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Bo Wang
Life Science
Xiamen University
Fujian
Language: English, Chinese
Rna Metabolism
Cellular Mechanisms
Molecular Mechanisms
Degenerative Diseases
Als
Ftd
Ibm
Autophagy
Neurodegeneration
Pathogenesis
Areas of Focus
- Cellular and molecular mechanisms of RNA metabolism
- Role of autophagy in neurodegeneration
Work Experience
- 2017-2019 - St. Jude Children's Research Hospital - Postdoctoral Researcher
- 2020-Present - Xiamen University, School of Life Sciences - Professor
Academic Background & Achievements
- 2011 - Bachelor's Degree in Biotechnology: Huazhong University of Science and Technology
- 2016 - PhD in Neuroscience: University of Tennessee Health Science Center
Publications
- ULK/Atg1: phasing in and out of autophagy, Wang, B., Pareek, G., and Kundu, M., 2024
- Paxillin Phase Separation Promotes Focal Adhesion Assembly and Integrin Signaling, Liang, P., Wu, Y., Zheng, S., Zhang, J., Yang, S., Wang, J., Ma, S., Zhang, M., Gu, Z., Liu, Q., Jiang, W., Xing, Q., and Wang, B., 2024
- An autophagy-independent role of ULK1/ULK2 in mechanotransduction and breast cancer cell migration, Liang, P., and Wang, B., 2024
- SRRM2 Phase Separation Drives Assembly of Nuclear Speckle Subcompartments, Zhang, M., Gu, Z., Ma, S., Yang, S., Guo, J., Shu, L., Ge, Y., Chen, Z., and Wang, B., 2024
- An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration, Liang, P., Zhang, J., Wu, W., Zheng, S., Xu, Z., Yang, S., Wang, J., Ma, S., Xiao, L., Hu, T., Jiang, W., Huang, C., Xing, Q., Kundu, M., and Wang, B., 2023
- Emerging Roles of Ubiquitination in Biomolecular Condensates, Liang, P., Zhang, J., and Wang, B., 2023
- ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis, Li, D., Vogel, P., Li, XJ., Wang, B. & Kundu, M., 2021
- ER-to-Golgi trafficking and its implication in neurological diseases, Wang, B., Stanford, K. & Kundu, M., 2020
- ULK1/2 regulate stress granule disassembly through phosphorylation and activation of VCP, Wang, B., Maxwell, B., Joo, J.H., Gwon, Y., Messing, J., Mishra, A., Shaw, T., Ward, A., Quan, H., Sakurada, S.M., et al., 2019
- The COPII cargo adapter SEC24C is essential for neuronal homeostasis, Wang, B., Joo, JH., Mount, R., Teubner, BJW., Krenzer, A., Ward, AL., Ichhaporia, VP., Elizabeth AJ., Khoriaty, R., Peters ST., et al., 2018
- The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway, Wang, B., Iyengar, R., Li-Harms, X., Joo, J.H., Wright, C., Lavado, A., Yang, M., Guan, JL., Green, DR., Cao, X., and Kundu, M., 2017
- Canonical and noncanonical functions of ULK/Atg1, Wang, B. & Kundu, M., 2017
- The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis, Joo, J.H., Wang, B., Frankel, E., Ge, L., Xu, L., Iyengar, R., Li-Harms, X., Wright, C., Shaw, T.I., Lindsten, T., et al., 2016
- VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations, Kim, N.C., Tresse, E., Kolaitis, R.M., Molliex, A., Thomas, R.E., Alami, N.H., Wang, B., Joshi, A., Smith, R.B., Ritson, G.P., et al., 2013
- Poly(Lactic Acid)-Based Biomaterials: Synthesis, Modification and Applications, Xiao, L., Wang, B., Yang, G., and Gauthier, G., 2012
Awards
- Fujian Natural Science Foundation, General Project, 2023J01024, 2023-08-01 to 2026-08-01, 60,000 RMB, Principal Investigator
- National Natural Science Foundation of China, General Project, 32071235, 2021-01-01 to 2024-12-31, 570,000 RMB, Principal Investigator
- Guangdong Regional Joint Fund Youth Fund Project, 2020A1515111186, 2020-10 to 2023-9, 100,000 RMB, Principal Investigator
