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Xiaohong Xu
Veterinary Medicine
Jilin University
Jilin
Language: Chinese, English
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Epidemic Diseases Zoonotic Diseases Pathogenesis Pathogen Structure Function Analysis Newcastle Disease Virus Exosomes Virus-Like Particles Reverse Genetics Vaccine Development
Areas of Focus
  • Major animal epidemic diseases and zoonotic disease pathogenesis, pathogen structure and function analysis
  • Research on exosomes secreted by cells infected with Newcastle disease virus (NDV Ex)
  • Research on Newcastle disease virus-like particles (NDV VLPs)
  • Reverse genetics system related to Newcastle disease virus
Work Experience
  • 2021.9-2023.3 Lecturer, College of Veterinary Medicine, Jilin University
  • 2023.3-present Associate Professor, College of Veterinary Medicine, Jilin University
Academic Background & Achievements
  • 2007-2012 Bachelor of Veterinary Science, China Agricultural University
  • 2012-2014 Master of Science, UK Royal Agricultural University, Supervisor: Prof. Meriel Moore-Colyer
  • 2016-2019 PhD in Veterinary Medicine, Jilin University, Supervisor: Professor Zhuang Ding
Publications
  • Evaluation of the safety and protection efficacy of an attenuated genotype VIINewcastle disease virusstrain as a candidate vaccine, Xiaohong Xu et al., 2020
  • ChimericNewcastle disease virus-like particles containing DC-binding peptide-fused haemagglutininprotect chickens from virulent Newcastle disease virus and H9N2 avian influenza virus challenge, Xiaohong Xu et al., 2020
  • Newcastle disease virus-like particles containing the Brucella BCSP31 protein induce dendritic cell activation and protect mice against virulent Brucella challenge, Xiaohong Xu et al., 2019
  • Detection of viral components in exosomes derived from NDV-infected DF-1 cells and their promoting ability invirus replication, Xiaohong Xu et al., 2019
  • A novel recombinant attenuatedNewcastle disease virusexpressing H9 subtype hemagglutinin protected chickens from challenge by genotype VII virulent Newcastle disease virus and H9N2 avian influenza virus, Xiaohong Xu et al., 2019
  • A genotype VIINewcastle disease virus-like particles confer full protection with reduced virus load and decreasedvirus shedding, Xiaohong Xu et al., 2019
  • Newcastle disease virus-likeparticles induce DC maturation through TLR4/NF-kB pathway and facilitate DC migration by CCR7-CCL19/CCL21 axis, Xiaohong Xu et al., 2017
  • Identification and pathotypical analysis of a novel VIk sub-genotypeNewcastle disease virusobtained from pigeon in China, Xiaohong Xu et al., 2017
  • Dendritic cell-targeted recombinant Lactobacilli induce DC activation and T elicit specific immune responses against G57 genotype of avian H9N2 influenza virus infection, Xiaohong Xu et al., 2018
  • Newcastle disease virus-likeparticles induce dendritic cell maturation and enhance viral-specific immune response, Xiaohong Xu et al., 2017
  • Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern, Xiaohong Xu et al., 2021
  • NDV related exosome enhance NDV replication through exporting NLRX1 mRNA, Xiaohong Xu et al., 2021
  • Pathologic mechanism of Newcastle disease viruse, Xiaohong Xu et al., 2022
  • NDV inhibited IFN-βsecretion through impeding CHCHD10-mediated mitochondrial fusion to promote viral proliferation, Xiaohong Xu et al., 2024
  • Mitochondrial protein CHCHD10 inhibits NDV replication and reduces pathological changes, Xiaohong Xu et al., 2024
  • poly(I:C)刺激鸡胚胎成纤维细胞产生外泌体的抗新城疫病毒活性, Xiaohong Xu et al., 2018
  • 基因Ⅶ型新城疫病毒样颗粒作为疫苗候选株的免疫效果, Xiaohong Xu et al., 2017
  • GPI锚定蛋白介导嵌合新城疫病毒样颗粒的组装, Xiaohong Xu et al., 2017
  • 新城疫病毒样颗粒对树突状细胞成熟的影响, Xiaohong Xu et al., 2017
Awards
  • 2017 Excellent Award, Jilin University Graduate Science and Technology Paper Presentation Competition
  • 2017 Third Prize, Excellent Paper Report, Chinese Veterinary Infectious Diseases Conference
  • 2022 Third Prize, Jilin University Young Teachers Bilingual Teaching Competition
  • 2023 Second Prize, Jilin University Teaching Innovation Competition
  • 2022 First Prize, Bilingual Group, Jilin University College of Veterinary Medicine Young Teachers and Bilingual Teaching Competition
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