Professor | Li Xuanji | Asia Growth Partners

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Name	Li Xuanji
Contact Information	xuanji@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Li Xuanji

Contact Information

xuanji@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Life Sciences
Academic Background & Achievements	2014.12-2019.06 PhD in Microbiology, University of Copenhagen 2011.09-2014.06 Master's in Bioengineering, Shandong University, Microbial Technology National Key Laboratory
Work Experience	2024.03-present Researcher at Zhejiang University, Institute of Microbiology, Life Sciences College 2022.07-2024.02 Assistant Professor at University of Copenhagen, Department of Microbiology 2019.07-2022.06 Postdoctoral Researcher at University of Copenhagen, Department of Microbiology 2019.05-2019.06 Research Assistant at University of Copenhagen, Department of Microbiology

University/Lab Affiliation and Title

Zhejiang University

Faculty

Life Sciences

Academic Background & Achievements

2014.12-2019.06 PhD in Microbiology, University of Copenhagen
2011.09-2014.06 Master's in Bioengineering, Shandong University, Microbial Technology National Key Laboratory

Work Experience

2024.03-present Researcher at Zhejiang University, Institute of Microbiology, Life Sciences College
2022.07-2024.02 Assistant Professor at University of Copenhagen, Department of Microbiology
2019.07-2022.06 Postdoctoral Researcher at University of Copenhagen, Department of Microbiology
2019.05-2019.06 Research Assistant at University of Copenhagen, Department of Microbiology

Areas of Focus	Development and establishment of the gut microbiome in early human life (infants) Horizontal transfer of key functional genes in the human gut microbiome (e.g., antibiotic resistance genes, virulence genes) Influence of environmental factors (e.g., antibiotics, breastfeeding, environmental pollution) on the gut microbiome Relationship between the gut microbiome and health
Publications	Co-localization of antibiotic resistance genes is widespread in the infant gut and associates with an immature gut composition, Li, X., Brejnrod, A., Trivedi, U., Jonathan, T., Russel, J., & Sørensen, S. J., 2024 Interspecific interactions sustain structural keystone species in a multispecies biofilm benefitting plant growth, Yang, N., Røder, H.L., Wicaksono,W.A., Wassermann, B., Russsel, J., Li, X., Nesme, J., Berg, G., Sørensen, S.J.# and Burmølle, M.#, 2024 Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases, Lehtimäki, J., Gupta, S., Hjelmsø, M., Shah, S., Thorsen, J., Rasmussen, M.A., Soverini, M., Li, X., Russel, J., Trivedi, U. and Brix, S., 2023 Differential responses of the gut microbiome and resistome to antibiotic exposures in infants and adults, Li, X., Brejnrod, A., Thorsen, J., Zachariasen, T., Trivedi, U., Russel, J., Vestergaard, G.A., Stokholm, J., Rasmussen, M.A.# and Sørensen, S.J.