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Yingyu Chen
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Genomics
Apoptosis
Autophagy
Signal Transduction
Tumors
Autoimmune Diseases
Monoclonal Antibodies
Elisa
Molecular Biology
Biomedical Research
Areas of Focus
- Human functional genomics
- Molecular mechanisms of apoptosis and autophagy
- Signal transduction pathways
- Roles in tumors and autoimmune diseases
- Monoclonal antibody preparation and ELISA kit development
Work Experience
- 2001.7-2003.6 Postdoctoral Researcher, Institute of Zoology, CAS
- 2003.7-present Associate Professor, Professor, Peking University
Academic Background & Achievements
- 1980.9-1985.7 Bachelor of Medicine, Binzhou Medical University, Shandong
- 1990.9-1993.7 Master of Medicine in Immunology, Beijing Medical University
- 1998.9-2001.7 PhD in Immunology, Peking University
- Postdoctoral Researcher, Institute of Zoology, Chinese Academy of Sciences
Publications
- PDCD5 negatively regulates autoimmunity by upregulating FOXP3+ regulatory T cells and suppressing Th17 and Th1 responses, Yingyu Chen et al., 2013
- Adenovirus vector-mediated FAM176A overexpression induces cell death in human H1299 non–small cell lung cancer cells, Yingyu Chen et al., 2013
- A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy, Yingyu Chen et al., 2013
- Adenovirus vector-mediated expression of TMEM166 inhibits human cancer cell growth by autophagy and apoptosis in vitro and in vivo, Yingyu Chen et al., 2013
- Transmembrane Protein 208: A Novel ER-Localized Protein That Regulates Autophagy and ER Stress, Yingyu Chen et al., 2013
- Serum programmed cell death protein 5 (PDCD5) levels is upregulated in liver diseases, Yingyu Chen et al., 2013
- Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats, Yingyu Chen et al., 2012
- Expression of TMEM166 protein in human normal and tumor tissues, Yingyu Chen et al., 2012
- Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cell balance, Yingyu Chen et al., 2012
- PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway, Yingyu Chen et al., 2012
- Recombinant human PDCD5 sensitizes chondrosarcomas to cisplatin chemotherapy in vitro and in vivo, Yingyu Chen et al., 2010
- Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma, Yingyu Chen et al., 2010
- PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis, Yingyu Chen et al., 2009
- Structure-function correlation of human programmed cell death 5 protein, Yingyu Chen et al., 2009
Awards
- 2003 December: Second Prize for Excellent PhD Thesis, Peking University
- 2002 February: First Prize, Science and Technology Award by Chinese Universities
- 2005 January: Second Prize, Natural Science Award by Ministry of Education
