Professor | Tianhui Hu | Asia Growth Partners

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Name	Tianhui Hu
Contact Information	thu@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Tianhui Hu

Contact Information

thu@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	1991-1995 Bachelor of Science in Biochemistry: Xiamen University 1995-2000 Doctor of Science in Biophysics: Chinese Academy of Sciences New Century Excellent Talents in University by Ministry of Education
Work Experience	2000-2004 - Howard Hughes Medical Institute - Postdoctoral Researcher 2004-2008 - Vanderbilt University Medical Center - Postdoctoral Researcher 2008-Present - Xiamen University School of Medicine - Professor
Awards	2014: Xiamen Science and Technology Progress Award, Second Prize 2012: Xiamen Key Introduced Talent 2010: Fujian Outstanding Youth Fund Recipient 2009: New Century Excellent Talents in University by Ministry of Education

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

1991-1995 Bachelor of Science in Biochemistry: Xiamen University
1995-2000 Doctor of Science in Biophysics: Chinese Academy of Sciences
New Century Excellent Talents in University by Ministry of Education

Work Experience

2000-2004 - Howard Hughes Medical Institute - Postdoctoral Researcher
2004-2008 - Vanderbilt University Medical Center - Postdoctoral Researcher
2008-Present - Xiamen University School of Medicine - Professor

Awards

2014: Xiamen Science and Technology Progress Award, Second Prize
2012: Xiamen Key Introduced Talent
2010: Fujian Outstanding Youth Fund Recipient
2009: New Century Excellent Talents in University by Ministry of Education

Areas of Focus	Diagnosis and treatment of gastrointestinal tumors Development of new diagnostic reagents and therapeutic drugs for colorectal cancer
Publications	ULK1 phosphorylates Exo70 to suppress breast cancer metastasis., Liyuan Mao, Yan-yan Zhan, Bin Wu, Qiang Yu, Liang Xu, Xiaoting Hong, Linhai Zhong, Panying Mi, Li Xiao, Xinquan Wang, Hanwei Cao, Wenqing Zhang, Binbin Chen, Jingzhou Xiang, Kunrong Mei, Ravi Radhakrishnan, Wei Guo, and Tianhui Hu, 2020 Structure-Activity Relationship Study Enables the Discovery of a Novel Berberine Analogue as RXRα Activator to Inhibit Colon Cancer., Beibei Xu, Xunjin Jiang, Jing Xiong, Lan Jun, Linhai Zhong, Xinquan Wang, Hanwei Cao, Yanyan Zhan, Yandong Zhang and Tianhui Hu, 2020 Merging C–H Vinylation with Switchable 6#-Electrocyclizations for Divergent Heterocycle Synthesis., Xunjin Jiang, Zhixiong Zeng, Yuhui Hua, Beibei Xu, Yang Shen, Jing Xiong, Huijuan Qiu, Tianhui Hu and Yandong Zhang, 2020 High Expression of Tob1 Indicates Poor Survival Outcome and Promotes Tumor Progression via a Wnt Positive Feedback Loop in Colon Cancer., Dandan Li, Li Xiao, Yuetan Ge, Yu Fu, Wenqing Zhang, Hanwei Cao, Binbin Chen, Haibin Wang, Yan-yan Zhan, and Tianhui Hu, 2018 Berberine binds RXRα to suppress b-catenin signaling in colon cancer cells., Hang Ruan, Yan-yan Zhan, Jihuan Hou, Beibei Xu, Binbin Chen, Yuan Tian, Danhong Wu, Yujie Zhao, Youyu Zhang, Xiong Chen, Panying Mi, Lianru Zhang, Senyan Zhang, Xinquan Wang, Hanwei Cao, Wenqing Zhang, Haibo Wang, Haitao Li, Ying Su, Xiao-kun Zhang, Tianhui Hu, 2017 Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth., Dandan Li, Youyu Zhang, Kun Liu, Yujie Zhao, Beibei Xu, Liang Xu, Li Tan, Yuan Tian, Cunxi Li, Wenqing Zhang, Hanwei Cao, Yan-yan Zhan, Tianhui Hu, 2017 Exo70 is an independent prognostic factor in colon cancer., Li, Xiao, Kaifeng Zheng, Xia Lv, Jihuan Hou, Liang Xu, Yujie Zhao, Fei Song, Yaqiong Fan, Hanwei Cao, Wenqing Zhang, Xiaoting Hong, Yan-yan Zhan, and Tianhui Hu, 2017 Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF-β signaling pathway., Youyu Zhang, Lixing Huang, Yuejie Zhao, Tianhui Hu, 2017 Protecting-Group-Free Total Synthesis of (-)-Jiadifenolide: Development of a [4 + 1] Annulation toward Multisubstituted Tetrahydrofurans., Yang Shen, Linbin Li, Zhisheng Pan, Yinglu Wang, Jundong Li, Kuangyu Wang, Xiance Wang, Youyu Zhang, Tianhui Hu, and Yandong Zhang, 2015 Matrine Induces Caspase-Independent Program Cell Death in Hepatocellular Carcinoma through Bid-Mediated Nuclear Translocation of Apoptosis Inducing Factor., Huan Zhou, Minying Xu, Ya Gao, Zhigang Deng, Hanwei Cao, Wenqing Zhang, Qiao Wang, Bing Zhang, Gang Song, Yanyan Zhan, Tianhui Hu, 2014

