Areas of Focus
- Structural Biology
Work Experience
- 2000-2003 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Researcher
- 2003-2008 - Stanford University, USA - Postdoctoral Researcher
- 2008-2013 - Tsinghua University, School of Life Sciences - Associate Professor
- 2013-Present - Tsinghua University, School of Life Sciences - Professor
Academic Background & Achievements
- 1990-1995 Bachelor: Fudan University
- 1995-2000 PhD: Institute of Biophysics, Chinese Academy of Sciences
Publications
- Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2, Wang X* et al., 2022
- Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry, Wang X* et al., 2021
- Bat and pangolin coronavirus spike glycoprotein structures provide insights into sars-cov-2 evolution, Wang X* et al., 2021
- Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution, Wang X* et al., 2020
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor, Wang X* et al., 2020
- Structural definition of a neutralization epitope on the n-terminal domain of mers-cov spike glycoprotein, Wang X* et al., 2019
- Functional relevance of interleukin-1 receptor inter-domain flexibility for cytokine binding and signaling, Wang X* et al., 2019
- Structural definition of a unique neutralization epitope on the receptor-binding domain of mers-cov spike glycoprotein, Wang X* et al., 2018
- Cryo-em structure of the sars coronavirus spike glycoprotein in complex with its host cell receptor ace2, Wang X* et al., 2018
- Cryo-electron microscopy structures of the sars-cov spike glycoprotein reveal a prerequisite conformational state for receptor binding, Wang X* et al., 2017
- Potent neutralization of mers-cov by human neutralizing monoclonal antibodies to the viral spike glycoprotein, Wang X* et al., 2014
- Structure of mers-cov spike receptor-binding domain complexed with human receptor dpp4, Wang X* et al., 2013
- Structural basis for r-spondin recognition by lgr4/5/6 receptors, Wang X* et al., 2013
- Structural insights into the interaction of il-33 with its receptors, Wang X* et al., 2013
- Structural insights into the assembly and activation of il-1beta with its receptors, Wang X* et al., 2010
