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Ya Bin Wei
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
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Depression Bipolar Treatment Mechanisms Childhood Autism Neurodevelopmental Pharmacogenomics Stem Cells Organoids
Areas of Focus
  • Depression and bipolar disorder mechanisms and treatment
  • Childhood autism and other neurodevelopmental disorders
  • Pharmacogenomics of neuropsychiatric diseases
  • Application of induced pluripotent stem cells and 3D brain organoids in neuropsychiatric diseases
Work Experience
  • 2016 - 2017 Scripps Research Institute - Postdoctoral Researcher
  • 2017 - 2019 University of California San Diego - Postdoctoral Researcher
  • 2020 - Present Peking University - Associate Researcher
Academic Background & Achievements
  • 2005 - 2010 Bachelor of Medicine: Peking University
  • 2011 - 2015 PhD: Karolinska Institutet
Publications
  • Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine, Maria Scherma et al., 2020
  • Peripheral cytokine levels and response to antidepressant treatment in depression: a systematic review and meta-analysis, Liu JJ, Wei YB et al., 2019
  • A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression, Wei YB et al., 2019
  • Stress, depressive status and telomere length: Does social interaction and coping strategy play a mediating role?, Liu JJ, Wei YB et al., 2017
  • Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression, Wei YB et al., 2016
  • MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro, Wei YB et al., 2016
  • hTERT genetic variation in depression, Wei YB et al., 2015
  • Telomerase dysregulation in the hippocampus of a rat model of depression. Normalization by lithium, Wei YB et al., 2015
  • Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene, Wei YB et al., 2014
  • Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres, Martinsson L, Wei YB et al., 2013
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