeng Jiao, Xiangyu Ye, Mingcheng Cai, Mengze Shen, Mengqi Wang, Qi Zhang, Fei Kong, Ya Wang, Jie He, Haiming Wei, Fazhan Shi, Jiangfeng Du, 2022
- The use of supercytokines, immunocytokines, engager cytokines, and other synthetic cytokines in immunotherapy., Xiaohu Zheng, Yaqi Wu, Jiacheng Bi, Yingying Huang, Ying Cheng, Yangyang Li, Yuwei Wu, Guoshuai Cao, Zhigang Tian, 2021
- Rapamycin pretreatment rescues the bone marrow AML cell elimination capacity of CAR-T cells., Zhigang Nian, Xiaohu Zheng, Yingchao Dou, Xianghui Du, Li Zhou, Binqing Fu, Rui Sun, Zhigang Tian, Haiming Wei, 2021
- Increased expression of adenosine A3 receptor in tumor-infiltrating natural killer cells., Jiacheng Bi, Chaoyue Zheng, Xiaohu Zheng, 2021
- Pathogenic T cells and inflammatory monocytes incite inflammatory storm in severe COVID-19 patients., Yonggang Zhou, Binqing Fu, Xiaohu Zheng, Dongsheng Wang, Changcheng Zhao, Yingjie Qi, Rui Sun, Zhigang Tian, Xiaoling Xu, Haiming Wei, 2020
- Mitochondrial fragmentation limits natural killer cell-based tumour immunosurveillance., Xiaohu Zheng, Yeben Qian, Binqing Fu, Defeng Jiao, Yong Jiang, Peng Chen, Yiqing Shen, Huafeng Zhang, Rui Sun, Zhigang Tian, Haiming Wei, 2019
- Peptidase inhibitor 15 as a novel blood diagnostic marker for cholangiocarcinoma., Yong Jiang, Xiaohu Zheng, Defeng Jiao, Peng Chen, Yechuan Xu, Haiming Wei, Yeben Qian, 2019
- EpCAM inhibition sensitizes chemoresistant leukemia to immune surveillance., Xiaohu Zheng, Fan X, Fu B, Zheng M, Zhang A, Zhong K, Yan J, Sun R, Tian Z, Wei H, 2017
- Targeting LunX inhibits non-small-cell lung cancer growth and metastasis., Xiaohu Zheng, Min Cheng, Binqing Fu, Xiaolei Fan, Qing Wang, Xiaoqing Yu, Rui Sun, Zhigang Tian, Haiming Wei, 2015
- Lung specific X protein as a novel therapeutic target for lung cancer., Xiaohu Zheng, Zhigang Tian, Haiming Wei, 2015
Awards
- Young Scholar Award of the Chinese Society of Immunology
