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Xin Chen
Life Science
Xiamen University
Fujian
Language: Chinese, English
Molecular Complexes
Cellular Structures
Physiological Conditions
Pathological Conditions
Nanometer Scale
Biological System
Cell Death
Cancer
Immunity
Metabolism
Areas of Focus
- Super-resolution microscopy
- Programmed cell death
- Cancer immunity
- Metabolism homeostasis
- Organ development
Work Experience
- 2011-2018 - Postdoctoral Fellow: Xiamen University
- 2018-Present - Associate Professor: School of Life Sciences, Xiamen University
Academic Background & Achievements
- 2006 - Bachelor's Degree in Biological Sciences: Xiamen University
- 2011 - Ph.D. in Biochemistry and Molecular Biology: Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences
Publications
- Mosaic composition of RIP1-RIP3 signalling hub and its role in regulating cell death., Chen X*, Zhu R, Zhong J, Ying Y, Wang W, Cao Y, Cai H, Li X, Shuai J, Han J*, 2022
- Bifunctional Super-resolution Imaging Probe with Acidity-independent Lysosome-retention Mechanism., Xue Z, Wang S, Li J, Chen X*, Han J, Han S*, 2018
- Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis., Chen X#, He WT#, Hu L, Li J, Fang Y, Wang X, Xu X, Wang Z, Huang K, Han J*, 2016
- Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death., Chen X#, Li W#, Ren J#, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J*, 2014
- Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase., Chen X#, Ma JJ#, Tan M, Yao P, Hu QH, Eriani G, Wang ED*, 2011
- Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis., Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q, 2022
- Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2., Zhou X#, Ma F#, Xie J#, Yuan M#, Li Y#, Shaabani N#, Zhao F, Huang D, Wu NC, Lee CD, Liu H, Li J, Chen Z, Hong Y, Liu WH, Xiao N, Burton DR, Tu H, Li H, Chen X, Teijaro JR, Wilson IA*, Xiao C*, Huang Z*, 2021
- Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK., Li M#, Zhang CS#, Zong Y#, Feng JW, Ma T, Hu M, Lin Z, Li X, Xie C, Wu Y, Jiang D, Li Y, Zhang C, Tian X, Wang W, Yang Y, Chen J, Cui J, Wu YQ, Chen X, Liu QF, Wu J, Lin SY, Ye Z, Liu Y, Piao HL, Yu L, Zhou Z, Xie XS, Hardie DG, Lin SC*, 2019
- ISP1-Anchored Polarization of GCβ/CDC50A Complex Initiates Malaria Ookinete Gliding Motility., Gao H#, Yang Z#, Wang X#, Qian P, Hong R, Chen X, Su XZ, Cui H, Yuan J*, 2018
- RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis., Yang Z, Wang Y, Zhang Y, He X, Zhong CQ, Ni H, Chen X, Liang Y, Wu J, Zhao S, Zhou D, Han J*, 2018
- Plasma membrane changes during programmed cell deaths., Zhang Y, Chen X, Gueydan C, Han J*, 2018
Awards
- 2020-2023: Elected as a member of the first committee of the Cell Death Research Subcommittee of the Chinese Society for Cell Biology