Areas of Focus

Diagnosis and treatment of gastrointestinal tumors
Development of new diagnostic reagents and therapeutic drugs for colorectal cancer

Publications

ULK1 phosphorylates Exo70 to suppress breast cancer metastasis., Liyuan Mao, Yan-yan Zhan, Bin Wu, Qiang Yu, Liang Xu, Xiaoting Hong, Linhai Zhong, Panying Mi, Li Xiao, Xinquan Wang, Hanwei Cao, Wenqing Zhang, Binbin Chen, Jingzhou Xiang, Kunrong Mei, Ravi Radhakrishnan, Wei Guo, and Tianhui Hu, 2020
Structure-Activity Relationship Study Enables the Discovery of a Novel Berberine Analogue as RXRα Activator to Inhibit Colon Cancer., Beibei Xu, Xunjin Jiang, Jing Xiong, Lan Jun, Linhai Zhong, Xinquan Wang, Hanwei Cao, Yanyan Zhan, Yandong Zhang and Tianhui Hu, 2020
Merging C–H Vinylation with Switchable 6#-Electrocyclizations for Divergent Heterocycle Synthesis., Xunjin Jiang, Zhixiong Zeng, Yuhui Hua, Beibei Xu, Yang Shen, Jing Xiong, Huijuan Qiu, Tianhui Hu and Yandong Zhang, 2020
High Expression of Tob1 Indicates Poor Survival Outcome and Promotes Tumor Progression via a Wnt Positive Feedback Loop in Colon Cancer., Dandan Li, Li Xiao, Yuetan Ge, Yu Fu, Wenqing Zhang, Hanwei Cao, Binbin Chen, Haibin Wang, Yan-yan Zhan, and Tianhui Hu, 2018
Berberine binds RXRα to suppress b-catenin signaling in colon cancer cells., Hang Ruan, Yan-yan Zhan, Jihuan Hou, Beibei Xu, Binbin Chen, Yuan Tian, Danhong Wu, Yujie Zhao, Youyu Zhang, Xiong Chen, Panying Mi, Lianru Zhang, Senyan Zhang, Xinquan Wang, Hanwei Cao, Wenqing Zhang, Haibo Wang, Haitao Li, Ying Su, Xiao-kun Zhang, Tianhui Hu, 2017
Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth., Dandan Li, Youyu Zhang, Kun Liu, Yujie Zhao, Beibei Xu, Liang Xu, Li Tan, Yuan Tian, Cunxi Li, Wenqing Zhang, Hanwei Cao, Yan-yan Zhan, Tianhui Hu, 2017
Exo70 is an independent prognostic factor in colon cancer., Li, Xiao, Kaifeng Zheng, Xia Lv, Jihuan Hou, Liang Xu, Yujie Zhao, Fei Song, Yaqiong Fan, Hanwei Cao, Wenqing Zhang, Xiaoting Hong, Yan-yan Zhan, and Tianhui Hu, 2017
Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF-β signaling pathway., Youyu Zhang, Lixing Huang, Yuejie Zhao, Tianhui Hu, 2017
Protecting-Group-Free Total Synthesis of (-)-Jiadifenolide: Development of a [4 + 1] Annulation toward Multisubstituted Tetrahydrofurans., Yang Shen, Linbin Li, Zhisheng Pan, Yinglu Wang, Jundong Li, Kuangyu Wang, Xiance Wang, Youyu Zhang, Tianhui Hu, and Yandong Zhang, 2015
Matrine Induces Caspase-Independent Program Cell Death in Hepatocellular Carcinoma through Bid-Mediated Nuclear Translocation of Apoptosis Inducing Factor., Huan Zhou, Minying Xu, Ya Gao, Zhigang Deng, Hanwei Cao, Wenqing Zhang, Qiao Wang, Bing Zhang, Gang Song, Yanyan Zhan, Tianhui Hu, 2014

Gastrointestinal Tumors Diagnosis Treatment Wnt Signaling Pathway Egfr Nf-Κb Molecular Mechanism Colorectal Cancer Traditional Chinese Medicine Targeted Therapy

Ying Yuan - Zhejiang University

Zhangfa Song - Zhejiang University

Xiao Xu - Zhejiang University

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