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Zhong Chao
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Systems Biology
Transcription
Metabolic Regulation
Immune System
Mucosal Immunity
Homeostasis
Disease Process
Tumor Immunity
Cancer Development
Cancer Treatment
Areas of Focus
- Systems biology approaches to transcription and metabolic regulation in the immune system
- Key regulatory molecules in mucosal immune system homeostasis and disease
- New mechanisms of tumor immunity affecting cancer development and treatment
Work Experience
- 2016 - Present: Researcher at Peking University Health Science Center
- 2012 - 2016: Postdoctoral Fellow at the National Institutes of Health, USA
- 2006 - 2012: PhD Candidate at the Institute of Biophysics, Chinese Academy of Sciences
Academic Background & Achievements
- 2016 - PhD: Institute of Biophysics, Chinese Academy of Sciences
- 2002 - Bachelor: University of Science and Technology of China
Publications
- IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy, Zhong C et al., 2023
- Proline uptake promotes activation of lymphoid tissue inducer cells to maintain gut homeostasis, Zhong C et al., 2023
- Genetic distinction between functional tissue-resident and conventional natural killer cells, Zhong C et al., 2023
- PD-1 signaling facilitates LTi activation through restraining fatty acid oxidation, Zhong C et al., 2022
- Proximal and distal regions of pathogenic Th17 related chromatin loci are sequentially accessible during pathogenicity of Th17, Zhong C et al., 2022
- Deciphering cell type-specific gene expression signatures of cardiac diseases through reconstruction of bulk transcriptomes, Zhong C et al., 2022
- Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells, Zhong C et al., 2020
- Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment, Zhong C et al., 2016
- The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells, Zhong C et al., 2014
- Granzyme K inhibits replication of influenza virus through cleaving the nuclear transport complex importin α1/β dimer of infected host cells, Zhong C et al., 2012
