Professor | Yingyu Chen | Asia Growth Partners

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Name	Yingyu Chen
Contact Information	yingyu_chen@bjmu.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Yingyu Chen

Contact Information

yingyu_chen@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1980.9-1985.7 Bachelor of Medicine, Binzhou Medical University, Shandong 1990.9-1993.7 Master of Medicine in Immunology, Beijing Medical University 1998.9-2001.7 PhD in Immunology, Peking University Postdoctoral Researcher, Institute of Zoology, Chinese Academy of Sciences
Work Experience	2001.7-2003.6 Postdoctoral Researcher, Institute of Zoology, CAS 2003.7-present Associate Professor, Professor, Peking University
Awards	2003 December: Second Prize for Excellent PhD Thesis, Peking University 2002 February: First Prize, Science and Technology Award by Chinese Universities 2005 January: Second Prize, Natural Science Award by Ministry of Education

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1980.9-1985.7 Bachelor of Medicine, Binzhou Medical University, Shandong
1990.9-1993.7 Master of Medicine in Immunology, Beijing Medical University
1998.9-2001.7 PhD in Immunology, Peking University
Postdoctoral Researcher, Institute of Zoology, Chinese Academy of Sciences

Work Experience

2001.7-2003.6 Postdoctoral Researcher, Institute of Zoology, CAS
2003.7-present Associate Professor, Professor, Peking University

Awards

2003 December: Second Prize for Excellent PhD Thesis, Peking University
2002 February: First Prize, Science and Technology Award by Chinese Universities
2005 January: Second Prize, Natural Science Award by Ministry of Education

Areas of Focus	Human functional genomics Molecular mechanisms of apoptosis and autophagy Signal transduction pathways Roles in tumors and autoimmune diseases Monoclonal antibody preparation and ELISA kit development
Publications	PDCD5 negatively regulates autoimmunity by upregulating FOXP3+ regulatory T cells and suppressing Th17 and Th1 responses, Yingyu Chen et al., 2013 Adenovirus vector-mediated FAM176A overexpression induces cell death in human H1299 non–small cell lung cancer cells, Yingyu Chen et al., 2013 A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy, Yingyu Chen et al., 2013 Adenovirus vector-mediated expression of TMEM166 inhibits human cancer cell growth by autophagy and apoptosis in vitro and in vivo, Yingyu Chen et al., 2013 Transmembrane Protein 208: A Novel ER-Localized Protein That Regulates Autophagy and ER Stress, Yingyu Chen et al., 2013 Serum programmed cell death protein 5 (PDCD5) levels is upregulated in liver diseases, Yingyu Chen et al., 2013 Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats, Yingyu Chen et al., 2012 Expression of TMEM166 protein in human normal and tumor tissues, Yingyu Chen et al., 2012 Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cell balance, Yingyu Chen et al., 2012 PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway, Yingyu Chen et al., 2012 Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo, Yingyu Chen et al., 2010 Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma, Yingyu Chen et al., 2010 PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis, Yingyu Chen et al., 2009 Structure-function correlation of human programmed cell death 5 protein, Yingyu Chen et al., 2009

Areas of Focus

Human functional genomics
Molecular mechanisms of apoptosis and autophagy
Signal transduction pathways
Roles in tumors and autoimmune diseases
Monoclonal antibody preparation and ELISA kit development

Publications

PDCD5 negatively regulates autoimmunity by upregulating FOXP3+ regulatory T cells and suppressing Th17 and Th1 responses, Yingyu Chen et al., 2013
Adenovirus vector-mediated FAM176A overexpression induces cell death in human H1299 non–small cell lung cancer cells, Yingyu Chen et al., 2013
A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy, Yingyu Chen et al., 2013
Adenovirus vector-mediated expression of TMEM166 inhibits human cancer cell growth by autophagy and apoptosis in vitro and in vivo, Yingyu Chen et al., 2013
Transmembrane Protein 208: A Novel ER-Localized Protein That Regulates Autophagy and ER Stress, Yingyu Chen et al., 2013
Serum programmed cell death protein 5 (PDCD5) levels is upregulated in liver diseases, Yingyu Chen et al., 2013
Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats, Yingyu Chen et al., 2012
Expression of TMEM166 protein in human normal and tumor tissues, Yingyu Chen et al., 2012
Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cell balance, Yingyu Chen et al., 2012
PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway, Yingyu Chen et al., 2012
Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo, Yingyu Chen et al., 2010
Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma, Yingyu Chen et al., 2010
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis, Yingyu Chen et al., 2009
Structure-function correlation of human programmed cell death 5 protein, Yingyu Chen et al., 2009

Genomics Apoptosis Autophagy Signal Transduction Tumors Autoimmune Diseases Monoclonal Antibodies Elisa Molecular Biology Biomedical Research

Tanjun Tong - Peking University

Jinbiao Zhan - Zhejiang University

Chunlan Yan - Zhejiang University

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