Areas of Focus
- Epigenetics, Genomics, Developmental Biology
Work Experience
- 2008-2009 Postdoctoral Researcher: University of California, Los Angeles
- 2009-2013 Postdoctoral Researcher: Ludwig Cancer Research, University of California, San Diego
- 2013- Assistant Professor, Associate Professor, Professor: Tsinghua University
Academic Background & Achievements
- 1999-2003 Bachelor of Biological Sciences: Peking University
- 2003-2008 PhD in Molecular Biology: University of California, Los Angeles
- 2006-2008 Master of Statistics: University of California, Los Angeles
Publications
- Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos, Wei Xie et al., 2023
- NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos, Wei Xie et al., 2023
- OBOX regulates mouse zygotic genome activation and early development, Wei Xie et al., 2023
- Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation, Wei Xie et al., 2022
- Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development, Wei Xie et al., 2022
- Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting, Wei Xie et al., 2021
- The landscape of RNA Pol II binding reveals a step-wise transition during ZGA, Wei Xie et al., 2020
- Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance, Wei Xie et al., 2020
- Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency, Wei Xie et al., 2019
- Resetting histone modifications during human parental-to-zygotic transition, Wei Xie et al., 2019
- SETD2 regulates the maternal epigenome and embryonic development, Wei Xie et al., 2019
- Chromatin analysis in human early development reveals epigenetic transition during ZGA, Wei Xie et al., 2018
- Allelic reprogramming of 3D chromatin architecture during early mammalian development, Wei Xie et al., 2017
- Allelic reprogramming of the histone modification H3K4me3 in early mammalian development, Wei Xie et al., 2016
- The landscape of accessible chromatin in mammalian preimplantation embryos, Wei Xie et al., 2016
