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Wen Gong Wang
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Transcription Factors
Rna-Binding Proteins
Gene Regulation
Mechanisms
Non-Coding Rna
Rna Roles
Genetic Control
Molecular Biology
Cellular Processes
Gene Expression
Areas of Focus
- Transcription factors and RNA-binding proteins mediated gene regulation mechanisms
- Role of non-coding RNA
Publications
- HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay, Wang W, 2010
- Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence, Wang W, 2010
- Reduced Nuclear Export of HuR mRNA by HuR Is Linked to the Loss of HuR in Replicative Senescence, Wang W, 2010
- Hydrogen peroxide induces p16INK4 through an AUF1-dependent manner, Wang W, 2010
- Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma, Wang W, 2010
- CSIG Regulates PTEN Translation in Replicative Senescence, Wang W, 2008
- Sp1 is Essential for p16INK4a Expression in Human Diploid Fibroblasts during Senescence, Wang W, 2007
- AUF1-Mediated mRNA Turnover is Responsible for Up-regulation of p16 during Replicative Senescence, Wang W, 2005
- AMPK-Regulated Acetylation and Phosphorylation of Importin-a1: Involvement in the Nuclear Import of RNA-binding Protein HuR, Wang W, 2004
- Prostaglandin A2-mediated Stabilization of p21 mRNA through an ERK-dependent Pathway Requiring RNA-binding Protein HuR, Wang W, 2004
- Influence of RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells, Wang W, 2003
- Increased AMP: ATP Ratio and AMP-activated Protein Kinase Activity during Cellular Senescence Linked to Reduced HuR Function, Wang W, 2003
- Global Analysis of Stress-Regulated mRNA Turnover by Using cDNA Arrays, Wang W, 2002
- AMP-Activated Kinase Regulates Cytoplasm HuR, Wang W, 2002
- Loss of HuR is Linked to Reduced Expression of Proliferative Genes during Replicative Senescence, Wang W, 2001
- Down-regulation of Cyclin D1 Expression by Prostagladin A2 Is Mediated by Enhanced mRNA Turnover Associated with Binding of AUF1, Wang W, 2000
- HuR Regulates Cyclin A and Cyclin B1 mRNA Stability during Cell Proliferation, Wang W, 2000
- HuR Regulates p21 mRNA Stabilization by Ultraviolet light, Wang W, 2000
- Extracellular Matrix Inhibits Apoptosis and Enhances Endothelial Differentiation by a NF-kB-dependent Mechanism, Wang W, 1999
