Upload Avatar (500 x 500)
Pingli Mo
mop@xmu.edu.cn
English, Chinese
Fujian
Xiamen University
Life Sciences
  • 1996-2000 B.S. in Biology: Guangxi University
  • 2000-2003 M.S. in Biology: Guangxi University
  • 2003-2006 Ph.D. in Molecular Biology: Xiamen University
  • 2007 Chinese Postdoctoral Fellowship, First Prize
  • 2000 Outstanding Graduate, Guangxi University
  • 1999 He Kang Scholarship
  • 2011-present - Xiamen University - Associate Professor
  • 2008-2010 - Albany Medical College - Postdoctoral Research Associate
  • 2006-2007 - Shanghai Institute of Biochemistry and Cell Biology - Postdoctoral Research Associate
  • 2007: Chinese Postdoctoral Fellowship, First Prize
  • 2000: Outstanding Graduate, Guangxi University
  • 1999: He Kang Scholarship
Cancer signaling pathways
Tumor development and progression
  • Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling., Guo P*, Chen Q*, Peng K*, Xie J, Liu J, Ren W, Tong Z, Li M, Xu J, Zhang Y#, Yu C#, Mo P#., 2022
  • Histone Demethylase JMJD2D: A Novel Player in Colorectal and Hepatocellular Cancers., Chen Q, Peng K, Mo P#, Yu C#., 2022
  • Traditional Chinese Medicine Pien-Tze-Huang Inhibits Colorectal Cancer Growth and Immune Evasion by Reducing β-catenin Transcriptional Activity and PD-L1 Expression., Chen Q *, Hong Y*, Weng S, Guo P, Li B, Zhang Y, Yu C#, Wang S# , Mo P#., 2022
  • Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression., Peng K*, Zhuo M*, Li M, Chen Q, Mo P#, Yu C#., 2020
  • Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling., Zhuo M*, Chen W*, Shang S, Guo P, Peng K, Li M, Mo P, Zhang Y, Qiu X, Li W, Yu C., 2020
  • Steroid receptor coactivator 3 inhibits hepatitis B virus gene expression through activating Akt signaling to prevent HNF4α nuclear translocation., Li M, Wang Y, Xia X, Mo P, Xu J, Yu C, Li W., 2019
  • Histone demethylase JMJD2D promotes the self-renewal of liver cancer stem-like cells by enhancing EpCAM and Sox9 expression., Deng Y*, Li M*, Zhuo M, Guo P, Chen Q, Mo P, Li W, Yu C., 2020
  • Demethylase-independent function of JMJD2D as a novel antagonist of p53 to promote Liver Cancer initiation and progression., Li M*, Deng Y*, Zhuo M, Zhou H, Kong X, Xia X, Su Z, Chen Q, Guo P, Mo P, Yu C, Li W., 2020
  • Steroid receptor coactivator 3 inhibits hepatitis B virus gene expression through activating Akt signaling to prevent HNF4α nuclear translocation., Li M, Wang Y, Xia X, Mo P, Xu J, Yu C, Li W., 2019
  • Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice., Peng K, Kou L, Yu L, Bai C, Li M, Mo P, Li W, Yu C., 2019
  • Roles of Steroid Receptor Coactivator 3 in Host Defense Against Bacterial Pathogens., Chen W*, Mo P*, Yu C., 2018
  • Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling., Peng K*, Su G*, Ji J, Yang X, Miao M, Mo P, Li M, Xu J, Li W, Yu C., 2018
  • The store-operated calcium channels in cancer metastasis: from cell migration, invasion to metastatic colonization., Mo P, Yang S., 2018
  • Steroid Receptor Coactivator 3 Contributes to Host Defense against Enteric Bacteria by Recruiting Neutrophils via Upregulation of CXCL2 Expression., Chen W, Lu X, Chen Y, Li M, Mo P, Tong Z, Wang W, Wan W, Su G, Xu J, Yu C., 2017
  • Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression., Majaz S*, Tong Z*, Peng K, Wang W, Ren W, Li M, Liu K, Mo P, Li W, Yu C., 2016
  • Downregulation of amplified in breast cancer 1 contributes to the anti-tumor effects of sorafenib on human hepatocellular carcinoma., Li M*, Wang W*, Dan Y, Tong Z, Chen W, Qin L, Liu K, Li W, Mo P#, Yu C#., 2016
  • Steroid Receptor Coactivator 1 Promotes Human Hepatocellular Carcinoma Progression by Enhancing Wnt/β-Catenin Signaling., Tong Z*, Li M*, Wang W, Mo P, Yu L, Liu K, Ren W, Li W, Zhang H, Xu J, Yu C., 2015
  • Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling., Mo P*, Zhou Q*, Guan L*, Wang Y, Wang W, Miao M, Tong Z, Li M, Majaz S, Liu Y, Su G, Xu J, Yu C., 2015
  • Deficiency in steroid receptor coactivator 3 enhances cytokine production in IgE-stimulated mast cells and passive systemic anaphylaxis in mice., Xia X, Wan W, Chen Q, Liu K, Majaz S, Mo P, Xu J, Yu C., 2014
  • Mycoepoxydiene inhibits antigen-stimulated activation of mast cells and suppresses IgE-mediated anaphylaxis in mice., Xia XC, Chen Q, Liu K, Mo PL, Zhu JW, Zhuang MQ, Shen YM, Yu CD., 2013
  • Mycoepoxydiene suppresses RANKL-induced osteoclast differentiation and reduces ovariectomy-induced bone loss in mice., Zhu J, Chen Q, Xia X, Mo P, Shen Y, Yu C., 2013
  • MDM2 mediates ubiquitination and degradation of activating transcription factor 3., Mo P, Wang H, Lu H, Boyd D, Yan C., 2010
  • Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6., Wang H*, Mo P*, Ren S, Yan C., 2010
  • Identification of two phosphatidylinositol / phosphatidylcholine transfer proteins that are predominately transcribed in the flowers of Arabidopsis thaliana., Mo P, Zhu Y, Liu X, Wang D., 2007
Cancer Signaling Wnt Notch P53 Dna Repair Pi3K Tumor Pathways Therapies

Contact us

Let's talk!
* Required
* Required
* Required
* Invalid email address
By submitting this form, you agree that IoT ONE may contact you with insights and marketing messaging.
No thanks, I don't want to receive any marketing emails from IoT ONE.
Submit

Thank you for your message!
We will contact you soon.