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Yong Yu
Life Science
Xiamen University
Fujian
Language: English, Chinese
Lipid Metabolism
Obesity
Aging
Raman Scattering
Microscopy
C. Elegans
Chemical Imaging
Lipid Quantification
Metabolic Regulation
Drug Discovery
Areas of Focus
- Lipid Metabolism
- Aging and Obesity
Work Experience
- 2007-2008 - University of Michigan - Visiting Scholar
- 2011-2019 - Baylor College of Medicine - Postdoctoral Fellow
- 2019-Present - Xiamen University, School of Life Sciences - Associate Professor/Principal Investigator
Academic Background & Achievements
- 2006 - Bachelor's Degree in Biotechnology: Xiamen University
- 2011 - Ph.D. in Cell Biology: Institute of Biophysics, Chinese Academy of Sciences
Publications
- Temperature-dependent lifespan extension is achieved in miR-80-deleted Caenorhabditis elegans by NLP-45 to modulate endoplasmic reticulum unfolded protein responses., C Zhao, J Luo*, Y Zhang, Y Yu*, 2024
- Anemarrhena asphodeloides Bunge total saponins lower lipid via modulating MAOA activity to enhance defense mechanisms in mice and C. elegans., K Shi, B Jing, Y Feng*, Y Yu*, 2024
- A fluorescence lifetime-based novel method for accurate lipid quantification of BODIPY vital-stained C. elegans., C Xu, J Luo, Y Yu*, 2024
- Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity., Y Yu#,*, SM Gao#, Y Guan#, PW Hu, Q Zhang, J Liu, B Jing, Q Zhao, DM Sabatini, M Abu-Remaileh, SY Jung, MC Wang*, 2024
- High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation., Y Yu, AS Mutlu, H Liu, MC Wang*, 2017
- In vivo metabolic fingerprinting of neutral lipids with hyperspectral stimulated Raman scattering microscopy., D Fu#,Y Yu#, A Folick, et al., 2014
- Shedding new light on lipid functions with CARS and SRS microscopy., Y Yu, PV. Ramachandran, and MC Wang*, 2014
- A Systematic RNAi Screen Reveals a Novel Role of a Spindle Assembly Checkpoint Protein BuGZ in Synaptic Transmission in C. elegans., M Han#, W Zou#, H Chang#,Y Yu#, et al., 2017
- HID-1 is a novel player in the regulation of neuropeptide sorting., Y Yu#, L Wang#, Y Jiu#, et al., 2011
- Vibrational imaging of newly synthesized proteins in live cells by stimulated Raman scattering microscopy., L Wei, Y Yu, Y Shen, et al., 2013
- Quantitative Imaging of Glutathione in Live Cells Using a Reversible Reaction-Based Ratiometric Fluorescent Probe., X Jiang, Y Yu, J Chen, M Zhao, et al., 2015
- Lysosomal Signaling Molecules Regulate Longevity in Caenorhabditis elegans., A Folick, HD Oakley, Y Yu, et al., 2015
- Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering., L Wei, F Hu, Y Shen, Z Chen, Y Yu, et al., 2014
- The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A., L Huo#, Y Yue#, J Ren, J Yu, J Liu, Y Yu, et al., 2012
- The CC1-FHA dimer is essential for KIF1A-mediated axonal transport of synaptic vesicles in C. elegans., Y Yue#, Y Sheng#, H Zhang#, Y Yu, et al., 2013
- C. elegans phototransduction requires a G protein-dependent cGMP pathway and a taste receptor homolog., J Liu#, A Ward#, J Gao, Y Dong, N Nishio, H Inada, L Kang, Y Yu, et al., 2010
- HID-1 is a peripheral membrane protein primarily associated with the medial- and trans-Golgi apparatus., L Wang#, Y Zhan#, E Song#, Y Yu, et al., 2011
Awards
- 2020 - Fujian Province High-Level Talent (Overseas Category C)
- 2019 - Xiamen University Nanqiang Young Top Talent (Category B)
- 2019 - First Prize Best Poster Award in Nature Conference on Cellular Metabolism
- 2019 - First Prize Best Poster Award in 5th LipidALL International Lipid Symposium
