Professor | Jialiang Huang | Asia Growth Partners

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Name	Jialiang Huang
Contact Information	jhuang@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Jialiang Huang

Contact Information

jhuang@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	2005 - B.S. in Bioengineering: Fuzhou University 2008 - M.S. in Computer Software and Theory: Fuzhou University 2012 - Ph.D. in Bioinformatics: Chinese Academy of Science
Work Experience	2011-2013 - Scientist at GlaxoSmithKline (China) R&D Co., Ltd., Shanghai 2013-2018 - Postdoc at Dana-Farber Cancer Institute/Boston Children's Hospital, Harvard Medical School 2018-Present - Principal Investigator at School of Life Sciences, Xiamen University

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

2005 - B.S. in Bioengineering: Fuzhou University
2008 - M.S. in Computer Software and Theory: Fuzhou University
2012 - Ph.D. in Bioinformatics: Chinese Academy of Science

Work Experience

2011-2013 - Scientist at GlaxoSmithKline (China) R&D Co., Ltd., Shanghai
2013-2018 - Postdoc at Dana-Farber Cancer Institute/Boston Children's Hospital, Harvard Medical School
2018-Present - Principal Investigator at School of Life Sciences, Xiamen University

Areas of Focus	Epigenetic regulation mechanisms of mammalian development and cancer
Publications	Single-cell chromatin accessibility reveals enhancer networks driving gene expression during spinal cord development., M. Shu, D. Hong, H. Lin, J. Zhang, Z. Luo, Y. Du, Z. Sun, M. Yin, Y. Yin, L. Liu, S. Bao, Z. Liu, F. Lu, J. Huang, J. Dai, 2022 Complexity of enhancer networks predicts cell identity and disease genes revealed by single-cell multi-omics analysis., D. Hong, H. Lin, L. Liu, M. Shu, J. Dai, F. Lu, M. Tong, J. Huang, 2022 Single-cell transcriptional regulation and genetic evolution of neuroendocrine prostate cancer., Z. Wang, T. Wang, D. Hong, B. Dong, Y. Wang, H. Huang, W. Zhang, B. Lian, B. Ji, H. Shi, M. Qu, X. Gao, D. Li, C. Collins, G. Wei, C. Xu, H. J. Lee, J. Huang, J. Li, 2022 Mapping the evolving landscape of super-enhancers during cell differentiation., Y. Kai, B. E. Li, M. Zhu, G. Y. Li, F. Chen, Y. Han, H. J. Cha, S. H. Orkin, W. Cai, J. Huang, G.-C. Yuan, 2021 Enhancer-dependence of cell-type-specific gene expression increases with developmental age., W. Cai, J. Huang, Q. Zhu, B. Li, D. Seruggia, P. Zhou, M. Nguyen, Y. Fujiwara, H. Xie, Z. Yang, D. Hong, P. Ren, J. Xu, W. Pu, G.-C. Yuan, S. H. Orkin, 2020 Dissecting super-enhancer hierarchy based on chromatin interactions., J. Huang, K. Li, W. Cai, X. Liu, Y. Zhang, S. H. Orkin, J. Xu, G.-C. Yuan, 2018 Multi-scale chromatin state annotation using a hierarchical hidden Markov model., E. Marco, W. Meuleman, J. Huang, K. Glass, L. Pinello, J. Wang, M. Kellis, G.-C. Yuan, 2017 Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis., J. Huang, X. Liu, D. Li, Z. Shao, H. Cao, Y. Zhang, E. Trompouki, T. V. Bowman, L. I. Zon, G.-C. Yuan, S. H. Orkin, J. Xu, 2016 Predicting chromatin organization using histone marks., J. Huang, E. Marco, L. Pinello, G.-C. Yuan, 2015 Systematic prediction of pharmacodynamic drug-drug interactions through protein-protein-interaction network., J. Huang, C. Niu, C. D. Green, L. Yang, H. Mei, J.-D. J. Han, 2013 eResponseNet: a package prioritizing candidate disease genes through cellular pathways., J. Huang, Y. Liu, W. Zhang, H. Yu, J.-D. J. Han, 2011

Areas of Focus

Epigenetic regulation mechanisms of mammalian development and cancer

Publications

Single-cell chromatin accessibility reveals enhancer networks driving gene expression during spinal cord development., M. Shu, D. Hong, H. Lin, J. Zhang, Z. Luo, Y. Du, Z. Sun, M. Yin, Y. Yin, L. Liu, S. Bao, Z. Liu, F. Lu, J. Huang, J. Dai, 2022
Complexity of enhancer networks predicts cell identity and disease genes revealed by single-cell multi-omics analysis., D. Hong, H. Lin, L. Liu, M. Shu, J. Dai, F. Lu, M. Tong, J. Huang, 2022
Single-cell transcriptional regulation and genetic evolution of neuroendocrine prostate cancer., Z. Wang, T. Wang, D. Hong, B. Dong, Y. Wang, H. Huang, W. Zhang, B. Lian, B. Ji, H. Shi, M. Qu, X. Gao, D. Li, C. Collins, G. Wei, C. Xu, H. J. Lee, J. Huang, J. Li, 2022
Mapping the evolving landscape of super-enhancers during cell differentiation., Y. Kai, B. E. Li, M. Zhu, G. Y. Li, F. Chen, Y. Han, H. J. Cha, S. H. Orkin, W. Cai, J. Huang, G.-C. Yuan, 2021
Enhancer-dependence of cell-type-specific gene expression increases with developmental age., W. Cai, J. Huang, Q. Zhu, B. Li, D. Seruggia, P. Zhou, M. Nguyen, Y. Fujiwara, H. Xie, Z. Yang, D. Hong, P. Ren, J. Xu, W. Pu, G.-C. Yuan, S. H. Orkin, 2020
Dissecting super-enhancer hierarchy based on chromatin interactions., J. Huang, K. Li, W. Cai, X. Liu, Y. Zhang, S. H. Orkin, J. Xu, G.-C. Yuan, 2018
Multi-scale chromatin state annotation using a hierarchical hidden Markov model., E. Marco, W. Meuleman, J. Huang, K. Glass, L. Pinello, J. Wang, M. Kellis, G.-C. Yuan, 2017
Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis., J. Huang, X. Liu, D. Li, Z. Shao, H. Cao, Y. Zhang, E. Trompouki, T. V. Bowman, L. I. Zon, G.-C. Yuan, S. H. Orkin, J. Xu, 2016
Predicting chromatin organization using histone marks., J. Huang, E. Marco, L. Pinello, G.-C. Yuan, 2015
Systematic prediction of pharmacodynamic drug-drug interactions through protein-protein-interaction network., J. Huang, C. Niu, C. D. Green, L. Yang, H. Mei, J.-D. J. Han, 2013
eResponseNet: a package prioritizing candidate disease genes through cellular pathways., J. Huang, Y. Liu, W. Zhang, H. Yu, J.-D. J. Han, 2011

Epigenetics Mammalian Development Cancer Bioinformatics Genomics Crispr Gene Editing Single-Cell Analysis Enhancer Networks Drug Targets

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