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Xiu Qin Xu
Medical School
Xiamen University
Fujian
Language: Chinese, English
Stem Cells
Differentiation
Cardiomyocytes
Regenerative Medicine
Molecular Mechanisms
Rna Binding Proteins
Disease Modeling
Nanotechnology
Biomedical Applications
Gene Regulation
Areas of Focus
- Pluripotent Stem Cell Differentiation
- Molecular Cardiology
Work Experience
- 2001-2004: Research Fellow, Genome Institute of Singapore
- 2004-2007: Senior Scientist, International Embryonic Stem Cell Company
- 2007-2011: Head of Stem Cell Group, Singapore Institute of Medical Biology
- 2010-present: Distinguished Professor, Xiamen University School of Medicine, Deputy Director of Stem Cell and Regenerative Medicine Institute
Academic Background & Achievements
- 1983-1987: Bachelor's in Microbiology, Xiamen University
- 1987-1990: Master's in Biochemistry, Fujian Normal University
- 1998-2001: PhD in Molecular Biology, National University of Singapore
- Fujian Province 'Double Hundred Plan' Talent
- Fujian Province Science and Technology Innovation Leading Talent
Publications
- Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein, Yu Lin, Kar Tong Tan, Jing Liu, Xu Kong, Zhengrong Huang, Xiu Qin Xu, 2017
- Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes, Liu, J., Kong, X., et al, and Xu, XQ, 2017
- Rbm24 regulates alternative splicing switch in Embryonic stem cell cardiac lineage differentiation, Zhang, T., Lin, Y., Liu, J., Zhang, Z.G., Fu, W., Guo, L.Y., Pan, L., Kong, X., Zhang, M.K., Lu, Y.H., Zhang, R.H. Qiang, X., Wei, H.L., Xu, X.Q., 2016
- Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles, J Liu, L Wang, J Cao, Y Huang, Y Lin, XY Wu, Z Wang, F Zhang, XQ Xu and G Liu, 2014
- Perspective From the Heart: The Potential of Human Pluripotent Stem Cell-Derived Cardiomyocytes, Xiu Qin Xu and William Sun, 2013
- Cardiomyocytes from Human Embryonic Stem Cells, Xiu Qin Xu, Manasi Nandihalli, Kar Tong Tan, William Sun, 2013
- RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility, Kar Lai Poon, Kar Tong Tan, Yang Ye Wei, Chee Peng Ng, Alan Colman, Vladimir Korzh, Xiu Qin Xu, 2012
- MicroRNA-24 regulates cardiac fibrosis after myocardial infarction, Wang, J., Huang, W., Xu, R., Nie, Y., Cao, X., Meng, J., Xu, X., Hu, S., and Zheng, Z., 2012
- Global Expression Profile of Highly Enriched Cardiomyocytes Derived from Human Embryonic Stem Cells, Xiu Qin Xu, SY Soo, W Sun, R Zweigerdt, 2009
- Chemically Defined Medium supporting Differentiation of Human Embryonic Stem Cells to Cardiomyocytes, Xiu Qin Xu, R Graichen, C Mummery, Alan Colman, R Zweigerdt, B. Davidson, 2008
- Highly Enriched Cardiomyocytes from Human Embryonic Stem Cells, Xiu Qin Xu, R Zweigerdt, A Colman, and W Sun, 2008
- Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK, R Graichen, Xiu Qin Xu, SY Soo, SC Tham, C Mummery, A Colman, R Zweigerdt, BP Davidson, 2008
- HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells, KM, Mohankumar, Xiu Qin Xu, LD Miller, ET Liu, PD Gluckman, PE Lobie, 2007
- Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells, Freund, C., D. Ward-van Oostwaard, J. Monshouwer-Kloots, S. van den Brink, M. van Rooijen, X.Q. Xu, R. Zweigerdt, C. Mummery, and R. Passier, 2008
- Whole Genome Analysis of Human Neural Stem Cells Derived from Embryonic Stem Cells and Stem and Progenitor Cells Isolated from Fetal Tissue, S Shin, Y Sun, Y Liu, Xiu Qin Xu, B Davidson, E Reubinoff, S Goldman, Z Ming, M Rao, J Chestnut, 2007
- Recursive SVM Feature Selection and Sample Classification for Proteomics Mass-Spectrometry and microarray Data, X Zhang X Lu, Xiu-Qin Xu, HC Leung, WH. Wong, 2006
- Gene expression profiling to identify oncogenic determinants of autocrine human growth hormone (hGH) in human mammary carcinoma, Xiu Qin Xu, BS Emerald, EL Goh, N. Kannan, LD Miller, PD Gluckman, Edison T Liu and P Lobie, 2005
- Transcriptome Profiling of Human and Murine ESCs Identifies Divergent Paths Required to Maintain the Stem Cell State, CL Wei, P Robson L. Stanton, SK Lim, Xiu-Qin Xu, Y J Ruan, M Rao. Bing Lim, 2005
- Molecular Classification of Liver Cirrhosis in Rat Model by Proteomics and Bioinformatics, Xiu-Qin Xu, X Lu, X. Zhang, JS. Liu, WH Wong, A Asperger, S Deininger, CK Leow, HC Leung, 2004
- Feedback regulation of Agrobacterium catalase gene katA involved in Agrobacterium-plant interaction, Xiu Q. Xu and S. Q. Pan, 2001
- An Agrobacterium catalase is a virulence factor involved in tumorigenesis, Xiu. Q. Xu and S. Q. Pan, 2000
