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Ximin Chi
Life Science
Xiamen University
Fujian
Language: Chinese, English
Membrane Proteins
Protein Complexes
Cryo-Electron Microscopy
Structural Analysis
Functional Mechanism
Neurological Diseases
Regulatory Mechanisms
Cellular Stress Biology
Drug Development
Biochemistry
Areas of Focus
- Structural analysis and functional mechanism research of membrane proteins and protein complexes by cryo-electron microscopy
Work Experience
- 2019-2020 - Westlake University - Research Assistant
- 2021-2023 - Westlake University - Postdoctoral Fellow
- 2023-Present - Xiamen University - Associate Professor
Academic Background & Achievements
- 2010-2014 B.S.: Xiamen University, Biological Science
- 2014-2019 Ph.D.: Tsinghua University, Biology
Publications
- Modulation of cardiac ryanodine receptor 2 by calmodulin, Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N, 2019
- Cryo-EM structures of the full-length human KCC2 and KCC3 cation-chloride cotransporters, Chi X, Li X, Chen Y, Zhang Y, Su Q, Zhou Q, 2021
- Structural mechanism of phospholipids translocation by MlaFEDB complex, Chi X, Fan Q, Zhang Y, Liang K, Wan L, Zhou Q, Li Y, 2020
- Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators, Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N, 2019
- Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin, Gong D, Chi X, Ren K, Huang G, Zhou G, Yan N, Lei J, Zhou Q, 2018
- Rational exploration of fold atlas for human solute carrier proteins, Xie T, Chi X, Huang B, Ye F, Zhou Q, Huang J, 2022
- Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence, Chi X, Jin X, Chen Y, Lu X, Tu X, Li X, Zhang Y, Lei J, Huang J, Huang Z, Zhou Q, Pan X, 2020
- Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against sars-cov-2 omicron variants, Chi X, Xia L, Zhang G, Chi X, Huang B, Zhang Y, Chen Z, Han J, Wu L, Li Z, Sun H, Huang P, Yu C, Chen W, Zhou Q, 2023
