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Ke Zhang
Life Science
Zhejiang University
Zhejiang
Language: Chinese, English
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Yeast Genomics Dna Polymerase Oxidative Stress Genome Instability Adaptive Evolution Environmental Stress Genetic Breeding Industrial Application Bioethanol Production
Areas of Focus
  • Genomic stability of brewing yeast
  • Adaptive evolution under environmental stress
Work Experience
  • 2021.7 to present, Zhejiang University, School of Life Sciences, Distinguished Research Fellow
  • 2017.7-2021.6, Zhejiang University, School of Life Sciences, Postdoctoral Researcher in Biology
  • 2012.9-2017.6, Zhejiang University, School of Life Sciences, PhD in Microbiology
Academic Background & Achievements
  • 2012-2017 PhD in Microbiology: Zhejiang University
  • 2015-2017 Visiting Scholar at Duke University, USA
  • 2008-2012 Bachelor in Biotechnology: Wuhan University of Technology
  • Published 18 papers as first or corresponding author in high-impact journals
Publications
  • Global genomic instability caused by reduced expression of DNA polymerase ε in yeast, Ke Zhang, 2022
  • Uncovering bleomycin-induced genomic alterations and underlying mechanisms in yeast, Ke Zhang, 2022
  • Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast, Ke Zhang, 2019
  • Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells, Ke Zhang, 2020
  • Effects of temperature on the meiotic recombination landscape of the yeast Saccharomyces cerevisiae, Ke Zhang, 2017
  • Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae, Ke Zhang, 2016
  • Global analysis of furfural-induced genomic instability using a yeast model, Ke Zhang, 2019
  • Genetic characterization and modification of a bioethanol-producing yeast strain, Ke Zhang, 2018
  • Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases, Ke Zhang, 2020
  • Mapping chromosomal instability induced by small-molecular therapeutics in a yeast model, Ke Zhang, 2019
  • Genome sequencing and genetic breeding of a bioethanol Saccharomyces cerevisiae strain YJS329, Ke Zhang, 2012
  • Genomic structural variation contributes to phenotypic change of industrial bioethanol yeast Saccharomyces cerevisiae, Ke Zhang, 2016
  • Effects of genome duplication on phenotypes and industrial applications of Saccharomyces cerevisiae strains, Ke Zhang, 2017
  • Comparative functional genomics to reveal the molecular basis of phenotypic diversities and guide the genetic breeding of industrial yeast strains, Ke Zhang, 2013
  • Genomic structural variations contribute to trait improvement during whole-genome shuffling (WGS) of yeast, Ke Zhang, 2014
  • Novel strategy to improve vanillin tolerance and ethanol fermentation performances of Saccharomycere cerevisiae strains, Ke Zhang, 2017
  • Construction of novel active dry yeast (ADY) Saccharomyces cerevisiae strains for bioethanol fermentation, Ke Zhang, 2013
  • Genomic reconstruction to improve bioethanol and ergosterol production of industrial yeast Saccharomyces cerevisiae, Ke Zhang, 2015
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