2006-2014 - Assistant Professor, School of Life Sciences, Xiamen University
2014-2020 - Associate Professor, School of Life Sciences, Xiamen University
2020-Present - Professor, School of Life Sciences, Xiamen University
Research
Molecular Virology Molecular Vaccinology Animal Model Research
Cryo-EM Structures Reveal the Molecular Basis of Receptor-Initiated Coxsackievirus Uncoating, Xu L, Zheng Q, Zhu R, Yin Z, Yu H, Lin Y, Wu Y, He M, Huang Y, Jiang Y, Sun H, Zha Z, Yang H, Huang Q, Zhang D, Chen Z, Ye X, Han J, Yang L, Liu C, Que Y, Fang M, Gu Y, Zhang J, Luo W, Zhou ZH, Li S, Cheng T, Xia N, 2021
Development of a skin- and neuro-attenuated live vaccine for varicella, Wang W, Pan D, Fu W, Ye X, Han J, Yang L, Jia J, Liu J, Zhu R, Zhang Y, Liu C, Ye J, Selariu A, Que Y, Zhao Q, Wu T, Li Y, Zhang J, Cheng T, Zhu H, Xia N, 2022
Cross-species tropism and antigenic landscapes of circulating SARS-CoV-2 variants, Zhang Y, Wei M, Wu Y, Wang J, Hong Y, Huang Y, Yuan L, Ma J, Kai Wang, Wang S, Shi Y, Wang Z, Guo H, Xiao J, Yang C, Ye J, Chen J, Liu Y, Fu B, Lan M, Gong P, Huang Z, Su Y, Chen Y, Zhang T, Zhang J, Zhu H, Yu H, Yuan Q, Cheng T, Guan Y, Xia N, 2022
Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids, Wang W, Zheng Q, Pan D, Yu H, Fu W, Liu J, He M, Zhu R, Cai Y, Huang Y, Zha Z, Chen Z, Ye X, Han J, Que Y, Wu T, Zhang J, Li S, Zhu H, Zhou ZH, Cheng T, Xia N, 2020
Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16, He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N, 2020
Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization, Zheng Q, Zhu R, Xu L, He M, Yan X, Liu D, Yin Z, Wu Y, Li Y, Yang L, Hou W, Li S, Li Z, Chen Z, Li Z, Yu H, Gu Y, Zhang J, Baker TS, Zhou ZH, Graham BS, Cheng T, Li S, Xia N, 2019
Agonist c-Met Monoclonal Antibody Augments the Proliferation of hiPSC-derived Hepatocyte-Like Cells and Improves Cell Transplantation Therapy for Liver Failure in Mice, Yuan L, Zhang Y, Liu X, Chen Y, Zhang L, Cao J, Li X, Wang M, Wu K, Zhang J, Liu G, Tang Q, Yuan Q, Cheng T, Xia N, 2019
Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10, Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Hong Zhou Z, Cheng T, Xia N, 2018
HBV infection-induced liver cirrhosis development in dual-humanized mice with human bone mesenchymal stem cell transplantation, Yuan L, Jiang J, Liu X, Zhang Y, Zhang L, Xin J, Wu K, Li X, Cao J, Guo X, Shi D, Li J, Jiang L, Sun S, Wang T, Hou W, Zhang T, Zhu H, Zhang J, Yuan Q, Cheng T, Li J, Xia N, 2019
Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody, Xu L, Zheng Q, Li S, He M, Wu Y, Li Y, Zhu R, Yu H, Hong Q, Jiang J, Li Z, Li S, Zhao H, Yang L, Hou W, Wang W, Ye X, Zhang J, Baker TS, Cheng T, Zhou ZH, Yan X, Xia N, 2017
Optimized HepaRG is a suitable cell source to generate human liver chimeric mouse model for chronic hepatitis B virus infection, Yuan L, Liu X, Zhang L, Zhang Y, Chen Y, Li X, Wu K, Cao J, Hou W, Que Y, Zhang J, Zhu H, Yuan Q, Tang Q, Cheng T, Xia N, 2018
A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cell for the Chronic Hepatitis B Virus Infection, Yuan L, Liu X, Zhang L, Li X, Zhang Y, Wu K, Cao J, Hou W, Zhang J, Zhu H, Yuan Q, Tang Q, Cheng T, Xia N, 2018
Zika Virus Fatally Infects Wild Type Neonatal Mice and Replicates in Central Nervous System, Li S, Armstrong N, Zhao H, Hou W, Liu J, Chen C, Wan J, Wang W, Zhong C, Liu C, Zhu H, Xia N, Cheng T, Tang Q, 2018
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization, Wang W, Fu W, Pan D, Cai L, Ye J, Liu J, Liu C, Que Y, Xia N, Zhu H, Cheng T, 2017
A neonatal mouse model of coxsackievirus A10 infection for anti-viral evaluation, Li S, Zhao H, Yang L, Hou W, Xu L, Wu Y, Wang W, Chen C, Wan J, Ye X, Liang Z, Mao Q, Cheng T, Xia N, 2017
A novel combined vaccine based on monochimeric VLP co-displaying multiple conserved epitopes against Enterovirus 71 and Varicella-Zoster Virus, Wu Y, Zhu R, Xu L, Li Y, Li S, Yu H, Li S, Zhu H, Cheng T, Xia N, 2017
Modulation of host CD59 expression by varicella-zoster virus in human xenografts in vivo, Wang W, Wang X, Yang L, Fu W, Pan D, Liu J, Ye J, Zhao Q, Zhu H, Cheng T, Xia N, 2016
A highly conserved epitope-vaccine candidate against varicella-zoster virus induces neutralizing antibodies in mice, Zhu R, Liu J, Chen C, Ye X, Xu L, Wang W, Zhao Q, Zhu H, Cheng T, Xia N, 2016
A monoclonal antibody-based VZV Glycoprotein E Quantitative Assay and Its Application on Antigen Quantitation in VZV Vaccine, Liu J, Zhu R, Ye X, Yang L, Wang Y, Huang Y, Wu J, Wang W, Ye J, Li Y, Zhao Q, Zhu H, Cheng T, Xia N, 2015
Protection against lethal Enterovirus 71 challenge in mice by a recombinant vaccine candidate containing a broadly cross-neutralizing epitope within the VP2 EF loop, Xu L, He D, Li Z, Zheng J, Yang L, Yu M, Yu H, Chen Y, Que Y, Shih JW, Liu G, Zhang J, Zhao Q, Cheng T, Xia N, 2014
