Professor | Qiaoran Xi | Asia Growth Partners

Name	Qiaoran Xi
Contact Information	xiqiaoran@tsinghua.edu.cn
Language ability	English, Chinese
Province	Beijing

Name

Qiaoran Xi

Contact Information

xiqiaoran@tsinghua.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1989-1993 Bachelor: Nanjing University, Biochemistry Department 1998-2004 PhD: New York University Medical School Postdoctoral Research: New York University Medical School, Sloan Kettering Cancer Center
Work Experience	2004-2005 - New York University Medical School - Postdoctoral Researcher 2006-2013 - Sloan Kettering Cancer Center - Postdoctoral Researcher 2013-Present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1989-1993 Bachelor: Nanjing University, Biochemistry Department
1998-2004 PhD: New York University Medical School
Postdoctoral Research: New York University Medical School, Sloan Kettering Cancer Center

Work Experience

2004-2005 - New York University Medical School - Postdoctoral Researcher
2006-2013 - Sloan Kettering Cancer Center - Postdoctoral Researcher
2013-Present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor

Areas of Focus	Cell biology, biochemistry, molecular biology, genomics research on TGF-beta signaling in embryonic stem cell self-renewal, embryonic development, and cancer
Publications	Fimepinostat impairs NFκB and PI3K/AKT signaling and enhances gemcitabine efficacy in H3K27M-mutated diffuse intrinsic pontine glioma, Wang D, Yan K, Yu H, Li H, Zhou W, Hong Y, Guo S, Wang Y, Xu Chen, Pan C, Tang Y, Liu N, Wu W, Zhang L, Xi Q, 2024 BMP signaling in cancer stemness and differentiation, Zhou W, Yan K, Xi Q, 2023 Recruitment of TRIM33 to cell‐context specific PML nuclear bodies regulates nodal signaling in mESCs, Sun H, Chen Y, Yan K, Shao Y, Zhang Q, Lin Y, Xi Q, 2023 LncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells, Kong X, Yan K, Deng P, Fu H, Sun H, Huang W, Jiang S, Dai J, Zhang Q, Liu J, Xi Q, 2022 Context-dependent tumor suppressive BMP signaling in Diffuse Intrinsic Pontine Glioma regulates stemness through epigenetic regulation of CXXC5, Sun Y, Yan K, Wang Y, Xu C, Wang D, Zhou W, Guo S, Han Y, Tang L, Shao Y, Shan S, Zhang Q, Tang Y, Zhang L, Xi Q, 2022 HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs, Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q, 2022 A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells, Fu H, Wang T, Kong X, Yan K, Yang Y, Cao J, Yuan Y, Wang N, Kee K, Lu Z, Xi Q, 2022 A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells, Zuo F, Jiang J, Fu H, Yan K, Liefke R, Zhang J, Hong Y, Chang Z, Liu N, Wang Z, Xi Q, 2022 H3K18ac primes mesendodermal differentiation upon nodal signaling, Luo M, Bai J, Liu B, Yan P, Zuo F, Sun H, Sun Y, Xu X, Song Z, Yang Y, Massagué J, Lan X, Lu Z, Chen YG, Deng H, Xie W, Xi Q, 2019 Potent anti-tumor efficacy of palbociclib in H3.3K27M-mutant diffuse intrinsic pontine glioma, Sun Y, Sun Y, Yan K, Li Z, Xu C, Geng Y, Pan C, Chen X, Zhang l, Xi Q, 2019 The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin, Tian W, Yan P, Xu N, Chakravorty A, Liefke R, Xi Q, Wang Z, 2019 Crosstalk between TGF-β signaling and epigenome, Bai J, Xi Q, 2018 Role of TRIM33 in Wnt signaling during mesendoderm differentiation, Xia X, Zuo F, Luo M, Sun Y, Bai J, Xi Q, 2017 TGF-β control of stem cell differentiation genes, Massagué J, Xi Q, 2012 A poised chromatin platform for TGFβ access to master regulators, Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang L, Liu JX, Kim H, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massagué J, 2011

Areas of Focus

Cell biology, biochemistry, molecular biology, genomics research on TGF-beta signaling in embryonic stem cell self-renewal, embryonic development, and cancer

Publications

Fimepinostat impairs NFκB and PI3K/AKT signaling and enhances gemcitabine efficacy in H3K27M-mutated diffuse intrinsic pontine glioma, Wang D, Yan K, Yu H, Li H, Zhou W, Hong Y, Guo S, Wang Y, Xu Chen, Pan C, Tang Y, Liu N, Wu W, Zhang L, Xi Q, 2024
BMP signaling in cancer stemness and differentiation, Zhou W, Yan K, Xi Q, 2023
Recruitment of TRIM33 to cell‐context specific PML nuclear bodies regulates nodal signaling in mESCs, Sun H, Chen Y, Yan K, Shao Y, Zhang Q, Lin Y, Xi Q, 2023
LncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells, Kong X, Yan K, Deng P, Fu H, Sun H, Huang W, Jiang S, Dai J, Zhang Q, Liu J, Xi Q, 2022
Context-dependent tumor suppressive BMP signaling in Diffuse Intrinsic Pontine Glioma regulates stemness through epigenetic regulation of CXXC5, Sun Y, Yan K, Wang Y, Xu C, Wang D, Zhou W, Guo S, Han Y, Tang L, Shao Y, Shan S, Zhang Q, Tang Y, Zhang L, Xi Q, 2022
HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs, Liang T, Bai J, Zhou W, Lin H, Ma S, Zhu X, Tao Q, Xi Q, 2022
A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells, Fu H, Wang T, Kong X, Yan K, Yang Y, Cao J, Yuan Y, Wang N, Kee K, Lu Z, Xi Q, 2022
A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells, Zuo F, Jiang J, Fu H, Yan K, Liefke R, Zhang J, Hong Y, Chang Z, Liu N, Wang Z, Xi Q, 2022
H3K18ac primes mesendodermal differentiation upon nodal signaling, Luo M, Bai J, Liu B, Yan P, Zuo F, Sun H, Sun Y, Xu X, Song Z, Yang Y, Massagué J, Lan X, Lu Z, Chen YG, Deng H, Xie W, Xi Q, 2019
Potent anti-tumor efficacy of palbociclib in H3.3K27M-mutant diffuse intrinsic pontine glioma, Sun Y, Sun Y, Yan K, Li Z, Xu C, Geng Y, Pan C, Chen X, Zhang l, Xi Q, 2019
The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin, Tian W, Yan P, Xu N, Chakravorty A, Liefke R, Xi Q, Wang Z, 2019
Crosstalk between TGF-β signaling and epigenome, Bai J, Xi Q, 2018
Role of TRIM33 in Wnt signaling during mesendoderm differentiation, Xia X, Zuo F, Luo M, Sun Y, Bai J, Xi Q, 2017
TGF-β control of stem cell differentiation genes, Massagué J, Xi Q, 2012
A poised chromatin platform for TGFβ access to master regulators, Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang L, Liu JX, Kim H, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massagué J, 2011

Cell Biology Biochemistry Molecular Biology Genomics Tgf-Beta Signaling Embryonic Stem Cells Self-Renewal Embryonic Development Cancer Gene Expression Regulation

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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