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Wen Liu
English, Chinese
Fujian
Xiamen University
Life Sciences
  • 2001 - Bachelor's degree in Biology: Xiamen University
  • 2011 - PhD in Biology: University of California, San Diego
  • 2002 to 2005 - Sanford-Burnham Medical Research Institute
  • 2011 to 2013 - University of California, San Diego School of Medicine
  • Current - Minjiang Scholar Distinguished Professor, Xiamen University
Gene transcription and splicing abnormalities in cancer and major human diseases
  • JMJD6 licenses estrogen receptor a-dependent enhancer and coding gene activation by modulating the recruitment of the CARM1/MED12 co-activator complex., Gao WW, Xiao RQ, Zhang WJ, Hu YR, Peng BL, Li WJ, He YH, Shen HF, Ding JC, Huang QX, Ye TY, Li Y, Liu ZY, Ding R, Rosenfeld MG, Liu W., 2018
  • Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation., Wu XN, Shi TT, He YH, Wang FF, Sang R, Ding JC, Zhang WJ, Shu XY, Shen HF, Yi J, Gao X, Liu W., 2017
  • JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner., Yi J, Shen HF, Qiu JS, Huang MF, Zhang WJ, Ding JC, Zhu XY, Zhou Y, Fu XD, Liu W., 2016
  • Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation., Zhang WJ, Wu XN, Shi TT, Xu HT, Yi J, Shen HF, Huang MF, Su XY, Wang FF, Peng BL, Xiao RQ, Gao WW, Ding JC, Liu W., 2016
  • Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation., Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W., 2015
  • Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause Release., Liu W, Ma Q, Wong K, Li W, Ohgi K, Zhang J, Aggarwal AK, Rosenfeld MG., 2013
  • PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression., Liu W, Tanasa B, Tyurina O.V., Zhou T.Y., Gassmann R, Liu W.T., Ohgi K.A., Benner C, Garcia-Bassets I, Aggarwal A.K., Desai A, Dorrestein P.C., Glass C.K., Rosenfeld M.G., 2010
  • NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling., Zhou Hu, Liu W, Su Y, Wei Z, Liu J, Kolluri S.K., Wu H, Cao Y, Chen J, Wu Y, Yan T, Cao X, Gao W, Molotkov A, Jiang F, Li W.G., Lin B, Zhang H.P., Yu J, Luo S.P., Zeng J.Z., Duester G, Huang P.Q., Zhang X.K., 2010
Gene Transcription Splicing Cancer Human Diseases Nuclear Receptors Transcription Factors Epigenetic Regulators Non-Coding Rna Drug Targets Molecular Mechanisms

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