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Huan Wang
Basic Medical Sciences
Peking University
Beijing
Language: English, Chinese
Cardiotoxicity
Cancer Drugs
Tyrosine Kinase Inhibitors
Immune Checkpoint Inhibitors
Transcriptomics
Proteomics
Metabolomics
Cardiac Regeneration
Tissue Engineering
Biomedical Engineering
Areas of Focus
- Drug-induced cardiotoxicity
- Integrative multi-omics data analysis
- Cardiac muscle tissue engineering
Work Experience
- 2018.7 - present: Peking University Health Science Center, Institute of Systems Biomedicine, Associate Research Fellow
- 2014.9 - 2018.6: Harvard Medical School, Department of Systems Biology, Postdoctoral Fellow (Adviser: Peter K. Sorger)
- 2013.5 - 2014.9: University of Colorado at Boulder, Chemical and Biological Engineering, Postdoctoral Fellow (Adviser: Kristi S. Anseth)
Academic Background & Achievements
- 2002-2006 B.S. in Biotechnology: Zhejiang University (graduated with summa cum laude)
- 2006-2013 PhD in Molecular, Cellular and Developmental Biology: University of Colorado at Boulder (Advisers: Leslie A. Leinwand and Kristi Anseth)
Publications
- Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming, Wang H et al., 2019
- Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway, Wang H et al., 2013
- Cardiac valve cells and their microenvironment—insights from in vitro studies, Wang H et al., 2014
- Roles of transforming growth factor-β1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation, Wang H et al., 2014
- Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus, Wang H et al., 2012
- Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves, Wang H et al., 2013
