Areas of Focus
- Vesicle transport and spatial-temporal dynamics of signaling lipids, regulation and disease
- Live cell single-molecule fluorescence imaging technology
Work Experience
- 2017-08~2019-03, Harvard Medical School and Boston Children's Hospital, Lecturer
- 2013-07~2017-07, Harvard Medical School and Boston Children's Hospital, Postdoctoral Researcher
- 2008-09~2013-07, Peking University, PhD Student
- 2003-09~2008-07, Peking University Medical School, Bachelor Student
Academic Background & Achievements
- 2008-09--2013-07 PhD: Peking University
- 2003-09--2008-07 Bachelor: Peking University Medical School
Publications
- CRISPR-Cas9 genome editing for tagging endogenous proteins with fluorescent tags, Corresponding Author, 2023
- Crosstalk between adrenergic receptors and catalytic receptors, Corresponding Author, 2023
- Geometric constraint-triggered collagen expression mediates bacterial-host adhesion, 13th Author, 2023
- Structure and dynamics of the EGFR/HER2 heterodimer, Corresponding Author, 2023
- The Salmonella Typhimurium effector SpvB subverts host membrane trafficking by targeting clathrin and AP-1, Corresponding Author, 2023
- The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling, Corresponding Author, 2021
- Inherited nuclear pore substructures template post-mitotic pore assembly, 4th Author, 2021
- Dynamics of Auxilin 1 and GAK in clathrin-mediated traffic, 1st Author, 2020
- Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface, 15th Author, 2020
- Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis, 5th Author, 2018
- Single-molecule imaging and tracking of molecular dynamics in living cells, Corresponding Author, 2017
- Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation, 1st Author, 2017
- Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic, Corresponding Author, 2017
- Single-molecule imaging reveals the stoichiometry change of epidermal growth factor receptor during transactivation by β2-adrenergic receptor, 2nd Author, 2017
- Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion, 3rd Author, 2016
- mAbp1/HIP-55 is essential for the scission of clathrin-coated pits by regulating dynamin-actin interaction, 1st Author, 2015
- Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes, 1st Author, 2015
- Single-molecule imaging revealed enhanced dimerization of transforming growth factor beta type II receptors in hypertrophic cardiomyocytes, 1st Author, 2011
- Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes, 1st Author, 2011
- Intercellular Transportation of Quantum Dots Mediated by Membrane Nanotubes, 1st Author, 2010
- Blood lead levels of children and its trend in China, 1st Author, 2009
- Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development, 10th Author
Awards
- Harvard Chinese Life Science Outstanding Academic Award (2018)
- Beijing Outstanding Graduate (2013)
- Peking University Outstanding Graduate (2013)
