2019: Green Leaf Biopharmaceutical Outstanding Young Scholar Award, Peking University
2016: Nomination Award, China Heart Congress (CHC) Young Scientist
2016: Bayer Investigator Award
2013: Supported by the 37th International Congress of Physiological Sciences, Chinese Physiological Society
2012: Green Leaf Biopharmaceutical Outstanding Young Scholar Award, Peking University
2011: Second Prize, Zhang Xijun Foundation of the Chinese Physiological Society, 11th National Young Excellent Physiology Paper
2010: Outstanding Postdoctoral Title, Peking University
2010: Richard J Bing Young Scientist Award, Finalist, 20th World Congress of the International Society for Heart Research (ISHR)
Research
Cardiovascular physiology and pathophysiology Myocardial cell injury and protection mechanisms
Structure-based design of non-hypertrophic apelin receptor modulator, Wang WW, Ji SY, Zhang W, Zhang J, Cai C, Hu R, Zang SK, Miao L, Xu H, Chen LN, Yang Z, Guo J, Qin J, Shen DD, Liang P, Zhang Y, Zhang Y, 2024
Single-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration, Wu Z, Shi Y, Cui Y, Xing X, Zhang L, Liu D, Zhang Y, Dong J, Jin L, Pang M, Xiao RP, Zhu Z, Xiong JW, Tong X, Zhang Y, Wang S, Tang F, Zhang B, 2023
Refining prediction of stroke in sinus node dysfunction patients without atrial fibrillation using a P-combined score: a multi-centre study, Dong H, Zhang Y, Sun D, Wang G, Zhang Q, Hidru TH, Yang Y, Wang S, Wei Y, Liu F, Zhang J, Xia Y, Yang X, 2023
Novel CaMKII-δ inhibitor hesperadin exerts dual functions to ameliorate cardiac ischemia/reperfusion injury and inhibit tumor growth, Zhang J, Liang R, Wang K, Zhang W, Zhang M, Jin L, Xie P, Zheng W, Shang H, Hu Q, Li J, Chen G, Wu F, Lan F, Wang L, Wang S.Q., Li Y, Zhang Y, Liu J, Lv F, Hu X, Xiao R.P., Lei X, Zhang Y, 2022
Targeting CaMKII-δ9 Ameliorates Cardiac Ischemia/reperfusion Injury by Inhibiting Myocardial Inflammation, Yao Y, Li F, Zhang M, Jin L, Xie P, Liu D, Zhang J, Hu X, Lv F, Shang H, Zheng W, Sun X, Duanmu J, Wu F, Lan F, Xiao RP., Zhang Y, 2022
MG53 E3 ligase-dead mutant protects diabetic hearts from acute ischemic/reperfusion injury and ameliorates diet-induced cardiometabolic damage, Feng H, Shen H, Robeson MJ, Wu YH, Wu HK., Chen GJ, Zhang S, Xie P, Jin L, He Y, Wang Y, Lv F, Hu X, Zhang Y, Xiao RP, 2022
CaMKII-δ9 induces cardiomyocyte death to promote cardiomyopathy and heart failure, Zhang M, Zhang J, Zhang W, Hu Q, Jin L, Xie P, Zheng W, Shang H, Zhang Y, 2022
Heterodimerization with 5-HT2BR is indispensable for b2AR-mediated cardioprotection, Song Y, Xu C, Liu J, Li Y, Wang H, Shan D, Wainer I, Hu X, Zhang Y, Woo YH, Xiao RP, 2021
β-Arrestin2 Inhibits the Apoptosis and Facilitates the Proliferation of Fibroblast-like Synoviocytes in Diffuse-type Tenosynovial Giant Cell Tumor, Cao C, Zhang Y, Cheng J, Wu F, Niu X, Hu X, Duan X, Fu X, Zhang J, Zhang X, Ao Y, 2021
Cardiac ischemic preconditioning promotes MG53 secretion through H2O2-activated PKC-d signaling, Shan D, Guo S, Wu HK, Lv F, Jin L, Zhang M, Xie P, Wang Y, Song Y, Wu F, Lan F, Hu X, Cao CM, Zhang Y, Xiao RP, 2020
CaMKII-d9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair, Zhang M, Gao H, Liu D, Zhong X, Shi X, Yu P, Jin L, Liu Y, Tang Y, Song Y, Liu J, Hu X, Li CY, Song L, Qin J, Wu F, Lan F, Zhang Y, Xiao RP, 2019
Glucose-sensitive myokine/cardiokine MG53 regulates systemic insulin response and metabolic homeostasis, Wu HK, Zhang Y, Cao CM, Hu X, Fang M, Yao Y, Jin L, Chen G, Jiang P, Zhang S, Song R, Peng W, Liu F, Guo J, Tang L, He Y, Shan D, Huang J, Zhou Z, Wang D, Lv F, Xiao RP, 2019
β-arrestin 2 mediates cardiac ischemia-reperfusion injury via inhibiting GPCR-independent cell survival signaling, Wang Y, Jin L, Song Y, Zhang M, Shan D, Liu Y, Lv F, Xiao RP, Zhang Y, 2017
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis, Zhang T, Zhang Y, Cui M, Jin L, Wang Y, Lv F, Liu Y, Zheng W, Shang H, Zhang J, Zhang M, Wu HK, Guo J, Zhang X, Hu X, Cao CM, Xiao RP, 2016
Eplerenone restores 24-h blood pressure circadian rhythm and reduces advanced glycation end-products in rhesus macaques with spontaneous hypertensive metabolic syndrome, Zhang Y, Zheng W, Liu Y, Wang J, Peng Y, Shang H, Hou N, Hu X, Ding Y, Xiao Y, Wang C, Zeng F, Mao J, Zhang J, Ma D, Sun X, Li C, Xiao RP, Zhang X, 2016
Interaction of β1-adrenoceptor with RAGE mediates cardiomyopathy via CaMKII signaling, Zhu W, Tsang S, Browe, DM, Woo AY, Huang Y, Xu C, Liu JF, Lv F, Zhang Y, Xiao RP, 2016
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders, Song RS, Peng W, Zhang Y, Lv F, Wu HK, Guo J, Cao Y, Pi Y, Zhang X, Jin L, Zhang M, Jiang P, Liu F, Meng S, Zhang X, Jiang P, Cao CM, Xiao RP, 2013
MG53 participates in ischemic postconditioning through the RISK signaling pathway, Cao CM, Zhang Y, Weisleder N, Ferrante C, Wang X, Lv F, Zhang Y, Song R, Hwang M, Jin L, Guo J, Peng W, Li G, Nishi M, Takeshima H, Ma J, Xiao RP, 2011