Areas of Focus
- HBV infection, especially chronic infection, leading to chronic hepatitis B, cirrhosis, and liver cancer
Academic Background & Achievements
- Bachelor's Degree: Beijing Agricultural University
- Master's Degree: Tsinghua University
- PhD: Umeå University, Sweden
- Never left the field of microbiology since entering university, worked in agricultural, environmental, industrial, and medical microbiology.
Publications
- Naturally occurring mutations within HBV surface promoter II sequences affect transcription activity, HBsAg and HBV DNA levels in HBeAg-positive chronic hepatitis B patients., Hao R, Xiang K, Shi Y, Zhao D, Tian H, Xu B, Zhu Y, Dong H, Ding H, Zhuang H, Hu J, Li T, 2019
- The effect of the hepatitis B virus surface protein truncated sC69 mutation on viral infectivity and the host innate immune response., Xiang K, Xiao Y, Li Y, He L, Wang L, Zhuang H, Li T, 2019
- The modulation of HBsAg level by sI126T is affected by additional amino acid substitutions in the S region of HBV., He L, Su M, Ou G, Wang L, Deng J, Zhuang H, Xiang K, Li T, 2019
- Impacts of HBV rtH55R polymerase substitution on viral replication and rtM204I/V resistance to nucleoside/nucleotide antiviral drugs., Xiang K, Zhao C, Wang S, Li Y, Su M, Wang Q, Xu X, Deng J, Zhuang H, Li T, 2018
- Novel HBV recombinants between genotypes B and C in 3'-terminal reverse transcriptase (RT) sequences are associated with enhanced viral DNA load, higher RT point mutation rates and place of birth among Chinese patients., Liu B, Yang J, Yan L, Zhuang H, Li T, 2018
Awards
- Qinhuangdao City Science and Technology Progress First Prize
- Hebei Province Science and Technology Progress Third Prize
- Peking University Basic Medical College SCI Paper Citation Award
- Peking University Basic Medical College Excellent SCI Paper Award