Professor | Wen Zhang | Asia Growth Partners

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Name	Wen Zhang
Contact Information	wenczhang@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Wen Zhang

Contact Information

wenczhang@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Veterinary Medicine
Academic Background & Achievements	2015-2019 PhD: National University of Singapore Selected as Shanghai Overseas High-level Talent 2023
Work Experience	2019-2023 - City of Hope National Medical Center, USA - Postdoctoral Researcher 2024-present - Shanghai Jiao Tong University, School of Agriculture and Biology - Associate Professor, Doctoral Supervisor
Awards	Shanghai Overseas High-level Talent 2023

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Veterinary Medicine

Academic Background & Achievements

2015-2019 PhD: National University of Singapore
Selected as Shanghai Overseas High-level Talent 2023

Work Experience

2019-2023 - City of Hope National Medical Center, USA - Postdoctoral Researcher
2024-present - Shanghai Jiao Tong University, School of Agriculture and Biology - Associate Professor, Doctoral Supervisor

Awards

Shanghai Overseas High-level Talent 2023

Areas of Focus	Pathogenic microorganisms and adaptive immune system interaction T cell differentiation regulation and immune response Pathogenesis and drug development of livestock inflammatory diseases
Publications	Regulatory function of steroid receptor coactivators (SRCs) in cell metabolism: implications for cancer and immunity, Zhang, W., Cao, X., Zhong, X., Wu, H., Shi, Y., & Sun, Z., 2023 SRC2 controls CD4+ T cell activation via stimulating c-Myc mediated up-regulation of amino acid transporter Slc7a5, Zhang, W., Cao, X., Zhong, X., Wu, H., Shi, Y., Feng, M., Wang, Y., Ann, D., Gwack Y., Shang, W., & Sun, Z., 2023 Steroid nuclear receptor coactivator 2 controls immune tolerance by promoting induced Treg differentiation via upregulating Nr4a2, Zhang, W., Cao, X., Zhong, X., Wu, H., Feng, M., Gwack Y., & Sun, Z., 2022 Pre-treatment of coconut kernels by proteases to modulate the flavour of coconut oil, Zhang, W., Chen, J., Lu, Y. & Liu, S., 2022 Aroma modulation of vegetable oils - a review, Zhang, W., Xu, C., & Liu, S., 2019 Solid-state fermentation of palm kernels by Yarrowia lipolytica modulates the aroma of palm kernel oil, Zhang, W., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2018 Viscozyme L pretreatment on palm kernels improved the aroma of palm kernel oil after kernel roasting, Zhang, W., Leong, S. M., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2018 Pretreatment of palm kernels with proteases modified volatile flavor compounds of palm kernel oil, Zhang, W., & Liu, S., 2018 Protease/peptidase (Flavourzyme) pretreatment on palm kernels improves the aroma of resultant palm kernel oil after kernel roasting, Zhang, W., Zhao F., Yang, T., & Liu, S., 2017 Celluclast 1.5 L pretreatment enhanced aroma of palm kernels and oil after kernel roasting, Zhang, W., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2017 Pentopan mono BG pretreatment of palm kernels modified the aroma of palm kernel oil after kernel roasting, Zhang, W., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2017 Changes in volatiles of palm kernel oil before and after kernel roasting, Zhang, W., Wang, R., Yuan, Y., Yang, T., & Liu, S., 2016 SRC-2 stimulates CD8+ T cell activation by up-regulating PGC-1α critical for mitochondrial function, Zhong, X., Wu, H., Ouyang, C., Zhang, W., Shi, Y., Wang, YC., Ann, D., Gwack, Y., Shang, W., & Sun, Z., 2023 Decoupling the role of RORγt in the differentiation and effector function of TH17 cells, Zhong, X., Wu, H., Zhang, W., Gwack, Y., Shang, W., Lee, K. O., Isakov, N., He, Z., & Sun, Z., 2022 Targeting macrophages for enhancing CD47 blockade-elicited lymphoma clearance and overcoming tumor-induced immunosuppression, Cao, X., Wang, Y., Zhang, W., Zhong, X., Gunes, GE., Dang, J., Wang, J., Epstein, AL., Querfeld, C., Sun, Z., Rosen, ST., & Feng, M., 2022 Promoting antibody-dependent cellular phagocytosis for effective macrophage-based cancer immunotherapy, Cao, X., Chen, J., Li, B., Dang, J., Zhang, W., Zhong, X., Wang, C., Raoof, M., Sun, Z., Yu, J., Fakih, MG. & Feng, M., 2022 Therapeutic potential of sulfur-containing natural products in inflammatory diseases, Cao, X, Cao, L, Zhang, W., Lu, R, Bian, JS, & Nie, X., 2020 Protective smell of hydrogen sulfide and polysulfide in cisplatin induced nephrotoxicity, Cao, X., Zhang, W., Moore, PK., & Bian, J., 2019

