Professor | Fu Yi | Asia Growth Partners

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Name	Fu Yi
Language ability	Chinese, English
Province	Beijing

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Name

Fu Yi

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1999-2004 Bachelor of Clinical Medicine: West China School of Medicine, Sichuan University 2004-2009 PhD in Physiology: Peking University Health Science Center Published over 30 papers in journals like Cell Res, Circ Res, Blood, ATVB Received funding from the National Natural Science Foundation of China (2019)
Work Experience	2009-2012 Postdoctoral Researcher in Vascular Pharmacology: Baker IDI Heart and Diabetes Institute, Australia 2012-present Researcher in Human Physiology: Department of Physiology and Pathophysiology, Peking University Health Science Center

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1999-2004 Bachelor of Clinical Medicine: West China School of Medicine, Sichuan University
2004-2009 PhD in Physiology: Peking University Health Science Center
Published over 30 papers in journals like Cell Res, Circ Res, Blood, ATVB
Received funding from the National Natural Science Foundation of China (2019)

Work Experience

2009-2012 Postdoctoral Researcher in Vascular Pharmacology: Baker IDI Heart and Diabetes Institute, Australia
2012-present Researcher in Human Physiology: Department of Physiology and Pathophysiology, Peking University Health Science Center

Areas of Focus	Vascular inflammation and atherosclerosis
Publications	Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury, Fu Y et al., 2021 The N6-methyladenosine (m6A)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of STAT1 mRNA, Fu Y et al., 2019 Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage, Fu Y et al., 2018 Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development, Fu Y et al., 2018 Shift of Macrophage Phenotype due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification, Fu Y et al., 2016 Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification, Fu Y et al., 2016 The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy, Fu Y et al., 2016 Cartilage oligomeric matrix protein is a natural inhibitor of thrombin, Fu Y et al., 2015 Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages, Fu Y et al., 2012 A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase β chain, Fu Y et al., 2011

Areas of Focus

Vascular inflammation and atherosclerosis

Publications

Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury, Fu Y et al., 2021
The N6-methyladenosine (m6A)-forming enzyme METTL3 facilitates M1 macrophage polarization through the methylation of STAT1 mRNA, Fu Y et al., 2019
Cartilage oligomeric matrix protein is a novel notch ligand driving embryonic stem cell differentiation towards the smooth muscle lineage, Fu Y et al., 2018
Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development, Fu Y et al., 2018
Shift of Macrophage Phenotype due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification, Fu Y et al., 2016
Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification, Fu Y et al., 2016
The E3 ubiquitin ligase c-Cbl mediates integrin β1 ubiquitination during dilated cardiomyopathy, Fu Y et al., 2016
Cartilage oligomeric matrix protein is a natural inhibitor of thrombin, Fu Y et al., 2015
Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages, Fu Y et al., 2012
A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase β chain, Fu Y et al., 2011

Vascular Inflammation Atherosclerosis Pathophysiology Human Physiology Vascular Injury Endothelial Function Immune Response Cell Signaling Disease Progression

Xian Wang - Peking University

Yan Tang - Fudan University

Yuanyuan Wei - Fudan University

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