Professor | Hui Ma | Asia Growth Partners

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Name	Hui Ma
Contact Information	clsmh@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Hui Ma

Contact Information

clsmh@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2006-2010 Bachelor: Zhejiang University, School of Life Sciences 2010-2014 PhD: National University of Singapore, School of Medicine Received funding from National Natural Science Foundation of China
Work Experience	2014-2015 - National University of Singapore, School of Medicine - Research Assistant 2015-2017 - University of Science and Technology of China, School of Life Sciences - Postdoctoral Researcher 2017-2022 - University of Science and Technology of China, School of Life Sciences and Medicine - Special Associate Researcher 2022-present - University of Science and Technology of China, School of Life Sciences and Medicine - Associate Researcher
Awards	National Natural Science Foundation of China General Program Youth Science Fund Postdoctoral Science Fund (First Class)

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2006-2010 Bachelor: Zhejiang University, School of Life Sciences
2010-2014 PhD: National University of Singapore, School of Medicine
Received funding from National Natural Science Foundation of China

Work Experience

2014-2015 - National University of Singapore, School of Medicine - Research Assistant
2015-2017 - University of Science and Technology of China, School of Life Sciences - Postdoctoral Researcher
2017-2022 - University of Science and Technology of China, School of Life Sciences and Medicine - Special Associate Researcher
2022-present - University of Science and Technology of China, School of Life Sciences and Medicine - Associate Researcher

Awards

National Natural Science Foundation of China General Program
Youth Science Fund
Postdoctoral Science Fund (First Class)

Areas of Focus	Molecular mechanisms of human spermatogenesis and maturation disorders Regulatory mechanisms of meiosis
Publications	M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination., Li Y, Wu Y, Khan I, Zhou J, Lu Y, Ye J, Liu J, Xie X, Hu C, Jiang H, Fan S, Zhang H, Zhang Y, Jiang X, Xu B, Ma H, Shi Q, 2023 RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes., Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, Jiang H, Fan S, Zhang H, Shi B, Zhang B, Jiang X, Li Y, Zhou J, Xu J, Zhang X, Hou X, Yin H, Zhang Y, Shi Q, 2022 ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression., Xu J, Gao J, Liu J, Huang X, Zhang H, Ma A, Ye J, Zhang X, Li Y, Yang G, Yin H, Khan R, Li T, Fan S, Jiang X, Ma H, Shi Q, 2022 Biallelic HFM1 variants cause non-obstructive azoospermia with meiotic arrest in humans by impairing crossover formation to varying degrees., Xie X, Murtaza G, Li Y, Zhou J, Ye J, Khan R, Jiang L, Khan I, Zubair M, Yin H, Jiang H, Liu W, Shi B, Hou X, Gong C, Fan S, Wang Y, Jiang X, Zhang Y, Zhang H, Ma H, Shi Q, 2022 Novel frameshift mutation in STK33 is associated with asthenozoospermia and multiple morphological abnormality of the flagella., Ma H, Zhang B, Khan A, Zhao D, Ma A, Jianteng Z, Khan I, Khan K, Zhang H, Zhang Y, Xiaohua J, Dil S, Zeb A, Rahim F, Shi Q, 2021 A DNAH17 missense variant causes destabilization of doublets 4-7 in flagella and asthenozoospermia., Zhang B, Ma H, Khan T, Li T, Zhang H, Gao J, Zhou J, Ma A, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain H. M. J., Khan R, Yousaf A, Yuan L, Lu Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q, 2020 A TOP6BL mutation abolishes meiotic DNA double-strand break formation and causes human infertility., Jiao Y, Fan S, Jabeen N, Zhang H, Khan R, Murtaza G, Jiang H, Ali A, Li Y, Bao J, Zhang B, Xu J, Xu B, Hussain HMJ, Zaman Q, Khan I, Bukhari I, Iqbal F, Yousaf A, Dil S, Khan M, Ahmad N, Ma H, Jiang X, Zhang Y, Shi Q, 2020 The testis specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis., Gao Q, Khan R, Yu C, Alsheimer M, Jiang X, Ma H, Shi Q, 2020 A homozygous FANCM frameshift pathogenic variant causes male infertility., Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y, Shi Q, 2019 Zfp322a regulates mouse ES cell pluripotency and enhances reprogramming efficiency., Ma H, Ng HM, Teh X, Li H, Lee YH, Chong YM, Loh YH, Collins JJ, Feng B, Yang H, Wu Q, 2014

Areas of Focus

Molecular mechanisms of human spermatogenesis and maturation disorders
Regulatory mechanisms of meiosis

Publications

M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination., Li Y, Wu Y, Khan I, Zhou J, Lu Y, Ye J, Liu J, Xie X, Hu C, Jiang H, Fan S, Zhang H, Zhang Y, Jiang X, Xu B, Ma H, Shi Q, 2023
RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes., Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, Jiang H, Fan S, Zhang H, Shi B, Zhang B, Jiang X, Li Y, Zhou J, Xu J, Zhang X, Hou X, Yin H, Zhang Y, Shi Q, 2022
ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression., Xu J, Gao J, Liu J, Huang X, Zhang H, Ma A, Ye J, Zhang X, Li Y, Yang G, Yin H, Khan R, Li T, Fan S, Jiang X, Ma H, Shi Q, 2022
Biallelic HFM1 variants cause non-obstructive azoospermia with meiotic arrest in humans by impairing crossover formation to varying degrees., Xie X, Murtaza G, Li Y, Zhou J, Ye J, Khan R, Jiang L, Khan I, Zubair M, Yin H, Jiang H, Liu W, Shi B, Hou X, Gong C, Fan S, Wang Y, Jiang X, Zhang Y, Zhang H, Ma H, Shi Q, 2022
Novel frameshift mutation in STK33 is associated with asthenozoospermia and multiple morphological abnormality of the flagella., Ma H, Zhang B, Khan A, Zhao D, Ma A, Jianteng Z, Khan I, Khan K, Zhang H, Zhang Y, Xiaohua J, Dil S, Zeb A, Rahim F, Shi Q, 2021
A DNAH17 missense variant causes destabilization of doublets 4-7 in flagella and asthenozoospermia., Zhang B, Ma H, Khan T, Li T, Zhang H, Gao J, Zhou J, Ma A, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain H. M. J., Khan R, Yousaf A, Yuan L, Lu Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q, 2020
A TOP6BL mutation abolishes meiotic DNA double-strand break formation and causes human infertility., Jiao Y, Fan S, Jabeen N, Zhang H, Khan R, Murtaza G, Jiang H, Ali A, Li Y, Bao J, Zhang B, Xu J, Xu B, Hussain HMJ, Zaman Q, Khan I, Bukhari I, Iqbal F, Yousaf A, Dil S, Khan M, Ahmad N, Ma H, Jiang X, Zhang Y, Shi Q, 2020
The testis specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis., Gao Q, Khan R, Yu C, Alsheimer M, Jiang X, Ma H, Shi Q, 2020
A homozygous FANCM frameshift pathogenic variant causes male infertility., Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y, Shi Q, 2019
Zfp322a regulates mouse ES cell pluripotency and enhances reprogramming efficiency., Ma H, Ng HM, Teh X, Li H, Lee YH, Chong YM, Loh YH, Collins JJ, Feng B, Yang H, Wu Q, 2014

Spermatogenesis Maturation Molecular Mechanisms Disorders Meiosis Regulation Human Recombination Genetics Fertility

Tian Chan - Peking University

Chao-Feng Tu - Central South University

Meihong Qiu - Fudan University

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