Areas of Focus
- Universal regulatory mechanisms and rules of phase separation phenomena
- Biological significance of phase separation in autophagy, transcriptional regulation, and epigenetics
- Technology development and applications based on phase separation
Work Experience
- 2016-Present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor
Academic Background & Achievements
- 1996-2000 Bachelor: Peking University
- 2000-2002 Master: Hong Kong University of Science and Technology
- 2002-2009 PhD: University of Texas Southwestern Medical Center
- 2009-2010 Postdoctoral Researcher: University of Texas Southwestern Medical Center
- 2010-2015 Postdoctoral Researcher: University of Pennsylvania
Publications
- Dual-Role Transcription Factors Stabilize Intermediate Expression Levels, He J, Huo X, Pei G, Jia Z, Yan Y, Yu J, Qu H, Xie Y, Yuan J, Zheng Y, Hu Y, Shi M, You K, Li T, Ma T, Zhang M Q, Ding S, Li P, Li Y, 2024
- An all-in-one targeted protein degradation platform guided by degradation condensates-bridging bi-specific nanobodies, Jia W, Li W, Li Z, Li P, 2024
- Prevalent aberrant condensates of onco-fusion transcription factors and their dissolution as potential cancer therapy, Wang Y, Yu C, Pei G, Jia W, Li T, Li P, 2023
- Programming cell-surface signaling by phase-separation-controlled compartmentalization, Li R, Li T, Lu G, Cao Z, Chen B, Wang Y, Du J, Li P, 2022
- Histone H2B.8 compacts flowering plant sperm through chromatin phase separation, Buttress T, He S, Wang L, Zhou S, Saalbach G, Vickers M, Li G, Li P, Feng X, 2022
- Screening membraneless organelle participants with machine-learning models that integrate multimodal features, Chen Z, Hou C, Wang L, Yu C, Chen T, Shen B, Hou Y, Li P, Li T, 2022
- Myosin 1D and the branched actin network control the condensation of p62 bodies, Feng X, Du W, Ding M, Zhao W, Xirefu X, Ma M, Zhuang Y, Fu X, Shen J, Zhang J, Lei X, Sun D, Xi Q, Aisa Y, Chen Q, Li Y, Wang W, Huang S, Yu L, Li P, Mi N, 2022
- Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome, Xu W, Pei G, Liu H, Ju X, Wang J, Ding Q, Li P, 2021
- Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes, Fang X, Wang L, Ishikawa R, Li Y, Fiedler M, Liu F, Calder G, Rowan B, Weigel D, Li P, Dean C, 2019
- Phase transitions in the assembly of multivalent signalling proteins, Li P, Banjade S, Cheng HC, Kim S, Chen B, Guo L, Llaguno M, Hollingsworth JV, King DS, Banani SF, Russo PS, Jiang QX, Nixon BT, Rosen MK, 2012
Awards
- Vice Chairman of the Biophysical Society of China on Biomolecular Phase Separation and Transition
- Editorial Board Member of Molecular Cell
- Associate Editor of Biochemical Journal
- Reviewer for journals including Cell, Nature, Science