Areas of Focus

Pathogenic microorganisms and adaptive immune system interaction
T cell differentiation regulation and immune response
Pathogenesis and drug development of livestock inflammatory diseases

Publications

Regulatory function of steroid receptor coactivators (SRCs) in cell metabolism: implications for cancer and immunity, Zhang, W., Cao, X., Zhong, X., Wu, H., Shi, Y., & Sun, Z., 2023
SRC2 controls CD4+ T cell activation via stimulating c-Myc mediated up-regulation of amino acid transporter Slc7a5, Zhang, W., Cao, X., Zhong, X., Wu, H., Shi, Y., Feng, M., Wang, Y., Ann, D., Gwack Y., Shang, W., & Sun, Z., 2023
Steroid nuclear receptor coactivator 2 controls immune tolerance by promoting induced Treg differentiation via upregulating Nr4a2, Zhang, W., Cao, X., Zhong, X., Wu, H., Feng, M., Gwack Y., & Sun, Z., 2022
Pre-treatment of coconut kernels by proteases to modulate the flavour of coconut oil, Zhang, W., Chen, J., Lu, Y. & Liu, S., 2022
Aroma modulation of vegetable oils - a review, Zhang, W., Xu, C., & Liu, S., 2019
Solid-state fermentation of palm kernels by Yarrowia lipolytica modulates the aroma of palm kernel oil, Zhang, W., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2018
Viscozyme L pretreatment on palm kernels improved the aroma of palm kernel oil after kernel roasting, Zhang, W., Leong, S. M., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2018
Pretreatment of palm kernels with proteases modified volatile flavor compounds of palm kernel oil, Zhang, W., & Liu, S., 2018
Protease/peptidase (Flavourzyme) pretreatment on palm kernels improves the aroma of resultant palm kernel oil after kernel roasting, Zhang, W., Zhao F., Yang, T., & Liu, S., 2017
Celluclast 1.5 L pretreatment enhanced aroma of palm kernels and oil after kernel roasting, Zhang, W., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2017
Pentopan mono BG pretreatment of palm kernels modified the aroma of palm kernel oil after kernel roasting, Zhang, W., Zhao, F., Zhao, F., Yang, T., & Liu, S., 2017
Changes in volatiles of palm kernel oil before and after kernel roasting, Zhang, W., Wang, R., Yuan, Y., Yang, T., & Liu, S., 2016
SRC-2 stimulates CD8+ T cell activation by up-regulating PGC-1α critical for mitochondrial function, Zhong, X., Wu, H., Ouyang, C., Zhang, W., Shi, Y., Wang, YC., Ann, D., Gwack, Y., Shang, W., & Sun, Z., 2023
Decoupling the role of RORγt in the differentiation and effector function of TH17 cells, Zhong, X., Wu, H., Zhang, W., Gwack, Y., Shang, W., Lee, K. O., Isakov, N., He, Z., & Sun, Z., 2022
Targeting macrophages for enhancing CD47 blockade-elicited lymphoma clearance and overcoming tumor-induced immunosuppression, Cao, X., Wang, Y., Zhang, W., Zhong, X., Gunes, GE., Dang, J., Wang, J., Epstein, AL., Querfeld, C., Sun, Z., Rosen, ST., & Feng, M., 2022
Promoting antibody-dependent cellular phagocytosis for effective macrophage-based cancer immunotherapy, Cao, X., Chen, J., Li, B., Dang, J., Zhang, W., Zhong, X., Wang, C., Raoof, M., Sun, Z., Yu, J., Fakih, MG. & Feng, M., 2022
Therapeutic potential of sulfur-containing natural products in inflammatory diseases, Cao, X, Cao, L, Zhang, W., Lu, R, Bian, JS, & Nie, X., 2020
Protective smell of hydrogen sulfide and polysulfide in cisplatin induced nephrotoxicity, Cao, X., Zhang, W., Moore, PK., & Bian, J., 2019

Microorganisms Immune System Interaction T Cells Differentiation Regulation Immune Response Livestock Inflammatory Diseases Drug Development

Xueming Zhang - Jilin University

Li Kun - Nanjing Agricultural University

Zhihui Hao - China Agricultural University

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