Professor | Haibin Wang | Asia Growth Partners

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Name	Haibin Wang
Contact Information	haibin.wang@vip.163.com
Language ability	Chinese, English, Japanese
Province	Fujian

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Name

Haibin Wang

Contact Information

haibin.wang@vip.163.com

Language ability

Chinese, English, Japanese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	1992-1996: Bachelor of Science in Physiology, China Agricultural University 2000-2001: Short-term exchange student in Animal Physiology, Tokyo University of Agriculture and Technology 1996-2001: Doctor of Science in Physiology, China Agricultural University 2001-2002: Postdoctoral Research, University of Kansas Medical Center
Work Experience	2002-2008: Postdoctoral Researcher, Research Assistant Professor, Assistant Professor, Vanderbilt University Medical Center 2008-2016: Researcher, Institute of Zoology, Chinese Academy of Sciences 2016-present: Distinguished Professor, Xiamen University

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

1992-1996: Bachelor of Science in Physiology, China Agricultural University
2000-2001: Short-term exchange student in Animal Physiology, Tokyo University of Agriculture and Technology
1996-2001: Doctor of Science in Physiology, China Agricultural University
2001-2002: Postdoctoral Research, University of Kansas Medical Center

Work Experience

2002-2008: Postdoctoral Researcher, Research Assistant Professor, Assistant Professor, Vanderbilt University Medical Center
2008-2016: Researcher, Institute of Zoology, Chinese Academy of Sciences
2016-present: Distinguished Professor, Xiamen University

Areas of Focus	Molecular mechanisms of blastocyst activation Molecular regulatory network of uterine receptivity and decidualization Trophoblast cell fate determination during placental development
Publications	Bmi-1 determines uterine progesterone responsiveness essential for normal embryo implantation., Xin Q#, Kong S#, Yan J#, Qiu J, He B, Zhou C, Ni Z, Bao H, Huang L, Lu J, Xia G, Liu X, Chen Z, Wang C, Wang H., 2018 PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice., Cui T, He B, Kong S, Zhou C, Zhang H, Ni Z, Bao H, Qiu J, Xin Q, Reinberg D, Lydon JP, Lu J, Wang H., 2017 Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase., Ran H#, Kong S#, Zhang S#, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z, Wang C, Wang H., 2017 Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice., Tu Z, Wang Q, Cui T, Wang J, Ran H, Bao H, Lu J, Wang B, Lydon JP, DeMayo F, Zhang S, Kong S, Wu X, Wang H., 2016 Uterine Rbpj is required for embryo-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms., Zhang S#, Kong S#, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang HM, Wang YL, Li B, Chen Q, Duan E, Wang H., 2014 A positive feedback loop involving gcm1 and fzd5 directs chorionic branching morphogenesis in the placenta., Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang HM, Wang Y, van Es JH, Clevers H, Leone G, Cross JC, Wang H., 2013 Uterine disorders and pregnancy complications: insights from mouse models., Lim H & Wang H*., 2010 Inactivation of Nuclear Wnt-β-Catenin Signaling Limits Blastocyst Competency for Implantation., Xie H, Tranguch S, Jia X, Zhang H, Das SK, Dey SK, Kuo CJ, and Wang H., 2008 Maternal heparin-binding-EGF deficiency limits pregnancy success in mice., Xie H#, Wang H#, Tranguch S, Iwamoto R, Mekada E, DeMayo FJ, Lydon JP, Das SK and Dey SK., 2007 Roadmap to embryo implantation: Clues from mouse models., Wang H and Dey SK., 2006 Fatty acid amide hydrolase deficiency limits early pregnancy events., Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF and Dey SK., 2006 Variation in commercial rodent diets induces disparate molecular and physiological changes in the mouse uterus., Wang H#, Tranguch S#, Xie H, Hanley G, Das SK, Dey SK., 2005 Aberrant cannabinoid signaling impairs oviductal transport of embryos., Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK, DuBois RN and Dey SK., 2004 Differential G-Protein coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation., Wang H, Matsumoto H, Guo Y, Paria BC, Roberts RL, and Dey SK., 2003

Areas of Focus

Molecular mechanisms of blastocyst activation
Molecular regulatory network of uterine receptivity and decidualization
Trophoblast cell fate determination during placental development

Publications

Bmi-1 determines uterine progesterone responsiveness essential for normal embryo implantation., Xin Q#, Kong S#, Yan J#, Qiu J, He B, Zhou C, Ni Z, Bao H, Huang L, Lu J, Xia G, Liu X*, Chen Z*, Wang C*, Wang H*., 2018
PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice., Cui T, He B, Kong S, Zhou C, Zhang H, Ni Z, Bao H, Qiu J, Xin Q, Reinberg D, Lydon JP, Lu J*, Wang H*., 2017
Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase., Ran H#, Kong S#, Zhang S#, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z*, Wang C*, Wang H*., 2017
Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice., Tu Z, Wang Q, Cui T, Wang J, Ran H, Bao H, Lu J, Wang B, Lydon JP, DeMayo F, Zhang S, Kong S*, Wu X*, Wang H*., 2016
Uterine Rbpj is required for embryo-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms., Zhang S#, Kong S#, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang HM, Wang YL, Li B, Chen Q*, Duan E*, Wang H*., 2014
A positive feedback loop involving gcm1 and fzd5 directs chorionic branching morphogenesis in the placenta., Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang HM, Wang Y, van Es JH, Clevers H, Leone G, Cross JC*, Wang H*., 2013
Uterine disorders and pregnancy complications: insights from mouse models., Lim H* & Wang H*., 2010
Inactivation of Nuclear Wnt-β-Catenin Signaling Limits Blastocyst Competency for Implantation., Xie H, Tranguch S, Jia X, Zhang H, Das SK, Dey SK, Kuo CJ, and Wang H., 2008
Maternal heparin-binding-EGF deficiency limits pregnancy success in mice., Xie H#, Wang H#, Tranguch S, Iwamoto R, Mekada E, DeMayo FJ, Lydon JP, Das SK and Dey SK., 2007
Roadmap to embryo implantation: Clues from mouse models., Wang H and Dey SK., 2006
Fatty acid amide hydrolase deficiency limits early pregnancy events., Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF and Dey SK., 2006
Variation in commercial rodent diets induces disparate molecular and physiological changes in the mouse uterus., Wang H#, Tranguch S#, Xie H, Hanley G, Das SK, Dey SK., 2005
Aberrant cannabinoid signaling impairs oviductal transport of embryos., Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK, DuBois RN and Dey SK., 2004
Differential G-Protein coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation., Wang H, Matsumoto H, Guo Y, Paria BC, Roberts RL, and Dey SK., 2003

Blastocyst Activation Molecular Mechanisms Uterine Receptivity Decidualization Trophoblast Cell Fate

Guifen Liu - Tongji University

Yule Liu - Tsinghua University

Minjie Hu - Zhejiang University

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