Areas of Focus
- Free Radical Biology
- Bioinorganic Chemistry
Work Experience
- 2004.12 - Present: Huazhong University of Science and Technology, Chemistry Department, Professor
- 2001.9 - 2002.9: University of Texas Medical School at Houston, Integrative Biology & Pharmacology, Visiting Scientist
- 2000.6 - 2004.12: Huazhong University of Science and Technology, Chemistry Department, Associate Professor
- 1998.11 - 2000.6: Huazhong University of Science and Technology, Chemistry Department, Lecturer
Academic Background & Achievements
- 1995-1998 PhD: Huazhong University of Science and Technology
- Selected for the Ministry of Education's New Century Excellent Talents Support Plan (2005)
Publications
- Nitration of hIAPP promotes its toxic oligomer formation and exacerbates its toxicity towards INS-1 cells, Zhonghong Gao, Hailing Li, 2019
- Nitration of amyloid-β peptide (1-42) as a protective mechanism for the amyloid-β peptide (1-42) against copper ion toxicity, Zhonghong Gao, Hailing Li, 2019
- Copper binding induces nitration of NPY under nitrative stress: complicating the role of NPY in Alzheimer's Disease, Zhonghong Gao, Hailing Li, 2018
- 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinato iron(III) chloride (FeTPPS), a peroxynitrite decomposition catalyst, catalyzes protein tyrosine nitration in the presence of hydrogen peroxide and nitrite, Zhonghong Gao, Hailing Li, 2018
- Study on the detoxification mechanisms to 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrinato iron(III) chloride (FeTPPS), an efficient pro-oxidant of heme water-soluble analogue, Zhonghong Gao, Hailing Li, 2018
- Hemin-graphene derivatives with increased peroxidase activities restrain protein tyrosine nitration, Zhonghong Gao, Hailing Li, 2017
- NPY binds with heme to form a NPY-heme complex: enhances free heme’s peroxidase and promotes NPY nitration and inactivation, Zhonghong Gao, Hailing Li, 2017
- Strong inhibitory effect of heme on hIAPP fibrillation, Zhonghong Gao, Hailing Li, 2017
- Interaction of glyceraldehyde-3-phosphate dehydrogenase and heme: the relevance of its biological function, Zhonghong Gao, Hailing Li, 2017
- Nitration of tyrosine residue Y10 of Aβ1-42 significantly inhibits its aggregation and cytotoxicity, Zhonghong Gao, Hailing Li, 2017
- Triosephosphate Isomerase Tyrosine Nitration Induced by Heme-NaNO2-H2O2 or Peroxynitrite: Effects of Different Natural Phenolic Compounds, Zhonghong Gao, Hailing Li, 2017
Awards
- 2005: New Century Excellent Talents
