Professor | Xin Chen | Asia Growth Partners

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Name	Xin Chen
Contact Information	threegold@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Xin Chen

Contact Information

threegold@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	2006 - Bachelor's Degree in Biological Sciences: Xiamen University 2011 - Ph.D. in Biochemistry and Molecular Biology: Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences
Work Experience	2011-2018 - Postdoctoral Fellow: Xiamen University 2018-Present - Associate Professor: School of Life Sciences, Xiamen University
Awards	2020-2023: Elected as a member of the first committee of the Cell Death Research Subcommittee of the Chinese Society for Cell Biology

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

2006 - Bachelor's Degree in Biological Sciences: Xiamen University
2011 - Ph.D. in Biochemistry and Molecular Biology: Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences

Work Experience

2011-2018 - Postdoctoral Fellow: Xiamen University
2018-Present - Associate Professor: School of Life Sciences, Xiamen University

Awards

2020-2023: Elected as a member of the first committee of the Cell Death Research Subcommittee of the Chinese Society for Cell Biology

Areas of Focus	Super-resolution microscopy Programmed cell death Cancer immunity Metabolism homeostasis Organ development
Publications	Mosaic composition of RIP1-RIP3 signalling hub and its role in regulating cell death., Chen X, Zhu R, Zhong J, Ying Y, Wang W, Cao Y, Cai H, Li X, Shuai J, Han J, 2022 Bifunctional Super-resolution Imaging Probe with Acidity-independent Lysosome-retention Mechanism., Xue Z, Wang S, Li J, Chen X, Han J, Han S, 2018 Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis., Chen X#, He WT#, Hu L, Li J, Fang Y, Wang X, Xu X, Wang Z, Huang K, Han J, 2016 Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death., Chen X#, Li W#, Ren J#, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J, 2014 Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase., Chen X#, Ma JJ#, Tan M, Yao P, Hu QH, Eriani G, Wang ED, 2011 Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis., Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q, 2022 Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2., Zhou X#, Ma F#, Xie J#, Yuan M#, Li Y#, Shaabani N#, Zhao F, Huang D, Wu NC, Lee CD, Liu H, Li J, Chen Z, Hong Y, Liu WH, Xiao N, Burton DR, Tu H, Li H, Chen X, Teijaro JR, Wilson IA, Xiao C, Huang Z, 2021 Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK., Li M#, Zhang CS#, Zong Y#, Feng JW, Ma T, Hu M, Lin Z, Li X, Xie C, Wu Y, Jiang D, Li Y, Zhang C, Tian X, Wang W, Yang Y, Chen J, Cui J, Wu YQ, Chen X, Liu QF, Wu J, Lin SY, Ye Z, Liu Y, Piao HL, Yu L, Zhou Z, Xie XS, Hardie DG, Lin SC, 2019 ISP1-Anchored Polarization of GCβ/CDC50A Complex Initiates Malaria Ookinete Gliding Motility., Gao H#, Yang Z#, Wang X#, Qian P, Hong R, Chen X, Su XZ, Cui H, Yuan J, 2018 RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis., Yang Z, Wang Y, Zhang Y, He X, Zhong CQ, Ni H, Chen X, Liang Y, Wu J, Zhao S, Zhou D, Han J, 2018 Plasma membrane changes during programmed cell deaths., Zhang Y, Chen X, Gueydan C, Han J, 2018

Areas of Focus

Super-resolution microscopy
Programmed cell death
Cancer immunity
Metabolism homeostasis
Organ development

Publications

Mosaic composition of RIP1-RIP3 signalling hub and its role in regulating cell death., Chen X*, Zhu R, Zhong J, Ying Y, Wang W, Cao Y, Cai H, Li X, Shuai J, Han J*, 2022
Bifunctional Super-resolution Imaging Probe with Acidity-independent Lysosome-retention Mechanism., Xue Z, Wang S, Li J, Chen X*, Han J, Han S*, 2018
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis., Chen X#, He WT#, Hu L, Li J, Fang Y, Wang X, Xu X, Wang Z, Huang K, Han J*, 2016
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death., Chen X#, Li W#, Ren J#, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J*, 2014
Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase., Chen X#, Ma JJ#, Tan M, Yao P, Hu QH, Eriani G, Wang ED*, 2011
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis., Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q, 2022
Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2., Zhou X#, Ma F#, Xie J#, Yuan M#, Li Y#, Shaabani N#, Zhao F, Huang D, Wu NC, Lee CD, Liu H, Li J, Chen Z, Hong Y, Liu WH, Xiao N, Burton DR, Tu H, Li H, Chen X, Teijaro JR, Wilson IA*, Xiao C*, Huang Z*, 2021
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK., Li M#, Zhang CS#, Zong Y#, Feng JW, Ma T, Hu M, Lin Z, Li X, Xie C, Wu Y, Jiang D, Li Y, Zhang C, Tian X, Wang W, Yang Y, Chen J, Cui J, Wu YQ, Chen X, Liu QF, Wu J, Lin SY, Ye Z, Liu Y, Piao HL, Yu L, Zhou Z, Xie XS, Hardie DG, Lin SC*, 2019
ISP1-Anchored Polarization of GCβ/CDC50A Complex Initiates Malaria Ookinete Gliding Motility., Gao H#, Yang Z#, Wang X#, Qian P, Hong R, Chen X, Su XZ, Cui H, Yuan J*, 2018
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis., Yang Z, Wang Y, Zhang Y, He X, Zhong CQ, Ni H, Chen X, Liang Y, Wu J, Zhao S, Zhou D, Han J*, 2018
Plasma membrane changes during programmed cell deaths., Zhang Y, Chen X, Gueydan C, Han J*, 2018

Molecular Complexes Cellular Structures Physiological Conditions Pathological Conditions Nanometer Scale Biological System Cell Death Cancer Immunity Metabolism

Changdong Lin - Tongji University

Zhongliang Ma - Shanghai University

Chenhui Wang - Huazhong University of Science and Technology

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