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Daming Zhou
Life Science
Zhejiang University
Zhejiang
Language: English, Chinese
Virology
Host Interaction
Mechanisms
Antiviral
Drug Development
Biochemistry
Structural Biology
Molecular Biology
Therapeutics
Pathogens
Areas of Focus
- Viral and host interaction mechanisms
- Development of antiviral drugs
Work Experience
- 2013-2014 Research Assistant: Tianjin Protein Key Laboratory
- 2015 Assistant Researcher: Chengdu Pioneer Pharmaceutical Co., Ltd
- 2020-2023 Postdoctoral Researcher: Department of Structural Biology, University of Oxford
- 2024-Present Researcher: Zhejiang University, School of Life Sciences
Academic Background & Achievements
- 2009-2013 Bachelor in Biotechnology: Nankai University
- 2015-2020 PhD in Clinical Medicine: University of Oxford
- 2023 National Overseas High-level Talents
Publications
- Rapid escape of new SARS-CoV-2 Omicron variants from BA. 2-directed antibody responses, Dijokaite-Guraliuc, A., Das, R., Zhou, D.*, Ginn, H. M., Liu, C., Duyvesteyn, H. M., ... & Screaton, G. R., 2023
- Antibody escape of SARS-CoV-2 Omicron BA. 4 and BA. 5 from vaccine and BA. 1 serum, Tuekprakhon, A., Nutalai, R., Dijokaite-Guraliuc, A., Zhou D.*, Ginn, H. M., Selvaraj, M., ... & Screaton, G. R., 2022
- Potent cross-reactive antibodies following Omicron breakthrough in vaccinees, Nutalai, R., Zhou D.*, Tuekprakhon, A., Ginn, H. M., Supasa, P., Liu, C., ... & Screaton, G. R., 2022
- SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses, Dejnirattisai W., Huo J., Zhou D.*, Zahradník J., Supasa P., Liu C., ... & Screaton G. R., 2022
- Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2, Huang K. Y. A., Zhou D.*, Tan T. K., Chen C., Duyvesteyn H. M. E., Zhao Y., ... & Stuart D. I., 2022
- The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants, Liu C., Zhou D.*, Nutalai R., Duyvesteyn H. M. E., Tuekprakhon A., Ginn H. M., ... & Screaton G. R., 2021
- Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum, Liu C., Ginn H. M., Dejnirattisai W., Supasa P., Wang B., Tuekprakhon A., Nutalai R., Zhou D.*, ... & Screaton G. R., 2021
- Antibody evasion by the P.1 strain of SARS-CoV-2, Dejnirattisai W., Zhou D.*, Supasa P., Liu C., Mentzer A. J., Ginn H. M., ... & Screaton G. R., 2021
- Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera, Zhou D.*, Dejnirattisai W., Supasa P., Liu C., Mentzer A. J., Ginn H. M., ... & Screaton G. R., 2021
- Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera, Supasa P., Zhou D.*, Dejnirattisai W., Liu C., Mentzer A. J., Ginn H. M., ... & Screaton G. R., 2021
- The antigenic anatomy of SARS-CoV-2 receptor binding domain, Dejnirattisai W., Zhou D.*, Ginn H. M., Duyvesteyn H. M., Supasa P., Case J. B., ... & Screaton G. R., 2021
- Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71, Huang K. Y. A., Zhou D.*, Fry E. E., Kotecha A., Huang P. N., Yang S. L., ... & Stuart D. I., 2020
- Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient, Zhou D.*, Duyvesteyn H. M., Chen C. P., Huang C. G., Chen T. H., Shih S. R., ... & Huang K. Y. A., 2020
- Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10, Zhao Y., Zhou D.*, Ni T., Karia D., Kotecha A., Wang X., ... & Stuart D. I., 2020
- Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2, Zhou D.*, Zhao Y., Kotecha A., Fry E. E., Kelly J. T., Wang X., ... & Stuart D. I., 2018
Awards
- 2023 Award for Excellent Scheme, University of Oxford
- 2022 Horizon Prize for the Oxford nanobody team, Royal Society of Chemistry, UK
- 2021 Recognition Scheme Award for research on COVID, University of Oxford