#, 2023 The airway microbiota of neonates colonized with asthma-associated pathogenic bacteria, Thorsen, J., Li, X., Peng, S., Sunde, R. B., Shah, S. A., Bhattacharyya, M., ... & Stokholm, J.#, 2023 Metagenomic evidence for co-occurrence of antibiotic, biocide and metal resistance genes in pigs, Li, X., Rensing, C., Vestergaard, G., Arumugam, M., Nesme, J., Gupta, S., Brejnrod, A.D.# and Sørensen, S.J.#, 2022 The infant gut resistome associates with E. coli, environmental exposures, gut microbiome maturity, and asthma-associated bacterial composition, Li, X., Stokholm, J., Brejnrod, A., Vestergaard, G. A., Russel, J., Trivedi, U., ... & Sørensen, S.J.#, 2021 Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments, Mazhar, S.H., Li, X., Rashid, A., Su, J., Xu, J., Brejnrod, A.D., Su, J.Q., Wu, Y., Zhu, Y.G., Zhou, S.G. and Feng, R., Rensing, C.#, 2021 The microbiome of captive hamadryas baboons, Li, X., Trivedi, U., Brejnrod, A.D., Vestergaard, G., Mortensen, M.S., Bertelsen, M.F. and Sørensen, S.J.#, 2020 Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites, Li, X., Brejnrod, A.D., Ernst, M., Rykær, M., Herschend, J., Olsen, N.M.C., Dorrestein, P.C., Rensing, C.# and Sørensen, S.J.#, 2019 Papio spp. Colon microbiome and its link to obesity in pregnancy, Li, X., Rensing, C., Taylor, W.L., Costelle, C., Brejnrod, A.D., Ferry Jr, R.J., Higgins, P.B., Folli, F., Kottapalli, K.R., Hubbard, G.B., Dick Jr, E.J., Schlabritz‐Loutsevitch, N.#, 2018 Bacterial resistance to arsenic protects against protist killing, Hao, X., Li, X., Pal, C., Hobman, J., Larsson, D.G., Saquib, Q., Alwathnani, H.A., Rosen, B.P., Zhu, Y.G. and Rensing, C.#, 2017 Emergent bacterial community properties induce enhanced drought tolerance in Arabidopsis, Yang, N., Nesme, J., Røder, H.L., Li, X., Zuo, Z., Petersen, M., Burmølle, M.# and Sørensen, S.J.#, 2021 Antimicrobial activity of metals and metalloids, Li, Y.P., Ben Fekih, I., Chi Fru, E., Moraleda-Munoz, A., Li, X., Rosen, B.P., Yoshinaga, M. and Rensing, C.#, 2021 A community resource for paired genomic and metabolomic data mining, Schorn MA, Verhoeven S, Ridder L, Huber F, Acharya DD, Aksenov AA, ... Li X,.. van der Hooft JJ.#, 2021 Efficient Production of Pyruvate Using Metabolically Engineered Lactococcus lactis, Suo, F., Liu, J., Chen, J., Li, X., Solem, C. and Jensen, P.R.#, 2021 Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota, Gupta, S., Hjelmsø, M.H., Lehtimäki, J., Li, X., Mortensen, M.S., Russel, J., Trivedi, U., Rasmussen, M.A., Stokholm, J., Bisgaard, H. and Sørensen, S.J.#, 2020 A role for copper in protozoan grazing–two billion years selecting for bacterial copper resistance, Hao, X., Lüthje, F., Rønn, R., German, N.A., Li, X., Huang, F., Kisaka, J., Huffman, D., Alwathnani, H.A., Zhu, Y.G. and Rensing, C.#, 2016 Draft genome sequence of Se (IV)-reducing bacterium Pseudomonas migulae ES3-33, Li, X., Kot, W., Wang, D., Zheng, S., Wang, G., Hansen, L.H. and Rensing, C.#, 2015

