Professor | Wen Gong Wang | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Wen Gong Wang
Contact Information	wwg@bjmu.edu.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Wen Gong Wang

Contact Information

wwg@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Areas of Focus	Transcription factors and RNA-binding proteins mediated gene regulation mechanisms Role of non-coding RNA
Publications	HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay, Wang W, 2010 Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence, Wang W, 2010 Reduced Nuclear Export of HuR mRNA by HuR Is Linked to the Loss of HuR in Replicative Senescence, Wang W, 2010 Hydrogen peroxide induces p16INK4 through an AUF1-dependent manner, Wang W, 2010 Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma, Wang W, 2010 CSIG Regulates PTEN Translation in Replicative Senescence, Wang W, 2008 Sp1 is Essential for p16INK4a Expression in Human Diploid Fibroblasts during Senescence, Wang W, 2007 AUF1-Mediated mRNA Turnover is Responsible for Up-regulation of p16 during Replicative Senescence, Wang W, 2005 AMPK-Regulated Acetylation and Phosphorylation of Importin-a1: Involvement in the Nuclear Import of RNA-binding Protein HuR, Wang W, 2004 Prostaglandin A2-mediated Stabilization of p21 mRNA through an ERK-dependent Pathway Requiring RNA-binding Protein HuR, Wang W, 2004 Influence of RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells, Wang W, 2003 Increased AMP: ATP Ratio and AMP-activated Protein Kinase Activity during Cellular Senescence Linked to Reduced HuR Function, Wang W, 2003 Global Analysis of Stress-Regulated mRNA Turnover by Using cDNA Arrays, Wang W, 2002 AMP-Activated Kinase Regulates Cytoplasm HuR, Wang W, 2002 Loss of HuR is Linked to Reduced Expression of Proliferative Genes during Replicative Senescence, Wang W, 2001 Down-regulation of Cyclin D1 Expression by Prostagladin A2 Is Mediated by Enhanced mRNA Turnover Associated with Binding of AUF1, Wang W, 2000 HuR Regulates Cyclin A and Cyclin B1 mRNA Stability during Cell Proliferation, Wang W, 2000 HuR Regulates p21 mRNA Stabilization by Ultraviolet light, Wang W, 2000 Extracellular Matrix Inhibits Apoptosis and Enhances Endothelial Differentiation by a NF-kB-dependent Mechanism, Wang W, 1999

Areas of Focus

Transcription factors and RNA-binding proteins mediated gene regulation mechanisms
Role of non-coding RNA

Publications

HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay, Wang W, 2010
Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence, Wang W, 2010
Reduced Nuclear Export of HuR mRNA by HuR Is Linked to the Loss of HuR in Replicative Senescence, Wang W, 2010
Hydrogen peroxide induces p16INK4 through an AUF1-dependent manner, Wang W, 2010
Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma, Wang W, 2010
CSIG Regulates PTEN Translation in Replicative Senescence, Wang W, 2008
Sp1 is Essential for p16INK4a Expression in Human Diploid Fibroblasts during Senescence, Wang W, 2007
AUF1-Mediated mRNA Turnover is Responsible for Up-regulation of p16 during Replicative Senescence, Wang W, 2005
AMPK-Regulated Acetylation and Phosphorylation of Importin-a1: Involvement in the Nuclear Import of RNA-binding Protein HuR, Wang W, 2004
Prostaglandin A2-mediated Stabilization of p21 mRNA through an ERK-dependent Pathway Requiring RNA-binding Protein HuR, Wang W, 2004
Influence of RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells, Wang W, 2003
Increased AMP: ATP Ratio and AMP-activated Protein Kinase Activity during Cellular Senescence Linked to Reduced HuR Function, Wang W, 2003
Global Analysis of Stress-Regulated mRNA Turnover by Using cDNA Arrays, Wang W, 2002
AMP-Activated Kinase Regulates Cytoplasm HuR, Wang W, 2002
Loss of HuR is Linked to Reduced Expression of Proliferative Genes during Replicative Senescence, Wang W, 2001
Down-regulation of Cyclin D1 Expression by Prostagladin A2 Is Mediated by Enhanced mRNA Turnover Associated with Binding of AUF1, Wang W, 2000
HuR Regulates Cyclin A and Cyclin B1 mRNA Stability during Cell Proliferation, Wang W, 2000
HuR Regulates p21 mRNA Stabilization by Ultraviolet light, Wang W, 2000
Extracellular Matrix Inhibits Apoptosis and Enhances Endothelial Differentiation by a NF-kB-dependent Mechanism, Wang W, 1999

Transcription Factors Rna-Binding Proteins Gene Regulation Mechanisms Non-Coding Rna Rna Roles Genetic Control Molecular Biology Cellular Processes Gene Expression

Lin Wang - Wuhan University

Zhongjie Li - Zhejiang University

Zhong Zhen - Zhejiang University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us