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Fu Yi
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Vascular
Inflammation
Atherosclerosis
Pathophysiology
Human Physiology
Vascular Injury
Endothelial Function
Immune Response
Cell Signaling
Disease Progression
Areas of Focus
- Vascular inflammation and atherosclerosis
Work Experience
- 2009-2012 Postdoctoral Researcher in Vascular Pharmacology: Baker IDI Heart and Diabetes Institute, Australia
- 2012-present Researcher in Human Physiology: Department of Physiology and Pathophysiology, Peking University Health Science Center
Academic Background & Achievements
- 1999-2004 Bachelor of Clinical Medicine: West China School of Medicine, Sichuan University
- 2004-2009 PhD in Physiology: Peking University Health Science Center
- Published over 30 papers in journals like Cell Res, Circ Res, Blood, ATVB
- Received funding from the National Natural Science Foundation of China (2019)
Publications
- Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury, Fu Y et al., 2021
- The N6-methyladenosine (m6A)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of STAT1 mRNA, Fu Y et al., 2019
- Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage, Fu Y et al., 2018
- Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development, Fu Y et al., 2018
- Shift of Macrophage Phenotype due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification, Fu Y et al., 2016
- Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification, Fu Y et al., 2016
- The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy, Fu Y et al., 2016
- Cartilage oligomeric matrix protein is a natural inhibitor of thrombin, Fu Y et al., 2015
- Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages, Fu Y et al., 2012
- A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase β chain, Fu Y et al., 2011