Areas of Focus

Development and establishment of the gut microbiome in early human life (infants)
Horizontal transfer of key functional genes in the human gut microbiome (e.g., antibiotic resistance genes, virulence genes)
Influence of environmental factors (e.g., antibiotics, breastfeeding, environmental pollution) on the gut microbiome
Relationship between the gut microbiome and health

Publications

Co-localization of antibiotic resistance genes is widespread in the infant gut and associates with an immature gut composition, Li, X., Brejnrod, A., Trivedi, U., Jonathan, T., Russel, J., & Sørensen, S. J., 2024
Interspecific interactions sustain structural keystone species in a multispecies biofilm benefitting plant growth, Yang, N., Røder, H.L., Wicaksono,W.A., Wassermann, B., Russsel, J., Li, X., Nesme, J., Berg, G., Sørensen, S.J.# and Burmølle, M.#, 2024
Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases, Lehtimäki, J., Gupta, S., Hjelmsø, M., Shah, S., Thorsen, J., Rasmussen, M.A., Soverini, M., Li, X., Russel, J., Trivedi, U. and Brix, S., 2023
Differential responses of the gut microbiome and resistome to antibiotic exposures in infants and adults, Li, X., Brejnrod, A., Thorsen, J., Zachariasen, T., Trivedi, U., Russel, J., Vestergaard, G.A., Stokholm, J., Rasmussen, M.A.# and Sørensen, S.J.#, 2023
The airway microbiota of neonates colonized with asthma-associated pathogenic bacteria, Thorsen, J., Li, X., Peng, S., Sunde, R. B., Shah, S. A., Bhattacharyya, M., ... & Stokholm, J.#, 2023
Metagenomic evidence for co-occurrence of antibiotic, biocide and metal resistance genes in pigs, Li, X., Rensing, C., Vestergaard, G., Arumugam, M., Nesme, J., Gupta, S., Brejnrod, A.D.# and Sørensen, S.J.#, 2022
The infant gut resistome associates with E. coli, environmental exposures, gut microbiome maturity, and asthma-associated bacterial composition, Li, X., Stokholm, J., Brejnrod, A., Vestergaard, G. A., Russel, J., Trivedi, U., ... & Sørensen, S.J.#, 2021
Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments, Mazhar, S.H.*, Li, X.*, Rashid, A., Su, J., Xu, J., Brejnrod, A.D., Su, J.Q., Wu, Y., Zhu, Y.G., Zhou, S.G. and Feng, R., Rensing, C.#, 2021
The microbiome of captive hamadryas baboons, Li, X., Trivedi, U., Brejnrod, A.D., Vestergaard, G., Mortensen, M.S., Bertelsen, M.F. and Sørensen, S.J.#, 2020
Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites, Li, X., Brejnrod, A.D.*, Ernst, M., Rykær, M., Herschend, J., Olsen, N.M.C., Dorrestein, P.C., Rensing, C.# and Sørensen, S.J.#, 2019
Papio spp. Colon microbiome and its link to obesity in pregnancy, Li, X., Rensing, C., Taylor, W.L., Costelle, C., Brejnrod, A.D., Ferry Jr, R.J., Higgins, P.B., Folli, F., Kottapalli, K.R., Hubbard, G.B., Dick Jr, E.J., Schlabritz‐Loutsevitch, N.#, 2018
Bacterial resistance to arsenic protects against protist killing, Hao, X*., Li, X.*, Pal, C.*, Hobman, J., Larsson, D.G., Saquib, Q., Alwathnani, H.A., Rosen, B.P., Zhu, Y.G. and Rensing, C.#, 2017
Emergent bacterial community properties induce enhanced drought tolerance in Arabidopsis, Yang, N., Nesme, J., Røder, H.L., Li, X., Zuo, Z., Petersen, M., Burmølle, M.# and Sørensen, S.J.#, 2021
Antimicrobial activity of metals and metalloids, Li, Y.P., Ben Fekih, I., Chi Fru, E., Moraleda-Munoz, A., Li, X., Rosen, B.P., Yoshinaga, M. and Rensing, C.#, 2021
A community resource for paired genomic and metabolomic data mining, Schorn MA, Verhoeven S, Ridder L, Huber F, Acharya DD, Aksenov AA, ... Li X,.. van der Hooft JJ.#, 2021
Efficient Production of Pyruvate Using Metabolically Engineered Lactococcus lactis, Suo, F., Liu, J., Chen, J., Li, X., Solem, C. and Jensen, P.R.#, 2021
Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota, Gupta, S., Hjelmsø, M.H., Lehtimäki, J., Li, X., Mortensen, M.S., Russel, J., Trivedi, U., Rasmussen, M.A., Stokholm, J., Bisgaard, H. and Sørensen, S.J.#, 2020
A role for copper in protozoan grazing–two billion years selecting for bacterial copper resistance, Hao, X., Lüthje, F., Rønn, R., German, N.A., Li, X., Huang, F., Kisaka, J., Huffman, D., Alwathnani, H.A., Zhu, Y.G. and Rensing, C.#, 2016
Draft genome sequence of Se (IV)-reducing bacterium Pseudomonas migulae ES3-33, Li, X., Kot, W., Wang, D., Zheng, S., Wang, G., Hansen, L.H. and Rensing, C.#, 2015

Infant Gut Microbiome Development Establishment Horizontal Gene Transfer Antibiotic Resistance Environmental Factors Health Breastfeeding Pollution

Yuan Yuan Yang - Peking University

Wenju Zhang - Shanghai University

Wenju Zhang - Shanghai University

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