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Mengqi Li
Life Science
Xiamen University
Fujian
Language: Chinese, English
Metabolism
Cellular Organelles
Molecular Mechanisms
Physiological Functions
Coordination
Regulation
Biochemistry
Molecular Biology
Cell Biology
Life Sciences
Areas of Focus
- Metabolic Biology
Work Experience
- 2019-2022 - Xiamen University - Postdoctoral Fellow
- 2023 - Xiamen University - Associate Professor
Academic Background & Achievements
- 2009-2013 B.S.: Xiamen University, Biological Sciences
- 2013-2019 Ph.D.: Xiamen University, Biochemistry and Molecular Biology
- Fujian Province Excellent Doctoral Dissertation, 2019
Publications
- Identification of serum metabolites enhancing inflammatory responses in COVID-19., Zhang CS, Zhang B, Li M, Wei X, Gong K, Li Z, Yao X, Wu J, Zhang C, Zhu M, Zhang L, Sun X, Zhan YH, Jiang Z, Zhao W, Zhong W, Zhuang X, Zhou D, Piao HL, Lin SC, Wang Z., 2022
- The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK., Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC., 2022
- Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1., Li M, Zhang CS, Feng JW, Wei X, Zhang C, Xie C, Wu Y, Hawley SA, Atrih A, Lamont DJ, Wang Z, Piao HL, Hardie DG, Lin SC., 2021
- Transient Receptor Potential V channels are essential for Glucose Sensing by Aldolase and AMPK., Li M, Zhang CS, Zong Y, Feng JW, et al., Lin SC., 2019
- Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress., Zong Y, Zhang CS, Li M, Wang W, Wang ZH, Simon A. H, Ma T, Feng JW, Tian X, Qi Q, Wu YQ, Zhang CX, Ye ZY, Lin SY, Piao HL, D. G Hardie, Lin SC., 2019
- Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK., Zhang CS, Hawley SA, Zong Y, Li M, Wang ZC, Gray A, Ma T, Cui JW, Feng JW, Zhu MJ, Wu YQ, Li TY, Ye Z, Lin SY, Yin HY, Piao HL, Hardie DG, Lin SC., 2016
- Metformin activates AMPK through the lysosomal pathway., Zhang CS, Li M, Ma T, Zong Y, Cui J, Feng JW, Wu, YQ, Lin SY, and Lin SC., 2016
- RHOBTB3 promotes proteasomal degradation of HIF1alpha through facilitating hydroxylation and suppresses the Warburg effect., Zhang CS, Liu Q, Li M, Lin SY, Peng YY, Wu D, Li TY, Fu Q, Jia WP, Wang XJ, Ma T, Zong Y, Cui JW, Pu CF, Lian GL, Guo GL, Ye ZY, Lin SC., 2015
- The Lysosomal v-ATPase-Ragulator Complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism., Zhang CS, Jiang B, Li M, Zhu MJ, Peng YY, Zhang YL, Wu YQ, Li TY, Liang Y, Lu ZL, Lian GL, Liu Q, Guo HL, Yin ZY, Ye ZY, Han J, Wu JW, Yin HY, Lin SY, Lin SC., 2014
Awards
- Xiamen University Nanqiang Young Top Talent (Category B), 2022
- Top Ten Advances in Life Sciences in China, 2017
- National Natural Science Foundation of China General Grant, 2020
