Professor | Yi Wen | Asia Growth Partners

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Name	Yi Wen
Contact Information	wyi@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

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Name

Yi Wen

Contact Information

wyi@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Life Sciences
Academic Background & Achievements	2013-Present: Professor at Zhejiang University, School of Life Sciences 2018-Present: Jointly appointed Professor at the First Affiliated Hospital of Zhejiang University School of Medicine 2008-2012: Postdoctoral Researcher at California Institute of Technology, USA 2002-2008: PhD from The Ohio State University, USA 1998-2002: Bachelor from Fudan University
Work Experience	2013-Present - Zhejiang University, School of Life Sciences - Professor 2018-Present - First Affiliated Hospital of Zhejiang University School of Medicine - Jointly appointed Professor 2008-2012 - California Institute of Technology, USA - Postdoctoral Researcher
Awards	2024: Horase S. Isbell Award from the American Chemical Society's Division of Carbohydrate Chemistry 2023: National Natural Science Foundation of China 'Outstanding Young Scientist' 2022: 'Huiyong Zheng Carbohydrate Science Award' - Young Innovator Award 2021: Chinese Society of Biotechnology 'Shu Zheng Sugar Science Award' - Outstanding Young Award 2021: Mizutani Foundation for Glycoscience Academic Research Award 2013: International Glycoconjugate Organization Young Glycoscientist 2014: National Natural Science Foundation of China 'Excellent Young Scientist' 2013: National High-Level Talents Project (Youth) 2010: Postdoctoral Fellowship, Tobacco-Related Disease Program, California, USA

University/Lab Affiliation and Title

Zhejiang University

Faculty

Life Sciences

Academic Background & Achievements

2013-Present: Professor at Zhejiang University, School of Life Sciences
2018-Present: Jointly appointed Professor at the First Affiliated Hospital of Zhejiang University School of Medicine
2008-2012: Postdoctoral Researcher at California Institute of Technology, USA
2002-2008: PhD from The Ohio State University, USA
1998-2002: Bachelor from Fudan University

Work Experience

2013-Present - Zhejiang University, School of Life Sciences - Professor
2018-Present - First Affiliated Hospital of Zhejiang University School of Medicine - Jointly appointed Professor
2008-2012 - California Institute of Technology, USA - Postdoctoral Researcher

Awards

2024: Horase S. Isbell Award from the American Chemical Society's Division of Carbohydrate Chemistry
2023: National Natural Science Foundation of China 'Outstanding Young Scientist'
2022: 'Huiyong Zheng Carbohydrate Science Award' - Young Innovator Award
2021: Chinese Society of Biotechnology 'Shu Zheng Sugar Science Award' - Outstanding Young Award
2021: Mizutani Foundation for Glycoscience Academic Research Award
2013: International Glycoconjugate Organization Young Glycoscientist
2014: National Natural Science Foundation of China 'Excellent Young Scientist'
2013: National High-Level Talents Project (Youth)
2010: Postdoctoral Fellowship, Tobacco-Related Disease Program, California, USA

Areas of Focus	Glycochemistry Tumor Biology Stem Cell Biology
Publications	O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1, Yi W., 2022 O-GlcNAcylation regulates epidermal growth factor receptor intracellular trafficking and signaling, Yi W., 2022 Spatiotemporal activation of protein O-GlcNAcylation in living cells, Yi W., 2022 One-step enzymatic labeling reveals a critical role of O-GlcNAcylation in cell-cycle progression and DNA damage response, Yi W., 2021 O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells, Yi W., 2020 O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth, Yi W., 2020 O-GlcNAcylation of core components of the translation initiation machinery regulates protein synthesis, Yi W., 2019 An isotope-coded photocleavable probe for quantitative profiling of protein O-GlcNAcylation, Yi W., 2019 O-GlcNAcylation, a sweet link to pathology of diseases, Yi W., 2019 Redox controlled site-specific α2,6-sialylation, Yi W., 2019 Imaging of protein-specific glycosylation by glycan metabolic tagging and in situ proximity ligation, Yi W., 2017 Chemical remodeling cell surface glycans for immunotargeting of tumor cells, Yi W., 2017 Targeting tumor cells by natural anti-carbohydrate antibodies using rhamnose-functionalized liposomes, Yi W., 2016 O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth, Yi W., 2015 A Tandem Enzymatic Approach for Detecting and Imaging Tumor-Associated TF Antigen Disaccharide, Yi W., 2014 Regulation of Cancer Metabolism by O-GlcNAcylation, Yi W., 2014 Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism, Yi W., 2012 Chemoenzymatic Probes for Detecting and Imaging Fucosea(1,2)Galactose Glycan Biomarkers, Yi W., 2012 In Vitro Bacterial Polysaccharide Biosynthesis: Defining the Functions of Wzy and Wzz, Yi W., 2010 Remodeling Bacterial Polysaccharides by Metabolic Pathway Engineering, Yi W., 2009

Areas of Focus

Glycochemistry
Tumor Biology
Stem Cell Biology

Publications

O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1, Yi W.*, 2022
O-GlcNAcylation regulates epidermal growth factor receptor intracellular trafficking and signaling, Yi W.*, 2022
Spatiotemporal activation of protein O-GlcNAcylation in living cells, Yi W.*, 2022
One-step enzymatic labeling reveals a critical role of O-GlcNAcylation in cell-cycle progression and DNA damage response, Yi W.*, 2021
O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells, Yi W.*, 2020
O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth, Yi W.*, 2020
O-GlcNAcylation of core components of the translation initiation machinery regulates protein synthesis, Yi W.*, 2019
An isotope-coded photocleavable probe for quantitative profiling of protein O-GlcNAcylation, Yi W.*, 2019
O-GlcNAcylation, a sweet link to pathology of diseases, Yi W.*, 2019
Redox controlled site-specific α2,6-sialylation, Yi W.*, 2019
Imaging of protein-specific glycosylation by glycan metabolic tagging and in situ proximity ligation, Yi W.*, 2017
Chemical remodeling cell surface glycans for immunotargeting of tumor cells, Yi W.*, 2017
Targeting tumor cells by natural anti-carbohydrate antibodies using rhamnose-functionalized liposomes, Yi W.*, 2016
O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth, Yi W.*, 2015
A Tandem Enzymatic Approach for Detecting and Imaging Tumor-Associated TF Antigen Disaccharide, Yi W.*, 2014
Regulation of Cancer Metabolism by O-GlcNAcylation, Yi W.*, 2014
Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism, Yi W.*, 2012
Chemoenzymatic Probes for Detecting and Imaging Fucosea(1,2)Galactose Glycan Biomarkers, Yi W.*, 2012
In Vitro Bacterial Polysaccharide Biosynthesis: Defining the Functions of Wzy and Wzz, Yi W.*, 2010
Remodeling Bacterial Polysaccharides by Metabolic Pathway Engineering, Yi W.*, 2009

Glycosylation Biocompatibility Chemical Biology Disease Progression Stem Cell Differentiation Enzyme Research Click Chemistry Cellular Metabolism Tumor Proliferation Immune Therapy

Wei Wei - Nanjing University

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